[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-447303-105":59,"doc-detail-447303-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","usabo-17-open-exam-final","USABO 17 Open Exam Final","","USABO Open Exam February 7 to 17, 2017 covers biology and chemistry concepts through eleven multiple-choice problems. Topics include viral structure and packaging via the pac site, Zika diagnostics and classical antibody production by plasma cells, identifying whether an unknown structure is a carbohydrate, lipid, or nucleic acid, and ligand sensitivity using receptor binding parameters. Additional questions address lymphocyte and cell receptor expression effects, equilibrium product ratios from Gibbs free energy, halophile salt tolerance strategies, NADPH oxidase subcellular localization in neutrophils, and HIV life-cycle accuracy, concluding with cancer drivers and C3 versus C4 plant comparisons.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":20,"@type":76,"position":81},"https://docshare.wps.com/document/exam/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/usabo-17-open-exam-final/447303/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/usabo-17-open-exam-final/447303.png","ImageObject",300,407,{"name":92,"@type":93},"Muffet","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-23","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Which amino acids are expected to interact with the viral genome’s pac site during capsid assembly?","Question",{"text":113,"@type":114},"The correct choice is the one that matches the amino acids predicted to be on the capsomere domain interacting with the pac site.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Why are Zika diagnostics difficult when antibodies from other flaviviruses are present?",{"text":118,"@type":114},"Antibodies generated from prior immune responses can cross-react with Zika antigens, causing diagnostics to misattribute exposure.",{"name":120,"@type":111,"acceptedAnswer":121},"At equilibrium, how does a positive vs. negative Gibbs free energy affect the product-to-reactant ratio?",{"text":122,"@type":114},"A reaction with more favorable (more negative) ΔG has a higher ratio of products to reactants at equilibrium, while a positive ΔG corresponds to a lower ratio.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},447303,1790969569,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":19,"category_name":20,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":36},962090768927,"https://ap-avatar.wpscdn.com/davatar_085a072bc5b1113ac321206ff7593b45","USABO Open Exam February 7 to 17, 2017  \n1. A virus has been discovered. The virus has no envelope and consists of a helical capsid surrounding its dsDNA genome. During assembly, the pac site of the genome ensures that it is properly packaged by the capsomeres. Which of the following amino acids is/are expected to be on the capsomere domain that interacts with the pac site?  \nA. Lysine.  \nB. Methionine.  \nC. Glycine.  \nD. Arginine.  \nE. A and D.  \n2. Developing diagnostics for the Zika virus has proven to be difficult due to cross reactivity displayed by antibodies for other flaviviruses. If a person has been previously exposed to certain flaviviruses (i.e. yellow fever or West Nile virus), then he/she may have antibodies which diagnostics erroneously attribute to Zika virus exposure. The issue stems from antibodies that resulted from a prior immune response. In the classic immune response, which cells are primarily responsible for the production of antibodies?  \nA. Macrophages.  \nB. Eosinophils.  \nC. Plasma cells.  \nD. T lymphocytes.  \nE. Goblet cells.  \n3. The structure shown is an example of a(n)…(Select the BEST answer.)  \nA. Carbohydrate.  \nB. Lipid.  \nC. Nucleic acid.  \nD. Saturated lipid.  \nE. Unsaturated lipid.  \n4. You are analyzing a receptor that is expressed on the cell surface of two different cell types (Cell  \nType I and Cell Type II). Based on the information given in the table below, identify the cell type whose receptor is more sensitive to the ligand?  \n\n|  | K1 (µM-1/min) |\n| --- | --- |\n| Cell Type 1 | 8 |\n| Cell Type 2 | 16 |\n\nA. Cell Type 1 is more sensitive, because its kD is larger.  \nB. Cell Type 1 is more sensitive, because its kD is smaller.  \nC. Cell Type 2 is more sensitive, because its kD is larger.  \nD. Cell Type 2 is more sensitive, because its kD is smaller.  \n5. You are observing the response of Type 1 and Type 2 cells to a specific protein ligand. Type 1 cells proliferate rapidly in response to the ligand unlike Type 2 cells. Circle the option(s) from below that can explain the observed difference.  \nA. The gene encoding the ligand specific receptor in Type 1 cells has a methylated promoter  \nB. Type 1 cells express intracellular receptors unlike Type 2 cells.  \nC. Type 1 cells express plasma membrane receptors unlike Type 2 cells.  \nD. Type 1 cells lack the transcription factor needed for the expression of the gene encoding the ligand specific receptor.  \nE. The gene encoding the ligand specific membrane receptor in Type 1 cells has a frame-shift mutation that generates a premature stop codon.  \n6. The following reactions are the free energy changes associated with four biological reactions. Which reaction will have the highest ratio of products to reactants at equilibrium?  \nA. ΔG = -2.5 Kcal/mole.  \nB. ΔG = -1.5 Kcal/mole.  \nC. ΔG = +2.5 Kcal/mole.  \nD. ΔG = +1.0 Kcal/mole.  \n7. Which of the following is a plausible reason that explains why extreme halophiles can tolerate high salt conditions?  \nA. They can accumulate compatible solutes, such as glycerol and sucrose, in their cytoplasm.  \nB. They can prevent the entrance of protons in their cytoplasm.  \nC. They have less porins or transport proteins, which makes them less permeable to solutes.  \nD. They have more saturated fatty acids in their membranes than unsaturated fatty acids.  \nE. They have more unsaturated fatty acids in their membranes than saturated fatty acids.  \n8. NADPH oxidase is a complex of five proteins that forms (not hydrolyzes) reactive oxygen species such as O2-- and H2O2 by catalyzing the reduction of oxygen (O2) by hydride ions (H--) from NADPH. Loss of function mutations in NADPH oxidase components were found in the 1950-60’sto underlie an inherited human immunodeficiency disorder called chronic granulomatous disease (CGD) . CGD is characterized by the inability of neutrophils to destroy phagocytosed bacteria, especially if the bacteria are capable of hydrolyzing H2O2. Based on your knowledge of phagocytosis by imm","cbCaindwLhfVSpkF","https://ap.wps.com/l/cbCaindwLhfVSpkF","pdf",1039814,16,"English","# Question Set\n## 1-11 Biology and Biochemistry Questions","[{\"question\":\"Which amino acids are expected to interact with the viral genome’s pac site during capsid assembly?\",\"answer\":\"The correct choice is the one that matches the amino acids predicted to be on the capsomere domain interacting with the pac site.\"},{\"question\":\"Why are Zika diagnostics difficult when antibodies from other flaviviruses are present?\",\"answer\":\"Antibodies generated from prior immune responses can cross-react with Zika antigens, causing diagnostics to misattribute exposure.\"},{\"question\":\"At equilibrium, how does a positive vs. negative Gibbs free energy affect the product-to-reactant ratio?\",\"answer\":\"A reaction with more favorable (more negative) ΔG has a higher ratio of products to reactants at equilibrium, while a positive ΔG corresponds to a lower ratio.\"}]","USABO 17 Open Exam Final | PDF",1790719708]