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It emphasizes how technological refinements and their validations from the prior decade are incorporated into allergists/clinical immunologists’ diagnostic tools to confirm human clinical sensitivity. The document defines “allergy” as major categories of human hypersensitivity, outlines scope focused on adaptive immunity, and updates prior 1988 and 1995 practice parameters by integrating an expanded research database while aiming for balanced use of classic and newer diagnostic methods.",{"@graph":63,"@context":118},[64,80,101],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":51,"@type":70,"position":76},"https://docshare.wps.com/template/general/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/allergy-diagnostic-testing-an-updated-practice-parameter-practice-parameter-volume-100-number-3-supplement-3/563822/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/allergy-diagnostic-testing-an-updated-practice-parameter-practice-parameter-volume-100-number-3-supplement-3/563822.png","ImageObject",442,249,{"name":88,"@type":89},"Ben ","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/pdf","2026-10-25","2026-10-12",true,{"@type":98,"interactionType":99,"userInteractionCount":76},"InteractionCounter",{"@type":100},"ViewAction",{"@type":102,"mainEntity":103},"FAQPage",[104,110,114],{"name":105,"@type":106,"acceptedAnswer":107},"What is the main purpose of this updated practice parameter?","Question",{"text":108,"@type":109},"It focuses on incorporating technological refinements validated over the past decade into allergy diagnostic practice to confirm human clinical sensitivity and provide updated evidence-based recommendations.","Answer",{"name":111,"@type":106,"acceptedAnswer":112},"How does the document define “allergy” for its scope?",{"text":113,"@type":109},"It defines “allergy” as major categories of human hypersensitivity, emphasizing pertinent clinical immunologic techniques oriented to adaptive immunity rather than infection, cancer, or transplantation immunology.",{"name":115,"@type":106,"acceptedAnswer":116},"Why was the 1995 allergy diagnostic parameter updated?",{"text":117,"@type":109},"The document explains that major advances in basic and translational immunologic research since 1995 created the need for an overhaul, using an expanded database to achieve balanced use of classic and newer diagnostic methods.","https://schema.org",{"og:url":78,"og:type":120,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":122,"canonical":78},"index,follow",{"doc_id":124,"site_id":56},563822,1792694760,{"code":4,"msg":5,"data":127},{"doc_id":124,"user_id":128,"nickname":88,"user_avatar":129,"doc_module":9,"category_id":50,"category_name":51,"doc_title":59,"doc_description":61,"doc_content":130,"file_id":131,"file_url":132,"file_type":133,"file_size":134,"view_count":76,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":135,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":140,"read_time":141},2336478951081,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","ANNALS OF ALLERGY, ASTHMA, & IMMUNOLOGY  \nMarch 2008; Volume 100, Number 3, Supplement 3  \nAllergy Diagnostic Testing: An Updated Practice Parameter  \nPractice Parameter  \nAllergy Diagnostic Testing: An Updated Practice Parameter  \nI. Leonard Bernstein, MD; James T. Li, MD, PhD; David I. Bernstein, MD;  \nRobert Hamilton, PhD, DABMLI; Sheldon L. Spector, MD; Ricardo Tan, MD; Scott Sicherer, MD; David B. K. Golden, MD; David A. Khan, MD; Richard A. Nicklas, MD; Jay M. Portnoy, MD;  \nJoann Blessing-Moore, MD; Linda Cox, MD; David M. Lang, MD; John Oppenheimer, MD;  \nChristopher C. Randolph, MD; Diane E. Schuller, MD; Stephen A. Tilles, MD; Dana V. Wallace, MD; Estelle Levetin, PhD; and Richard Weber, MD  \nTABLE OF CONTENTS  \nI. Preface .................................................................................... S2  \nII. Executive Summary ......................................................................... S3  \nIII. Collation of Summary Statements .............................................................. S5  \nIV. Part 1 .................................................................................... S 15  \nV. In Vivo Diagnostic Tests of Immediate Hypersensitivity Reactions .................................. S 15  \nVI. Organ Challenge Tests ...................................................................... S29  \nVII. Tests to Distinguish Clinical Obstructive Diseases Resembling Asthma ............................... S33  \nVIII. In Vivo Diagnostic Tests of Cell-Mediated Immunity ............................................. S34  \nIX. In Vitro Diagnostic Tests of Immediate Hypersensitivity ........................................... S43  \nX. In Vitro Diagnostic Tests of Cell-Mediated Immunity ............................................. S59  \nXI. Other Diagnostic Immunologic Tests ........................................................... S64  \nXII. Unproven Tests ............................................................................ S65  \nXIII. Part 2 .................................................................................... S66  \nXIV. Allergens ................................................................................. S67  \nXV. Assessment of Inhalant Allergy ............................................................... S74  \nXVI. Assessment of Food Allergy................................................................. S 102  \nXVII. Assessment of Stinging Insect Allergy ........................................................ S 106  \nXVIII. Assessment of Drug Allergy................................................................. S 109  \nXIX. Assessment of Allergic Contact Dermatitis ..................................................... S 115  \nXX. Acknowledgments ......................................................................... S 121  \nXXI. References ............................................................................... S 122  \nThe American Academy of Allergy, Asthma and Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI) have jointly accepted responsibility for establishing the Allergy Diagnostic Testing: An Updated Practice Parameter. This is a complete and comprehensive document at the current time. The medical environment is a changing environment and not all recommendations will be appropriate for all patients. Because this document incorporated the efforts of many participants, no single individual, including those who served on the Joint Task Force, is authorized to provide an official  \nAAAAI or ACAAI interpretation of these practice parameters. Any request for information about or an interpretation of these practice parameters by the AAAAI or ACAAI should be directed to the Executive Offices of the AAAAI, the ACAAI, and the Joint Council of Allergy, Asthma and Immunology. These parameters are not designed for use by pharmaceutical companies in drug promotion.  \nReceived for publication October 27, 2007; Accepted for ","cbCainNV83PQgfn4","https://ap.wps.com/l/cbCainNV83PQgfn4","pdf",850191,149,"English","# Preface\n# Executive Summary\n# Collation of Summary Statements\n# Part 1\n## In Vivo Diagnostic Tests of Immediate Hypersensitivity Reactions\n## Organ Challenge Tests\n## Tests to Distinguish Clinical Obstructive Diseases Resembling Asthma\n## In Vivo Diagnostic Tests of Cell-Mediated Immunity\n## In Vitro Diagnostic Tests of Immediate Hypersensitivity\n## In Vitro Diagnostic Tests of Cell-Mediated Immunity\n## Other Diagnostic Immunologic Tests\n## Unproven Tests\n# Part 2\n## Allergens\n## Assessment of Inhalant Allergy\n## Assessment of Food Allergy\n## Assessment of Stinging Insect Allergy\n## Assessment of Drug Allergy\n## Assessment of Allergic Contact Dermatitis\n# Acknowledgments\n# References","[{\"question\":\"What is the main purpose of this updated practice parameter?\",\"answer\":\"It focuses on incorporating technological refinements validated over the past decade into allergy diagnostic practice to confirm human clinical sensitivity and provide updated evidence-based recommendations.\"},{\"question\":\"How does the document define “allergy” for its scope?\",\"answer\":\"It defines “allergy” as major categories of human hypersensitivity, emphasizing pertinent clinical immunologic techniques oriented to adaptive immunity rather than infection, cancer, or transplantation immunology.\"},{\"question\":\"Why was the 1995 allergy diagnostic parameter updated?\",\"answer\":\"The document explains that major advances in basic and translational immunologic research since 1995 created the need for an overhaul, using an expanded database to achieve balanced use of classic and newer diagnostic methods.\"}]","Allergy Diagnostic Testing: An Updated Practice Parameter - Practice Parameter - Volume 100 - Number 3 - Supplement 3 | PDF",1791838733,52]