[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-208904-105":59,"doc-detail-208904-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","vestibular-papillomatosis-a-differential-diagnosis-of-vulvar-condylomas","Vestibular papillomatosis - A differential diagnosis of vulvar condylomas","","Case letter describing vestibular papillomatosis (VP) initially misidentified as vulvar condyloma. A 25-year-old woman with genital papules underwent negative cervicovaginal smear and negative HIV/hepatitis B and C serologies; clinical and dermoscopic findings showed linear, symmetrical filiform papillae without acetic-acid whitening. The report explains evolving concepts linking VP to HPV as a minority relationship and contrasts VP with condyloma acuminata using clinical, dermoscopic, and acetic-acid test characteristics. Emphasis is placed on correct diagnosis to reassure patients and avoid unnecessary biopsies, laboratory testing, and invasive treatments.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/vestibular-papillomatosis-a-differential-diagnosis-of-vulvar-condylomas/208904/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/vestibular-papillomatosis-a-differential-diagnosis-of-vulvar-condylomas/208904.png","ImageObject",300,407,{"name":92,"@type":93},"Ezra","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-05",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",24,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the initial diagnosis and why was it reconsidered?","Question",{"text":113,"@type":114},"The patient’s genital papules were first diagnosed as vulvar condyloma by gynecologic evaluation. Dermatology confirmed vestibular papillomatosis based on characteristic clinical appearance, dermoscopy, and lack of acetic-acid whitening.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How do clinicians differentiate vestibular papillomatosis from condyloma acuminata?",{"text":118,"@type":114},"VP tends to show symmetrical or linear soft pinkish papillae with separated bases and typically does not bleach on the acetic acid test. Condyloma acuminata is usually hard and irregular, may cluster around a base, and more often whitens under acetic acid.",{"name":120,"@type":111,"acceptedAnswer":121},"Why is correct diagnosis important for patient management?",{"text":122,"@type":114},"Accurate recognition of vestibular papillomatosis helps reassure patients and prevents unnecessary laboratory tests, biopsies, and invasive or ablative treatments.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},208904,1788607111,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":130,"read_time":24},1099514068035,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Our Dermatology Online  \n Case Letter  \nVestibular papillomatosis: A differential diagnosis of vulvar condylomas  \nAsmae Abdelmouttalib, Sanae Sialiti, Mariame Meziane, Karima Senouci  \nDermatology and Venereology Department, Mohamed V University in Rabat, Morocco  \nCorresponding author: Asmae Abdelmouttalib, MD, [E-mail: abdelmouttalibasmae@gmail.com](E-mail: abdelmouttalibasmae@gmail.com)  \nSir,  \nFor a considerable time, vestibular papillomatosis (VP) has been conceived of as a secondary pathology to HPV (human papilloma virus) . Nowadays, several authors are reconsidering it as an anatomical variant of the vestibular mucosa. We report a case of VP initially mistaken for vulvar condyloma.  \nA 25-year-old female without any particular medical history presented herself to the gynecologist for genital papules, without functional signs of genital discharge or dyspareunia. A cervicovaginal smear and viral serologies for HIV and hepatitis B and C were negative, and a diagnosis of vulvar condyloma was reached. The patient was referred to the dermatology department for eventual treatment. A clinical examination revealed filiform, flexible, flesh-colored papillae 1–2 mm in diameter located on both edges of the vulva (Fig. 1) . A dermoscopic examination found linear, symmetrical papillae in the vulval vestibule with abundant vessels along them (Fig. 2) . There was no whitening of the lesions under the acetic acid test. The diagnosis of vestibular papillomatosis was reached, the patient was reassured, and no treatment was prescribed.  \nAt the beginning of the eighties, authors linked the occurrence of VP to an HPV infection based on histological and/or molecular evidence of the presence of the virus and considered VP to be responsible for many cases of pruritus and/or vulvodynia. Based on these findings, a number of clinicians have treated this condition with laser ablation or topical application of podophyllin or trichloroacetic acid [1]. Currently, several studies have shown the rare relationship between HPV infection and VP. VP is thus considered an anatomical  \nFigure 1: Filiform, flesh-colored papillae on the lateral edges of the vulva.  \nvariant of the vestibular mucosa [2]. Papillae are generally distinguishable from condyloma acuminata by clinical and dermoscopic examination, without the need for biopsies or HPV testing [1] . Clinical criteria have been proposed to assist in the differential diagnosis between VP and condyloma acuminata. In VP, the papillae are symmetrical or linear, soft and pinkish. Their bases are separated, unlike acuminate condylomata, which are hard and irregular and whose projections may cluster around the same base. In addition, most acuminate condylomata bleach under the acetic acid test [3] . Dermoscopy of VP shows abundant and irregular vessels along the center of cylindrical papillae. In addition, inacuminate condyloma, irregular projections with tapered ends are found, which are clearer and wider than in VP. Hemorrhages in the form of red dots or streaks may also be present [4]. No ablative treatment is usually necessary in the case of VP even in the presence of concomitant symptomatology or molecular HPV infection [1] .  \nHow to cite this article: Abdelmouttalib A, Sialiti S, Meziane M, Senouci K. Vestibular papillomatosis: A differential diagnosis of vulvar condylomas. Our Dermatol Online. 2022;13(3):344-345 .  \nSubmission: 21.12.2020; Acceptance: 06.03.2021  \nDOI: 10.7241/ourd.20223.34  \n© Our Dermatol Online 3.2022 344  \n[www.odermatol.com](www.odermatol.com)  \nFigure 2: Profuse and irregular vascular channels in the transparent core of multiple, cylindrical filiform projections, with the bases of the individual projections remaining separate.  \nVestibular papillomatosisis an entity that dermatologists should be aware of. Correct diagnosis helps to reassure patients and avoid unnecessary laboratory tests, biopsies, and invasive treatments.  \nConsent  \nThe examination of the patient was conducted a","cbCaibgSH6pTLkPY","https://ap.wps.com/l/cbCaibgSH6pTLkPY","pdf",602436,"English","# Our Dermatology Online - Case Letter\n## Clinical presentation and initial diagnosis\n## Dermoscopic and acetic-acid findings\n## Background: relationship with HPV and treatment history\n## Differential diagnosis criteria vs condyloma acuminata\n## Clinical implications and patient reassurance\n## Consent and publication details\n## References","[{\"question\":\"What was the initial diagnosis and why was it reconsidered?\",\"answer\":\"The patient’s genital papules were first diagnosed as vulvar condyloma by gynecologic evaluation. Dermatology confirmed vestibular papillomatosis based on characteristic clinical appearance, dermoscopy, and lack of acetic-acid whitening.\"},{\"question\":\"How do clinicians differentiate vestibular papillomatosis from condyloma acuminata?\",\"answer\":\"VP tends to show symmetrical or linear soft pinkish papillae with separated bases and typically does not bleach on the acetic acid test. Condyloma acuminata is usually hard and irregular, may cluster around a base, and more often whitens under acetic acid.\"},{\"question\":\"Why is correct diagnosis important for patient management?\",\"answer\":\"Accurate recognition of vestibular papillomatosis helps reassure patients and prevents unnecessary laboratory tests, biopsies, and invasive or ablative treatments.\"}]","Vestibular papillomatosis - A differential diagnosis of vulvar condylomas | PDF"]