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Thirty PEA procedures were performed in 26 participants, with two independent radiologists comparing contrast distribution across intracanal and foraminal regions. Reproducibility was assessed using intraclass correlation coefficients, and symptom relief at 1 month was analyzed.",{"@graph":14,"@context":71},[15,34,54],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & 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was the main purpose of the pilot study?","Question",{"text":61,"@type":62},"To evaluate the association between PEA outcomes and cone-beam computed tomography-reformatted epidurography (CBCT-RE).","Answer",{"name":64,"@type":59,"acceptedAnswer":65},"How were image findings compared between CBCT-RE and conventional epidurography (CE)?",{"text":66,"@type":62},"Two independent radiologists categorized and recorded contrast occurrence in specified intracanal ventral/extraforaminal regions on CE and in dorsal/ventral canal and dorsal/ventral foramen regions on CBCT-RE.",{"name":68,"@type":59,"acceptedAnswer":69},"What conclusion did the study reach about predicting PEA outcomes?",{"text":70,"@type":62},"CBCT-RE identifying contrast distribution patterns was useful for predicting the outcome of 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percutaneous epidural adhesiolysis: A pilot study  \nHao-Lun Kaoa, Guo-Shu Huanga,b, Chi-Tun Tangc, Fu-Chi Yangd, Kuo-Hua Chaoe, Han-Bin Huangf, Yi-Chih Hsua,*  \naDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; bDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; cDepartment of Neurosurgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; dDepartment of Neurology, TriService General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; eDepartment of Orthopedics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; fSchool of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC  \nAbstract  \nBackground: Conventional epidurography (CE) is thought to have insufficient usefulness on percutaneous epidural adhesiolysis (PEA) . We aimed to evaluate the association between the outcome of PEA and cone-beam computed tomography-reformatted epidurography (CBCT-RE) .  \nMethods: After ethics board approval and written informed consent were obtained, we performed 30 PEA in 26 participants, and evaluated their post-PEA image findings. Two independent radiologists categorized and recorded the occurrence of contrast in the intracanal ventral and extraforaminal regions on CE, and in the dorsal canal (DC), ventral canal (VC), dorsal foramen (DF), and ventral foramen (VF) on CBCT-RE. Reproducibility was assessed using intraclass correlation coefficients (ICCs) . Baseline characteristics along with contrast distribution patterns of CE and CBCT-RE were analyzed in terms of their association with symptom relief at 1 month after PEA.  \nResults: The rate of patients with symptoms relief >50% after PEA was 63.3% . The inter-reader agreement was higher for CBCT-RE (ICC = 0.955) than for CE (ICC = 0.793) . Participants with contrast coexisting in VC and DF adjacent to the irritated nerve root on CBCT-RE (p = 0 .015) had a significantly better response after PEA than those without contrast at these locations on CBCT-RE, independent of baseline characteristics (adjusted odds ratio: 11.414 [p = 0.012]) .  \nConclusion: CBCT-RE with identifying contrast distribution patterns is useful for predicting outcome of PEA.  \nKeywords: Cone-beam computed tomography-reformatted epidurography; Conventional epidurography; Failed back surgery syndrome; Percutaneous epidural adhesiolysis; Spinal stenosis  \n1. INTRODUCTION  \nPercutaneous epidural adhesiolysis (PEA) is performed to treat failed back surgery syndrome (FBSS) and spinal stenosis (SS) that are refractory to more conventional treatments, such as epidural steroid injections.1,2 There is strong evidence for the short-term (\u003C3 months) and moderate evidence for the mid-tolong-term (>3 months) efficacy of PEA.3 As the rate of spinal surgery continues to rise, PEA has emerged as a popular treatment for FBSS.  \n* Address correspondence. Dr. Yi-Chih Hsu, Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, 325, Section 2, Chenggong Road, Taipei 114, Taiwan, [ROC. E-mail address: doc31578@gmail.com](ROC. E-mail address: doc31578@gmail.com) (Y.-C. Hsu).  \nConflicts of interest: The authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article.  \nJournal of Chinese Medical Association. (2024) 87: 131-137.  \nReceived April 29, 2023; accepted September 12, 2023. doi: 10. 1097/JCMA.0000000000001024  \nCopyright © 2023, the Chinese Medical Association. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/](http://creativecommons.org/licenses/)[ ](http://creativecommons.org/licenses/)[by-nc-nd/4.0/](by-nc-nd/4.0/))  \nIn participants with FBSS and SS, conventional epiduro","cbCaislpKpkzD17l","https://ap.wps.com/l/cbCaislpKpkzD17l","pdf",727464,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion\n# Introduction\n# Methods\n## Participant selection","[{\"question\":\"What was the main purpose of the pilot study?\",\"answer\":\"To evaluate the association between PEA outcomes and cone-beam computed tomography-reformatted epidurography (CBCT-RE).\"},{\"question\":\"How were image findings compared between CBCT-RE and conventional epidurography (CE)?\",\"answer\":\"Two independent radiologists categorized and recorded contrast occurrence in specified intracanal ventral/extraforaminal regions on CE and in dorsal/ventral canal and dorsal/ventral foramen regions on CBCT-RE.\"},{\"question\":\"What conclusion did the study reach about predicting PEA outcomes?\",\"answer\":\"CBCT-RE identifying contrast distribution patterns was useful for predicting the outcome of PEA.\"}]","Usefulness of cone-beam computed tomography-reformatted epidurography in percutaneous epidural adhesiolysis: A pilot study | PDF",1790676519,18]