[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-32608":3,"doc-seo-32608":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},32608,16904993612988,"Olivia Brown","https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd",7,"Healthcare","Utility of repeated antinuclear antibody tests: a retrospective database study","Anti-nuclear antibody (ANA) testing is commonly used for diagnosis and screening in patients with inflammatory or musculoskeletal symptoms, but the benefit of repeating ANA tests is unclear. This retrospective cohort study assessed the frequency, utility, and cost of repeat ANA testing using Australian multisite tertiary network data over seven years, evaluating the positive predictive value of a repeat test for ANA-associated rheumatologic conditions. Repeat ANA after a negative result showed low utility with high cost implications.","cbCaik8anpn9sEGZ","https://ap.wps.com/l/cbCaik8anpn9sEGZ","pdf",714214,1,6,"English","en","# Summary\n## Background\n## Methods\n## Findings\n## Interpretation\n# Introduction","[{\"question\":\"What was the study’s main objective regarding repeated ANA testing?\",\"answer\":\"To assess the positive predictive value of a repeat ANA test for diagnosing rheumatological conditions associated with ANA.\"},{\"question\":\"How were repeat ANA tests evaluated in the study?\",\"answer\":\"Researchers analyzed retrospective data from a multisite tertiary health network in Australia and identified patients whose ANA result changed from negative to positive on repeat testing, using a positive titre cutoff of 1:160.\"},{\"question\":\"What did the study conclude about repeating ANA tests after a negative result?\",\"answer\":\"Repeat ANA testing after a negative result has low utility and leads to high cost, with very few new diagnoses observed.\"}]",1781738785,15,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"utility-of-repeated-antinuclear-antibody-tests-a-retrospective-database-study","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/healthcare/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/utility-of-repeated-antinuclear-antibody-tests-a-retrospective-database-study/32608/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-06-17",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"What was the study’s main objective regarding repeated ANA testing?","Question",{"text":73,"@type":74},"To assess the positive predictive value of a repeat ANA test for diagnosing rheumatological conditions associated with ANA.","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"How were repeat ANA tests evaluated in the study?",{"text":78,"@type":74},"Researchers analyzed retrospective data from a multisite tertiary health network in Australia and identified patients whose ANA result changed from negative to positive on repeat testing, using a positive titre cutoff of 1:160.",{"name":80,"@type":71,"acceptedAnswer":81},"What did the study conclude about repeating ANA tests after a negative result?",{"text":82,"@type":74},"Repeat ANA testing after a negative result has low utility and leads to high cost, with very few new diagnoses observed.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]