[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-187176-en":3,"doc-seo-187176-105":30,"detail-sidebar-cat-1-en-105":91},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":11,"category_id":12,"category_name":13,"doc_title":14,"doc_description":15,"doc_content":16,"file_id":17,"file_url":18,"file_type":19,"file_size":20,"view_count":4,"is_deleted":4,"is_public":11,"is_downloadable":11,"audit_status":11,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":15,"update_tm":28,"read_time":29},187176,2336464648746,"Skyler","https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c",1,158,"General","2018-Nowak-Sliwinska-Angiogenesis","This document presents a comprehensive overview of research into angiogenesis, the formation of new blood vessels. It details various experimental models and assays used to study this process, including the Fibrin bead assay, Collagen lumen assay, Retina explant assay, and the Vascularized micro-organ model. Each assay is evaluated for its effectiveness in assessing key angiogenic processes such as sprouting, lumen formation, anastomosis, pericyte recruitment, perfusion, and pruning. The accompanying figures visually represent these assays and their outcomes, including microscopy images of endothelial cell sprouting and lumen formation in different matrices, flow cytometry data showing cell cycle distribution, and dose-response curves illustrating the effect of sunitinib on cell viability. The research emphasizes the multifaceted nature of angiogenesis and the importance of utilizing appropriate experimental techniques to dissect its complex mechanisms. The data suggests an in-depth exploration of therapeutic interventions targeting angiogenesis, likely for applications in disease treatment and tissue engineering, underpinned by robust experimental validation.","| Assay | Process |  |  |  |  |  |\n| --- | --- | --- | --- | --- | --- | --- |\n|  | Sprouting | Lumen formation | Anastomosis | Pericyte recruitment | Perfusion | Pruning |\n| Fibrin bead assay | ✓ | ✓ | ✓ | ✓ |  |  |\n| Collagen lumen assay |  | ✓ |  | ✓ |  |  |\n| Retina explant assay | ✓ | ✓ | ✓ |  |  |  |\n| Vascularized micro-organ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |","cbCaidKMMc5RHNDt","https://ap.wps.com/l/cbCaidKMMc5RHNDt","pdf",3267327,108,"English","en",105,"","[{\"question\":\"What are the different assays used to study angiogenesis in this document?\",\"answer\":\"The document describes the Fibrin bead assay, Collagen lumen assay, Retina explant assay, and the Vascularized micro-organ model for studying angiogenesis.\"},{\"question\":\"What key angiogenic processes are assessed by these assays?\",\"answer\":\"These assays are used to evaluate sprouting, lumen formation, anastomosis, pericyte recruitment, perfusion, and pruning of blood vessels.\"},{\"question\":\"What is illustrated in the accompanying figures?\",\"answer\":\"The figures show microscopy images of endothelial cell behavior in different matrices, flow cytometry data, and dose-response curves for drug testing, providing visual evidence of the experimental results.\"}]","2018-Nowak-Sliwinska-Angiogenesis | 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