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This study systematically reviews and meta-analyzes prevalence data to quantify pooled point, one-year, and lifetime estimates across general, clinical, and high-risk populations. Searches across major databases up to March 31, 2025 identify 150 studies with 8,960,338 individuals, providing global prevalence and subgroup differences. Random-effects models generate 25.92% pooled point prevalence, with higher estimates by sex, region, diagnostic approach, and associated risk factors.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/worldwide-prevalence-of-haemorrhoids-a-systematic-review-and-meta-analysis/455996/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/worldwide-prevalence-of-haemorrhoids-a-systematic-review-and-meta-analysis/455996.png","ImageObject",300,407,{"name":92,"@type":93},"Bintang","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main objective of the study on haemorrhoidal disease prevalence?","Question",{"text":112,"@type":113},"To systematically assess the global prevalence of haemorrhoidal disease using a systematic review and meta-analysis.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were prevalence estimates calculated in the meta-analysis?",{"text":117,"@type":113},"The pooled point prevalence of HD was analyzed with a random-effects model and reported with 95% confidence intervals.",{"name":119,"@type":110,"acceptedAnswer":120},"Which factors were associated with haemorrhoids in unadjusted analyses?",{"text":121,"@type":113},"Older age, obesity, pregnancy, diabetes, family history, constipation, and hypertension were associated with a higher likelihood of haemorrhoids.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},455996,1791255230,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":36,"preview_page_count":4},962085564381,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","AnnAls of Medicine  \n2026, Vol. 58, no. 1, 2606433  \n[https://doi.org/10.1080/07853890.2025.2606433](https://doi.org/10.1080/07853890.2025.2606433)  \nRESEARCH ARTICLE     \nWorldwide prevalence of haemorrhoids: a systematic review and meta-analysis  \nAmin Esmaeilnia Shirvania* , Kimia Pakdamanb* , Zahra Malekic , Soroush Soraneha , Fatemeh Rezaei cheginic , Kasra Pakdamand , Mohebat Valie , Hossein-Ali Nikbakhtf , Layla Shojaieg  and Pouyan Ebrahimib,h   \naschool of Medicine, Babol University of Medical sciences, Babol, iran; bcellular and Molecular Biology Research center, Health Research institute, Babol University of Medical sciences, Babol, iran; cshiraz University of Medical sciences, shiraz, iran; dschool of nursing and Midwifery, Mazandaran University of Medical sciences, sari, iran; eschool of Health, shiraz University of Medical sciences, shiraz, iran; fsocial determinants of Health Research center, Health Research institute, Babol University of Medical sciences, Babol, iran; gdivision of Gi/liver, department of Medicine, Keck school of Medicine, University of southern california, los Angeles, cA, UsA; hcancer Research center, Health Research institute, Babol University of Medical sciences, Babol, iran  \nABSTRACT  \nBackground: Haemorrhoidal disease (HD) is one of the most common anorectal disorders globally, significantly impacting individuals’ quality of life and productivity. Despite its importance, global prevalence remains unclear due to limited population-specific studies. This study aimed to systematically assess the global prevalence of HD through a systematic review and meta-analysis.  \nMethods: We conducted a systematic review and meta-analysis by searching PubMed, Scopus, Embase, Web of Science, and Google Scholar up to March 31, 2025, without language restrictions. Studies reporting prevalence of haemorrhoids in general, clinical, or high-risk populations were included. Exclusion criteria comprised studies lacking total sample size, focusing on other anorectal conditions, or using duplicate or insufficient data. Four independent reviewers extracted and appraised study quality using the Joanna Briggs Institute tool. The primary outcome was pooled point prevalence of HD, analyzed using a random-effects model with 95% confidence intervals (CIs). The study was registered in PROSPERO (CRD420251045600).  \nResults: From 6,312 records, 150 studies (210 datasets) comprising 8,960,338 individuals were included. The global pooled point prevalence was 25.92%(95% CI: 22.62–29.22). Lifetime prevalence was 27.19%(95% CI: 14.77–39.60), and one-year prevalence was 21.65%(95% CI: 14.33–28.97). Prevalence was higher in women (27.33%, 95% CI: 21.84– 32.82) than in men, and highest in the African region 28.07%(95% CI: 15.34–40.79). Invasive diagnostic methods (28.05%, 95% CI: 23.86–32.26) yielded higher prevalence estimates than non-invasive methods. Also, factors showing associations with HD in unadjusted analyses include older age, obesity, pregnancy, diabetes, family history, constipation, and hypertension.  \nConclusion: HD remains a prevalent condition globally, with minor variation across regions. The burden is consistent regardless of socioeconomic context. Diagnostic method and population characteristics influence prevalence estimates. These findings underscore the importance of targeted prevention and early intervention strategies, especially for at-risk groups.  \nKEY MESSAGES  \n1. This meta-analysis of 150 studies from 45 countries provides the most comprehensive global estimates of haemorrhoidal disease, with pooled point, one-year, and lifetime prevalences of 25.92%, 21.65%, and 27.19%, respectively.  \n2. Key risk factors identified include older age, obesity, pregnancy, diabetes, constipation, and family history, all of which were associated with a higher likelihood of developing haemorrhoids.  \nARTICLE HISTORY  \nReceived 30 May 2025 Accepted 12 December 2025  \nKEYWORDS  \nHaemorrhoids;  \nprevalence; haemorrhoid; epid","cbCaifmLaCGKuZZU","https://ap.wps.com/l/cbCaifmLaCGKuZZU","pdf",1611305,16,"English","# Abstract\n# Methods\n# Results\n# Conclusion\n# Key messages\n# Introduction","[{\"question\":\"What was the main objective of the study on haemorrhoidal disease prevalence?\",\"answer\":\"To systematically assess the global prevalence of haemorrhoidal disease using a systematic review and meta-analysis.\"},{\"question\":\"How were prevalence estimates calculated in the meta-analysis?\",\"answer\":\"The pooled point prevalence of HD was analyzed with a random-effects model and reported with 95% confidence intervals.\"},{\"question\":\"Which factors were associated with haemorrhoids in unadjusted analyses?\",\"answer\":\"Older age, obesity, pregnancy, diabetes, family history, constipation, and hypertension were associated with a higher likelihood of haemorrhoids.\"}]","Worldwide prevalence of haemorrhoids - a systematic review and meta-analysis | PDF",1790744880]