[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-detail-332137-en":59,"doc-seo-332137-105":80},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":5,"data":60},{"doc_id":61,"user_id":62,"nickname":63,"user_avatar":64,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":66,"doc_content":67,"file_id":68,"file_url":69,"file_type":70,"file_size":71,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":72,"language_code":73,"site_id":74,"html_lang":73,"table_of_contents":75,"faqs":76,"seo_title":77,"seo_description":66,"update_tm":78,"read_time":79,"preview_page_count":4},332137,137441390410,"Hazel","https://ap-avatar.wpscdn.com/avatar/2000252f4ab5702993?_k=1776741390130283984","Unveiling the Future of Oncology and Precision Medicine through Data Science","Editorial exploring how data science is reshaping oncology and precision medicine. It explains how multi-omics information from NGS—covering DNA, RNA, proteins, and epigenetic changes—supports matching patients to molecularly targeted therapies. The piece frames this progress through a Special Issue on Data Science in Cancer Genomics and Precision Medicine, highlighting seven studies that reveal actionable mutations, guide precision oncology workflows, and point to required infrastructure, data analysis scale, and clinical readiness for real-world personalized cancer care.","Editorial  \nUnveiling the Future of Oncology and Precision Medicine through Data Science  \nApostolos Zaravinos 1,2  \nCitation: Zaravinos, A. Unveiling the Future of Oncology and Precision Medicine through Data Science. Int. J. Mol. Sci. 2024, 25, 5797. [https://](https://)[ ](https://)[doi.org/10.3390/ijms25115797](doi.org/10.3390/ijms25115797)  \nReceived: 6 April 2024  \nAccepted: 22 May 2024  \nPublished: 26 May 2024  \nCopyright: © 2024 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Department of Life Sciences, School of Sciences, European University Cyprus, 2404 Nicosia, Cyprus; [a.zaravinos@euc.ac.cy](a.zaravinos@euc.ac.cy)  \n2 Cancer Genetics, Genomics and Systems Biology Laboratory, Basic and Translational Cancer Research Center (BTCRC), 1516 Nicosia, Cyprus  \nInformation generated via next-generation sequencing (NGS) technologies is often termed multi-omics data. This includes information on DNA, RNA, protein, and epigenetic modifications, among others. Using data science in cancer genomics provides a better understanding of the molecular basis of different cancers, enabling the exploitation of this information to match each patient with the most appropriate molecularly targeted therapy, widely known as “precision medicine” [1,2] . While traditional chemotherapy and radiation treatments target cellular processes common to both healthy and cancerous cells, precision medicine directs newly developed treatments, specifically to cancer cells, based on their underlying molecular profile.  \nThe field of oncology and precision medicine is rapidly evolving, fueled by the development of new laboratory and computational technologies for interrogating the molecular and cellular traits of cancer. In this setting, the integration of data science has become a cornerstone for advancing our understanding and treatment of cancer [3] . This Special Issue, entitled “Data Science in Cancer Genomics and Precision Medicine”, presents a collection of seven cutting-edge studies that characterize the synergy between data science and oncological research. These contributions not only showcase new findings, but also indicate the path toward personalized cancer care, underscoring the essential role of big data, genomic analysis, and computational biology in transforming patient outcomes.  \nThe first publication of this Issue, submitted by Kraus et al., presents an unprecedented examination of how precision medicine can be used to more effectively combat HPV-related gynecological malignancies. In cervical cancer treatments, several targeted approaches have been used over the past years, including the anti-VEGF inhibitor (bevacizumab) [4], anti-PD-1 checkpoint inhibitor (pembrolizumab) [5], or an antibody–drug conjugate that targets tissue factors (tisotumab–vedotin (TV-1) [6]) . By conducting a comprehensive retrospective analysis of patients’ molecular profiles at a tertiary cancer center, the authors delve into the practical application of precision oncology, revealing both its enormous potential and the significant challenges it faces in real-world settings. The discovery of a significant number of actionable mutations in the patient cohort highlights the promise of tailored treatments, implying a future in which therapy is tailored to the genetic makeup of an individual’s cancer, potentially improving outcomes and reducing side effects. In addition, the study provides a thorough overview of the cases handled by the interdisciplinary Molecular Tumor Board, demonstrating the complex decision-making processes involved and the factors that can cause deviations from recommended precision oncology pathways. Furthermore, this study sheds light on the broader impl","cbCaifxnB28fCZnW","https://ap.wps.com/l/cbCaifxnB28fCZnW","pdf",180711,"English","en",105,"# Editorial\n## Multi-omics and precision medicine\n## Special Issue overview\n## Precision oncology in real-world settings","[{\"question\":\"How does data science contribute to precision medicine in oncology?\",\"answer\":\"By analyzing multi-omics data from technologies such as NGS, it helps reveal the molecular basis of cancers and supports matching patients to molecularly targeted therapies.\"},{\"question\":\"What is the focus of the Special Issue mentioned in the editorial?\",\"answer\":\"The Special Issue, “Data Science in Cancer Genomics and Precision Medicine,” presents seven cutting-edge studies on the synergy between data science and cancer research, emphasizing personalized cancer care.\"},{\"question\":\"What challenges does the editorial highlight for implementing precision oncology?\",\"answer\":\"It notes systemic and infrastructural changes needed for real-world adoption, such as improving access to targeted treatments and ensuring healthcare professionals can interpret complex genomic data.\"}]","Unveiling the Future of Oncology and Precision Medicine through Data Science | PDF",1789996967,13,{"code":4,"msg":81,"data":82},"ok",{"site_id":74,"language":73,"slug":83,"title":65,"keywords":84,"description":66,"schema_data":85,"social_meta":139,"head_meta":141,"extra_data":143,"updated_unix":144},"unveiling-the-future-of-oncology-and-precision-medicine-through-data-science","",{"@graph":86,"@context":138},[87,101,121],{"@type":88,"itemListElement":89},"BreadcrumbList",[90,94,96,99],{"item":91,"name":92,"@type":93,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":95,"name":9,"@type":93,"position":14},"https://docshare.wps.com/document/",{"item":97,"name":40,"@type":93,"position":98},"https://docshare.wps.com/document/research-report/",3,{"item":100,"name":65,"@type":93,"position":19},"https://docshare.wps.com/document/unveiling-the-future-of-oncology-and-precision-medicine-through-data-science/332137/",{"url":100,"name":65,"@type":102,"image":103,"author":108,"headline":65,"publisher":110,"fileFormat":113,"inLanguage":73,"description":66,"dateModified":114,"datePublished":115,"encodingFormat":113,"isAccessibleForFree":116,"interactionStatistic":117},"DigitalDocument",{"url":104,"@type":105,"width":106,"height":107},"https://docshare.wps.com/thumbnails/unveiling-the-future-of-oncology-and-precision-medicine-through-data-science/332137.png","ImageObject",300,407,{"name":63,"@type":109},"Person",{"url":91,"name":111,"@type":112},"DocShare","Organization","application/pdf","2026-10-30","2026-09-21",true,{"@type":118,"interactionType":119,"userInteractionCount":39},"InteractionCounter",{"@type":120},"ViewAction",{"@type":122,"mainEntity":123},"FAQPage",[124,130,134],{"name":125,"@type":126,"acceptedAnswer":127},"How does data science contribute to precision medicine in oncology?","Question",{"text":128,"@type":129},"By analyzing multi-omics data from technologies such as NGS, it helps reveal the molecular basis of cancers and supports matching patients to molecularly targeted therapies.","Answer",{"name":131,"@type":126,"acceptedAnswer":132},"What is the focus of the Special Issue mentioned in the editorial?",{"text":133,"@type":129},"The Special Issue, “Data Science in Cancer Genomics and Precision Medicine,” presents seven cutting-edge studies on the synergy between data science and cancer research, emphasizing personalized cancer care.",{"name":135,"@type":126,"acceptedAnswer":136},"What challenges does the editorial highlight for implementing precision oncology?",{"text":137,"@type":129},"It notes systemic and infrastructural changes needed for real-world adoption, such as improving access to targeted treatments and ensuring healthcare professionals can interpret complex genomic data.","https://schema.org",{"og:url":100,"og:type":140,"og:title":65,"og:site_name":111,"og:description":66},"article",{"robots":142,"canonical":100},"index,follow",{"doc_id":61,"site_id":74},1790189212]