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list?",{"text":72,"@type":64},"The lineup spans areas including electrochemistry (e.g., adiponitrile electrosynthesis) and bacterial immunity (e.g., phage proteases activating CBASS antiphage immunity), alongside materials science and planetary science topics.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},510251,1791319398,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,127],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & 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sovereignty’ p. 22 Adiponitrile synthesis with nontoxic electrodes p. 91  \nPhage protease  \ntrip wires for bacterial defense p. 102  \n1 OCTOBER 2026 | VOLUME 394 | ISSUE 6819  \nSPECIAL ISSUE  \nWomen’s Health  \nILLUSTRAT ION: CHIARA VERCESI  \nINTRODUCTION  \n42 A lifelong focus on women’s health  \n—Y. Nusinovich et al.  \nPERSPECTIVES  \n44 Does the postmenopausal ovary still matter?  \nOvaries may influence health  \nlong after their reproductive function ends —M. B. Stout and F. E. Duncan  \nREVIEWS  \n46 Shaping maternal physiology: Immune control of reproductive adaptation  \n—D. Corral and Y. Belkaid  \n53 X andY chromosomes as determinants of aging and disease  \n—D. B. Dubal et al.  \n60 Reframing menopause and menopause hormone therapy as opportunities for healthy aging  \n—L. L. Gravelsins et al.  \nPODCAST  \n69 Sex-specific mechanisms of chronic pain  \n—A. Venkataraman et al.  \nWomen make up more than half the population, but most of what we know about women’s biology comes from extrapolation of studies in men. This has been changing in recent years, and this special issue highlights some of the progress in understanding the biological basis of sex differences in health and disease and medical issues relevant to women’s health across different stages of life. See the section beginning on page 42. Illustration: Chiara Vercesi  \nScience 1 OCTOBER 2026 3  \nCONTENTS  \nEDITORIAL  \n5 Keep AI-augmented science contestable —C. Trattner  \n7 Verification makes discovery matter —J. Bhattacharya  \nNEWS  \n12 First glowing cuttlefish marks a genetic engineering milestone  \nBreakthroughs in manipulating cephalopod embryos pave way for new studies of perception, brain evolution, and more—S. Reardon  \n14 Fed up with politicians not listening, a climate scientist runs for o􀀀ce  \nLuciana Gatti, who studies carbon uptake in the Amazon, aims to join Brazil’s lower house in 4 October elections—D. Grossman  \n15 U.K. funder used ‘AI triage’to reject grant proposals  \nResearchers raise privacy and fairness concerns following unexpected use of AI-based assessment—C. Offord  \n16 Can an AI feel pain? It can at least act like it does  \nStudy reignites debate over what, if anything, machines can feel  \n—T. Howarth  \n17 Oil wells could become mines for critical minerals  \nEngineered fluids could extract metals from low-grade ore in vast underground reservoirs tapped by fracking—P. Voosen  \n18 Project will track Amazon biodiversity in real time  \nLeaders of $100 million effort will use automated detection methods and computer models to monitor species’ trends—W. Cornwall  \n20 Space telescope will  \nreopen view of far-infrared sky  \nNASA’s $1.2 billion PRIMA will explore galaxy evolution and planetary birth—D. Clery  \n21 Impending changes to U.S. human subject protections put ethicists on edge  \nHHS plan to revise the Common Rule focuses on easing regulatory burden for lower risk studies  \n—S. Reardon  \nFEATURES  \n22 Shots on goal  \nCan Africa make 60% of its vaccines by 2040? That’s a tall order, as the travails of South African companies show—J. Cohen  \nCOMMENTARY  \nPERSPECTIVES  \n27 Self-assembling polymers work up some nerve  \nMicrometer-long peptide amphiphilefibrils enhance neuronal adhesion and function—S. Kumar RESEARCH ARTICLE p. 125  \n29 A mitochondrial carrier turns on the heat  \nAn orphan protein integrates circadian, dietary, and environmental signals to control brown fat metabolism—M. van der Laan RESEARCH SUMMARY p. 79  \n30 Osteoarthritis as avascular disease  \nHypertension worsens osteoarthritis and could be a therapeutic target inpatients with both conditions  \n—C. Wen and M. Ting Au RESEARCH SUMMARY p. 80  \n32 A tumor suppressor shuts down a signal gradient  \np53 shuts down the spatial signaling of a morphogen and prevents clonal cell expansion—D. Engelman and C. Blanpain  \nRESEARCH SUMMARY p. 78  \nPOLICY FORUM  \n33 Longevity products: Innovation through","cbCaisuKunfnKKq6","https://ap.wps.com/l/cbCaisuKunfnKKq6","pdf",41070640,190,"English","# Introduction\n## A lifelong focus on women’s health\n# Perspectives\n## Does the postmenopausal ovary still matter?\n## Sex-specific mechanisms of chronic pain\n# Reviews\n## Shaping maternal physiology\n## X and Y chromosomes as determinants of aging and disease\n## Reframing menopause and menopause hormone therapy\n# Podcast\n## Sex-specific mechanisms of chronic pain\n# Editorial and News\n## Keep AI-augmented science contestable\n## Verification makes discovery matter\n# Features and Commentary\n## Shots on goal\n## Longevity products: Innovation through regulation\n# Books and Letters\n## A medical mystery unfolds in middle America\n## Epistemic justice in gene-editing research\n# Research Highlights and Summaries\n## Cell biology and metabolism\n## Arthritis and biomaterials\n# Research Articles\n## Electrochemistry and bacterial immunity","[{\"question\":\"What central theme does the Women’s Health special issue emphasize?\",\"answer\":\"It highlights progress in understanding the biological basis of sex differences in health and disease, with medical issues relevant to women’s health across different stages of life.\"},{\"question\":\"Which topics are covered in the perspectives section?\",\"answer\":\"The issue includes discussions such as whether the postmenopausal ovary still matters and sex-specific mechanisms underlying chronic pain.\"},{\"question\":\"What research areas are featured in the research articles list?\",\"answer\":\"The lineup spans areas including electrochemistry (e.g., adiponitrile electrosynthesis) and bacterial immunity (e.g., phage proteases activating CBASS antiphage immunity), alongside materials science and planetary science topics.\"}]","Women’s Health - Special Issue - 1 October 2026 | PDF",1791239905,479]