[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-46241-en":3,"doc-seo-46241-105":30,"detail-sidebar-cat-0-en-105":91},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":21,"is_downloadable":21,"audit_status":21,"page_count":22,"language":23,"language_code":24,"site_id":25,"html_lang":24,"table_of_contents":26,"faqs":27,"seo_title":13,"seo_description":14,"update_tm":28,"read_time":29},46241,962075114101,"Seraphina","https://ap-avatar.wpscdn.com/avatar/e000253a75eb197efd?x-image-process=image/resize,m_fixed,w_180,h_180&k=1780044092746381165",7,"Healthcare","Why We Are Vaccinating Children Against COVID-19","The article examines COVID-19 inoculations for children, focusing on age-stratified mortality and the evidence base behind vaccine decisions. It reports that COVID-19-attributed deaths per capita are concentrated in the elderly with high comorbidities, while children show negligible levels, and similarly normalized post-inoculation deaths are small though not negligible. It critiques short, non-representative clinical trials with limited predictive power and lack of biomarker and long-term safety assessment. A conservative cost-benefit analysis suggests substantially more deaths attributable to each inoculation than to COVID-19 in the most vulnerable 65+ group, and argues age-dependent effects may worsen the ratio for younger populations.","i An update to this article is included at the end  \nToxicology Reports 8 (2021) 1665–1684  \nContents lists available at ScienceDirect Toxicology Reports  \njournal [homepage: www.elsevier.com/locate/toxrep](homepage: www.elsevier.com/locate/toxrep)  \n| Why are we vaccinating children against COVID-19? |  |  |  |\n| --- | --- | --- | --- |\n| Ronald N. Kostoff a, *, Daniela Calinab, Darja Kanduc c, Michael B. Briggs d, Panayiotis Vlachoyiannopoulos e, Andrey A. Svistunovf, Aristidis Tsatsakis g\u003Cbr>a Independent Consultant, Gainesville, VA, 20155, USA\u003Cbr>b Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349, Craiova, Romania\u003Cbr>c Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy\u003Cbr>d Independent Consultant, Roscommon, MI, 48653, USA\u003Cbr>e Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece\u003Cbr>f Department of Pharmacology, I.M.Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia g Department of Forensic Sciences and Toxicology, Faculty of Medicine, University of Crete, 71003, Heraklion, Greece |  |  |  |\n| A R T I C L E I N F O |  | A B S T R A C T |  |\n| Handling Editor: Dr. Konstantinos Poulas |  | This article examines issues related to COVID-19 inoculations for children. The bulk of the official COVID-19-attributed deaths per capita occur in the elderly with high comorbidities, and the COVID-19 attributed deaths per capita are negligible in children. The bulk of the normalized post-inoculation deaths also occur in the elderly with high comorbidities, while the normalized post-inoculation deaths are small, but not negligible, in children. Clinical trials for these inoculations were very short-term (a few months), had samples not representative of the total population, and for adolescents/children, had poor predictive power because of their small size. Further, the clinical trials did not address changes in biomarkers that could serve as early warning indicators of elevated predisposition to serious diseases. Most importantly, the clinical trials did not address long-term effects that, if serious, would be borne by children/adolescents for potentially decades.\u003Cbr>A novel best-case scenario cost-benefit analysis showed very conservatively that there are five times the number of deaths attributable to each inoculation vs those attributable to COVID-19 in the most vulnerable 65+ demographic. The risk of death from COVID-19 decreases drastically as age decreases, and the longer-term effects of the inoculations on lower age groups will increase their risk-benefit ratio, perhaps substantially. |  |\n| Keywords: COVID-19\u003Cbr>SARS-CoV-2\u003Cbr>Inoculation\u003Cbr>mRNA vaccines Viral vector vaccines Adverse events Vaccine safety |  |  |  |\n\n1. Introduction  \nCurrently, we are in the fifteenth month of the WHO-declared global COVID-19 pandemic. Restrictions of different severity are still in effect throughout the world [1]. The global COVID-19 mass inoculation is in its eighth month. As of this writing in mid-June 2021, over 800,000,000 people globally have received at least one dose of the inoculation and roughly half that number have been fully inoculated [2]. In the USA, about 170,000,000 people have received at least one dose and roughly 80 % of that number have been fully inoculated [2].  \nAlso, in the USA, nearly 600,000 deaths have been officially attributed to COVID-19. Almost 5,000 deaths following inoculation have been reported to VAERS by late May 2021; specifically, “Over 285 million doses ofCOVID-19 vaccines were administered in the United States from December 14, 2020, through May 24, 2021. During this time, VAERS received 4,863 reports of death (0.0017 %) among people who received  \na COVID-19 vaccine.” [3](the Vaccine Adverse Events Reporting System (VAERS) is a passive surveillance system managed jointly by the CDC and FDA [3]. Historically, VAERS has been shown ","cbCaiu8RsnDaYSRu","https://ap.wps.com/l/cbCaiu8RsnDaYSRu","pdf",1414927,3,1,22,"English","en",105,"# Introduction\n## COVID-19 inoculation rollout and surveillance metrics\n## Definitions and terminology used in the analysis\n## Prioritization of inoculations in the United States","[{\"question\":\"Why does the article focus on children’s COVID-19 inoculation outcomes?\",\"answer\":\"It analyzes issues specific to COVID-19 inoculations for children, emphasizing how mortality patterns and evidence quality differ by age group.\"},{\"question\":\"What mortality pattern does the article report across ages?\",\"answer\":\"COVID-19-attributed deaths per capita are described as largely occurring in elderly people with high comorbidities, while the article states deaths are negligible in children.\"},{\"question\":\"What limitations does the article identify in the clinical trials for these inoculations?\",\"answer\":\"The trials are characterized as very 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