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A cross-sectional observational study enrolled 283 adults older than 40 years. Left calcaneum QUS using 500 kHz ultrasound frequency pulse penetration determined T-scores, estimating osteopenia prevalence and its predictors. QUS showed effectiveness, especially in older symptomatic patients, without ionizing radiation.",{"@graph":69,"@context":126},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/utilization-of-quantitative-ultrasound-methods-for-bone-mass-density-measurement-in-general-population-an-observational-study/449888/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/utilization-of-quantitative-ultrasound-methods-for-bone-mass-density-measurement-in-general-population-an-observational-study/449888.png","ImageObject",300,407,{"name":92,"@type":93},"dawugda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118,122],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main goal of this study?","Question",{"text":112,"@type":113},"To assess whether quantitative ultrasound of the calcaneum can be used to measure bone mass density and detect osteopenia as an alternative to DEXA in the general population.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the QUS test performed?",{"text":117,"@type":113},"The study used left calcaneum QUS with a 500 kHz ultrasonic frequency using the ultrasound pulse penetration method to calculate T-scores.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the key findings regarding osteopenia?",{"text":121,"@type":113},"Osteopenia prevalence was slightly higher in females than males. 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The availability ofcentral DEXAis not uniform in many countries; hence, a reliable, cheap, portable handy equipment is needed. Role of QUS as an alternative toDEXA has been studied for selective population but avery few studies have attemptedits utility in the general population forroutineuse.  \nMaterials and Methods: The cross-sectional observational study was done with 283patients with age more than40 years with both sexes. Any patient with a history of trauma, infection, surgical infection or immobilization of the lower limb for more than 6 weeks in the preceding 1 year. The left calcaneum was used for calculating T-score by QUS by utilizing 500 kHz ultrasonic frequency for the ultrasound pulse penetration method.  \nResults: The mean age of the study population was 51.4 ± 10.54years with 188 female and 95 males. The prevalence of osteopeniawas slightly higher among the female population (68.6%) in the current study group in comparison to males (54.7%). The age and symptomsofosteopenia werethe two variableswhich significantlydetermined the predictive power of QUSin diagnosing osteopenia.  \nConclusion: The use ofcalcaneum QUS proved to be a rapid and efficient method for assessing bone mass density, demonstrating its ability to detect osteopenia, especially in older and symptomatic patients. Given its cost-effectiveness, portability, and safety duetothe absence of ionizing radiation, QUS serves as a valuable and attractive alternative for initial bone health assessment, particularly in settings with limited access to central DEXA.  \nKeyword: Quantitative ultrasound, bone mineral density, dual-energy X-ray absorptiometry, calcaneum.  \nIntroduction  \nOsteoporosis is caused by disorientation of bone tissue microarchitecture, causing decrease in bone strength, resulting in increased risk of fracture. These fractures increase morbidity and mortality of the elderly population and are commonly due to hip  \nand spine fractures. The early diagnosis and use of Food and Drug Administration-approved drugs can increase the bone mass density and hence can reduce the risk of fracture [1]. The current diagnostic protocol employs either clinical diagnosis by documenting fracture of spine/hip following trivial trauma or  \n\n| \u003Cbr>Access this article online\u003Cbr>\u003Cbr>Website: [www.jocr.co.in](www.jocr.co.in)\u003Cbr>\u003Cbr>DOI:\u003Cbr>[https://doi.org/10.13107/jocr.2025.v15.i12.6568](https://doi.org/10.13107/jocr.2025.v15.i12.6568) | Author’s Photo Gallery |  |  |  |  |  |\n| --- | --- | --- | --- | --- | --- | --- |\n|  | | | | | | |\n|  |  |  |  |  | Dr. Sudhir Shyam Dr. Ajay Bharti\u003Cbr>Kushwaha |  |\n|  | \u003Cbr>1Department of Orthopedics, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.\u003Cbr>Address of Correspondence:\u003Cbr>Dr. Nitish Kumar,\u003Cbr>Department of Orthopedics, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India. [E-mail:](E-mail: nitishaiims@gmail.com)[ nitishaiims@gmail.com](E-mail: nitishaiims@gmail.com) |  |  |  |  |  |\n| Submitted: 23/09/2025; Review: 07/10/2025; Accepted: November 2025; Published: December 2025 |  |  |  |  |  |  |\n| DOI: [https://doi.org/10.13107","cbCaij7UX8UmUfUZ","https://ap.wps.com/l/cbCaij7UX8UmUfUZ","pdf",6062223,"English","# Introduction\n# Materials and Methods\n# Results\n# Conclusion\n# Keyword","[{\"question\":\"What is the main goal of this study?\",\"answer\":\"To assess whether quantitative ultrasound of the calcaneum can be used to measure bone mass density and detect osteopenia as an alternative to DEXA in the general population.\"},{\"question\":\"How was the QUS test performed?\",\"answer\":\"The study used left calcaneum QUS with a 500 kHz ultrasonic frequency using the ultrasound pulse penetration method to calculate T-scores.\"},{\"question\":\"What were the key findings regarding osteopenia?\",\"answer\":\"Osteopenia prevalence was slightly higher in females than males. Age and symptoms of osteopenia significantly determined the predictive power of QUS for diagnosing osteopenia.\"},{\"question\":\"Why is QUS considered attractive for clinical use?\",\"answer\":\"It is rapid and efficient and offers cost-effectiveness, portability, and safety due to the absence of ionizing radiation, supporting initial bone health assessment where central DEXA is limited.\"}]","Utilization of Quantitative Ultrasound Methods for Bone Mass Density Measurement in General Population - An Observational Study | PDF",1790731422,13]