[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-213122-en":3,"doc-seo-213122-105":30,"detail-sidebar-cat-0-en-105":83},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},213122,4398048949847,"Eliana","https://ap-avatar.wpscdn.com/avatar/400002536579ef2da7f?_k=1778318612642679267",7,"Healthcare","Urodynamic and Clinical Perspectives of Overactive Bladder in Women - Prospective Diagnostic Algorithm and Symptom/Urodynamic Evaluation","Urodynamic measures of overactive bladder (OAB) in women were examined using a standardized diagnostic work-up to clarify underlying motor or sensory pathophysiology. A prospective evaluation selected uniform OAB cases with detailed exclusion criteria, reducing the sample to 35. Participants underwent a 3-day voiding diary, 24-hour pad-weight testing, and validated symptom/discomfort questionnaires, followed by conventional urodynamic studies. OAB with detrusor overactivity showed higher sensory filling cystometry measures and higher maximum detrusor and vesical pressures. Among questionnaires, OAB-V8 related most to detrusor overactivity.","362  \nDokmeci F 1 , Cetinkaya S E 1 , Yuce T 1 , Gok H2  \n1. Ankara University, School of Medicine, Dept. of OB and GYN, 2. Ankara University, School of Medicine, Dept. of Physical Therapy and Reh.  \nURODYNAMIC AND CLINICAL PERSPECTIVES OF OVERACTIVE BLADDER IN WOMEN  \nHypothesis / aims of study  \nUrodynamic measures of overactive bladder (OAB) in women selected through a standardized diagnostic work-up represent the underlying motor or sensorial pathophysiology more precisely. We performed this study in order to test the above hypothesis. First, we set forth a prospective diagnostic algorithm , then we selected the unbiased and uniform OAB cases, and finally investigated the well-defined OAB in women from both symptomatic and urodynamic perspective with clinical and urodynamic measures. We aimed to emphasize the importance of this three-step approach as the basic study design for OAB, which may lead to further well-structured and reliable research.  \nStudy design, materials and methods  \nWe prospectively evaluated women with OAB symptoms. Although the definition of OAB was standardized by ICS as “urgency with or without urge incontinence, usually with frequency and nocturia”, its underlying pathophysiology still remains unclear. Moreover, many different causes of urgency are grouped together as OAB, which creates clinical confusion [1] . To overcome the lack of uniformity for the definition of symptoms as well as the other urgency related conditions, which are frequently mentioned as the major problem in such studies, detailed exclusion criteria are established The solid number of the patients is decreased to 35, whom hold the common clinical OAB characteristics (Fig. 1) . After the diagnostic work-up, patients with uniform OAB symptoms and findings (n=35) were investigated by recording 3-day voiding diary, 24hr pad-weight test. In addition, UDI-6, IIQ-7, Wagner and Overactive Bladder-Validated 8 Question Awareness Tool (OAB-V8) [3] Questionnaires were used for the evaluation of patient discomfort. The women also underwent conventional urodynamic studies including filling cystometry and pressure flow studies, conformed to International Continence Society (ICS) recommended good urodynamic practice guidelines. Relation between the OAB cases, grouped accordingly with the presence of detrusor overactivity is investigated in terms of urodynamic measures representing motor or sensorial pathophysiology. Statistical analysis was performed using the software SPSS (version 13, Chicago, IL, USA) . The Student’s t test and the Mann–Whitney U test were used as appropriate. P values \u003C 0.05 were considered significant.  \nResults  \nUrodynamic findings including filling cystometry and uroflowmetry measures were compared among the two groups in terms of presence or absence of detrusor overactivity (OAB with DOA n=15, OAB without DOA n=20) . In the OAB group without DOA, sensorial measures of filling cystometry (first sensation, normal sensation, strong sensation and max. cystometric capacity) were found significantly higher compared to the OAB group with DOA (p= 0,001, p=0,011, p= 0,003, p= 0,003 respectively) . Max. detrusor pressure and max. vesical pressure were also found to be significantly higher (p\u003C0,001 and p=0,001 respectively) . Among all three questionnaires, OAB-V8 was found to be more related with urodynamic measures in terms of detrusor overactivity.  \nInterpretation of results  \nThe urodynamic measures of filling cystometry showed variances within the descriptive categories of motor or sensorialoveractive bladder. Comparatively for the OAB group with DOA, max detrusor and vesical pressures and in OAB group without DOA sensorial urodynamic measures are found to be significantly higher , similarly with the literature [2] .  \nConcluding Message  \nSelection of unbiased and uniform cases of OAB for further studies may improve the understanding of the underlying pathophysiology.  \nFigure 1: Diagnostic algorithm for OAB Syndrome.  \nTab","cbCailXiANh5tld1","https://ap.wps.com/l/cbCailXiANh5tld1","pdf",120208,1,2,"English","en",105,"# Hypothesis / aims of study\n# Study design, materials and methods\n# Results\n# Interpretation of results\n# Concluding Message","[{\"question\":\"Which measures differed most between OAB with detrusor overactivity and without detrusor overactivity?\",\"answer\":\"In the group without detrusor overactivity, sensory filling cystometry measures were higher, and maximum detrusor and vesical pressures were also higher. OAB-V8 showed the strongest relationship to urodynamic measures related to detrusor overactivity.\"}]","Urodynamic and Clinical Perspectives of Overactive Bladder in Women - Prospective Diagnostic Algorithm and Symptom/Urodynamic Evaluation | PDF",1788753899,5,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":78,"head_meta":80,"extra_data":82,"updated_unix":28},"urodynamic-and-clinical-perspectives-of-overactive-bladder-in-women-prospective-diagnostic-algorithm-and-symptomurodynamic-evaluation","",{"@graph":36,"@context":77},[37,53,68],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,47,50],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":21},"https://docshare.wps.com/document/","Document",{"item":48,"name":12,"@type":43,"position":49},"https://docshare.wps.com/document/healthcare/",3,{"item":51,"name":13,"@type":43,"position":52},"https://docshare.wps.com/document/urodynamic-and-clinical-perspectives-of-overactive-bladder-in-women-prospective-diagnostic-algorithm-and-symptomurodynamic-evaluation/213122/",4,{"url":51,"name":13,"@type":54,"author":55,"headline":13,"publisher":57,"fileFormat":60,"inLanguage":23,"description":14,"dateModified":61,"datePublished":62,"encodingFormat":60,"isAccessibleForFree":63,"interactionStatistic":64},"DigitalDocument",{"name":9,"@type":56},"Person",{"url":41,"name":58,"@type":59},"DocShare","Organization","application/pdf","2026-09-11","2026-09-07",true,{"@type":65,"interactionType":66,"userInteractionCount":20},"InteractionCounter",{"@type":67},"ViewAction",{"@type":69,"mainEntity":70},"FAQPage",[71],{"name":72,"@type":73,"acceptedAnswer":74},"Which measures differed most between OAB with detrusor overactivity and without detrusor overactivity?","Question",{"text":75,"@type":76},"In the group without detrusor overactivity, sensory filling cystometry measures were higher, and maximum detrusor and vesical pressures were also higher. OAB-V8 showed the strongest relationship to urodynamic measures related to detrusor overactivity.","Answer","https://schema.org",{"og:url":51,"og:type":79,"og:title":13,"og:site_name":58,"og:description":14},"article",{"robots":81,"canonical":51},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":84},[85,89,93,97,101,106,109,114,119,122,126],{"id":20,"doc_module":4,"doc_module_name":46,"category_name":86,"show_sort_weight":87,"slug":88},"Story & Novel",90,"story-novel",{"id":21,"doc_module":4,"doc_module_name":46,"category_name":90,"show_sort_weight":91,"slug":92},"Literature",80,"literature",{"id":52,"doc_module":4,"doc_module_name":46,"category_name":94,"show_sort_weight":95,"slug":96},"Exam",70,"exam",{"id":29,"doc_module":4,"doc_module_name":46,"category_name":98,"show_sort_weight":99,"slug":100},"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":46,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":46,"category_name":12,"show_sort_weight":107,"slug":108},40,"healthcare",{"id":110,"doc_module":4,"doc_module_name":46,"category_name":111,"show_sort_weight":112,"slug":113},8,"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":46,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":46,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":46,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":46,"category_name":128,"show_sort_weight":29,"slug":129},19,"General","general"]