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Methods: A prospective observational study in 11 hospitals in Australia and New Zealand via the PREDICT network (April 2021–December 2023) enrolled children aged 0–\u003C18 with suspected sepsis. Findings: 6,232 children were included; 6232. Vasoactive agents were administered to 179 (2.9%) children overall, with detailed collection of treatment sequence and factors shaping initial selection.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/vasoactive-drug-use-in-children-with-community-acquired-septic-shock-in-australia-and-new-zealand/435425/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/vasoactive-drug-use-in-children-with-community-acquired-septic-shock-in-australia-and-new-zealand/435425.png","ImageObject",300,407,{"name":92,"@type":93},"SANS","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-08","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the study background regarding vasoactive agents in children with sepsis?","Question",{"text":113,"@type":114},"Vasoactive agents are described as critical supportive therapy for children with sepsis. The study focuses on describing how they are chosen and used.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the study conducted and where did it take place?",{"text":118,"@type":114},"It was a prospective observational study conducted in 11 hospitals across Australia and New Zealand through the PREDICT network from April 2021 to December 2023.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the key results about the use of vasoactive agents?",{"text":122,"@type":114},"Among 6,232 children with suspected sepsis, vasoactive agents were used in 179 (2.9%) children overall, and outcomes such as in-hospital mortality were reported.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},435425,1791325732,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090760505,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Articles  \nVasoactive drug use in children with community acquired septic shock in Australia and New Zealand  \nElliot Long,a,b,c,d,∗ Stephen Hearps,b,d Amanda Williams,b Ben Gelbart,b,d,e Warwick Butt,b,d,e Thomas Rozen,b,c,d,e Sarah McNab,b,c,f Meredith L. Borland,g,h Simon Erickson,i Shefali Jani,j,k Marino Festa,k,l Eunicia Tan,m,n Natalie Phillips,o,p Sainath Raman,p,q Amit Kochar,r,s Subodh Ganu,s,t Simon Craig,b,u,v Anna Lithgow,w Arjun Rao,x,y Emma Whyte,z,aa Stuart R. Dalziel,ab,ac Shane George,p,ad,ae Fran Balamuth,af,ag Scott L. Weiss,af,ah Nathan Kuppermann,ag,ai and Franz E. Babl,a,b,c,d On behalf of the Paediatric Research in Emergency Departments International Collaborative (PREDICT) network  \naDepartment of Emergency Medicine, The Royal Children’s Hospital, Parkville, Victoria, Australia bClinical Sciences, Murdoch Children’s Research Institute, Parkville, Victoria, Australia  \ncDepartment of Paediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Parkville, Victoria, Australia dDepartment of Critical Care, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Parkville, Victoria, Australia  \nePaediatric Intensive Care Unit, The Royal Children’s Hospital, Parkville, Victoria, Australia fDepartment of General Medicine, The Royal Children’s Hospital, Parkville, Victoria, Australia gDepartment of Emergency Medicine, Perth Children’s Hospital, Nedlands, Western Australia, Australia  \nhDivisions of Emergency Medicine and Paediatrics, School of Medicine, University of Western Australia, Perth, Western Australia, Australia iPaediatric Intensive Care Unit, Perth Children’s Hospital, Nedlands, Western Australia, Australia  \njDepartment of Emergency Medicine, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia kFaculty of Medicine and Health, University of Sydney, Camperdown, New South Wales, Australia  \nlPaediatric Intensive Care Unit, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia mMiddlemore Hospital, Auckland, New Zealand  \nnDepartment of Surgery, The University of Auckland, Auckland, New Zealand  \noEmergency Department, Queensland Children’s Hospital, Brisbane, Queensland, Australia  \npChildren’s Intensive Care Research Program, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia qPaediatric Intensive Care Unit, Queensland Children’s Hospital, Brisbane, Queensland, Australia  \nrDepartment of Emergency Medicine, Women and Children’s Hospital, Adelaide, South Australia, Australia sDepartment of Acute Care Medicine, University of Adelaide, Adelaide, South Australia, Australia tPaediatric Intensive Care Unit, Women and Children’s Hospital, Adelaide, South Australia, Australia uPaediatric Emergency Department, Monash Medical Centre, Monash Health, Clayton, Victoria, Australia vDepartment of Paediatrics, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia wDepartment of Paediatrics, Royal Darwin Hospital, Tiwi, Northern Territory, Australia  \nxDepartment of Emergency Medicine, Sydney Children’s Hospital, Randwick, New South Wales, Australia  \nySchool of Women’s and Children’s Health, University of New South Wales, Kensington, New South Wales, Australia zDepartment of Emergency Medicine, Townsville Hospital, Douglas, Queensland, Australia  \naaDepartment of Medicine and Dentistry, James Cook University, Douglas, Queensland, Australia abChildren’s Emergency Department, Starship Children’s Hospital, Auckland, New Zealand  \nacDepartment of Surgery and Paediatrics: Child and Youth Health, The University of Auckland, Auckland, New Zealand adDepartment of Emergency Medicine and Children’s Critical Care, Gold Coast University Hospital, Southport, Queensland, Australia aeSchool of Medicine and Dentistry, Griffith University, Southport, Queensland, Australia  \nafDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, Uni","cbCaipbhVmRFGWs6","https://ap.wps.com/l/cbCaipbhVmRFGWs6","pdf",2059740,"English","# Summary\n## Background\n## Methods\n## Findings","[{\"question\":\"What is the study background regarding vasoactive agents in children with sepsis?\",\"answer\":\"Vasoactive agents are described as critical supportive therapy for children with sepsis. The study focuses on describing how they are chosen and used.\"},{\"question\":\"How was the study conducted and where did it take place?\",\"answer\":\"It was a prospective observational study conducted in 11 hospitals across Australia and New Zealand through the PREDICT network from April 2021 to December 2023.\"},{\"question\":\"What were the key results about the use of vasoactive agents?\",\"answer\":\"Among 6,232 children with suspected sepsis, vasoactive agents were used in 179 (2.9%) children overall, and outcomes such as in-hospital mortality were reported.\"}]","Vasoactive drug use in children with community acquired septic shock in Australia and New Zealand | PDF",1790673569,23]