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neurostructural subtypes: results of machine learning on brain images from 4,291 individuals with schizophrenia  \nPermalink  \n[https://escholarship.org/uc/item/049230gd](https://escholarship.org/uc/item/049230gd)  \nJournal  \nmedRxiv, 4(10-23)  \nAuthors  \nJiang, Yuchao  \nLuo, Cheng Wang, Jijunet al.  \nPublication Date  \n2023-10-12  \nDOI  \n10.1101/2023.10.11.23296862  \nCopyright Information  \nThis work is made available under the terms of a Creative Commons AttributionNonCommercial-NoDerivatives License, available at [https://creativecommons.org/licenses/by-nc-nd/4.0/](https://creativecommons.org/licenses/by-nc-nd/4.0/)  \nPeer reviewed  \n[eScholarship.org](eScholarship.org) Powered by the California Digital Library  \nUniversity of California  \nmedRxiv preprint doi: [https://doi.org/10.1101/2023.10.11.23296862](https://doi.org/10.1101/2023.10.11.23296862); this version posted October 12, 2023. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.  \nIt is made available under a CC-BY-NC-ND 4.0 International license .  \n1 Two neurostructural subtypes: results of machine learning on brain  \n2 images from 4,291 individuals with schizophrenia  \n3  \n4 Yuchao Jiang1,2 , Cheng Luo3,4,5, Jijun Wang6 , Lena Palaniyappan7 , Xiao Chang1,2 , Shitong Xiang1,2 , Jie  \n5 Zhang1,2 , Mingjun Duan3 , Huan Huang3 , Christian Gaser8,9,10 , Kiyotaka Nemoto11 , Kenichiro Miura12 ,  \n6 Ryota Hashimoto12 , Lars T. Westlye13,14,15 , Genevieve Richard13,14,15 , Sara Fernandez-Cabello13,14,15 ,  \n7 Nadine Parker14 , Ole A. Andreassen14 , Tilo Kircher16 , Igor Nenadić16 , Frederike Stein16 , Florian Thomas-  \n8 Odenthal16 , Lea Teutenberg16 , Paula Usemann16 , Udo Dannlowski17 , Tim Hahn17 , Dominik Grotegerd17 ,  \n9 Susanne Meinert17 , Rebekka Lencer17,68,69, Yingying Tang6, Tianhong Zhang6 , Chunbo Li6 , Weihua  \n10 Yue18,19,20, Yuyanan Zhang18 , Xin Yu18 , Enpeng Zhou18 , Ching-Po Lin21 , Shih-Jen Tsai22 , Amanda L.  \n11 Rodrigue23 , David Glahn23 , Godfrey Pearlson24 , John Blangero25 , Andriana Karuk26,27 , Edith Pomarol-  \n12 Clotet26,27 , Raymond Salvador26,27 , Paola Fuentes-Claramonte26,27 , María Ángeles Garcia-León26,27 ,  \n13 Gianfranco Spalletta28 , Fabrizio Piras28 , Daniela Vecchio28 , Nerisa Banaj28, Jingliang Cheng29 , Zhening  \n14 Liu30 , Jie Yang30 , Ali Saffet Gonul31 , Ozgul Uslu32 , Birce Begum Burhanoglu32 , Aslihan Uyar Demir31 ,  \n15 Kelly Rootes-Murdy33 , Vince D. Calhoun33 , Kang Sim34,35,36 , Melissa Green37 , Yann Quidé38, Young Chul  \n16 Chung39,40,41 , Woo-Sung Kim39,41 , Scott R. Sponheim42,43,44 , Caroline Demro43 , Ian S. Ramsay43 , Felice  \n17 Iasevoli45 , Andrea de Bartolomeis45 , Annarita Barone45 , Mariateresa Ciccarelli45 , Arturo Brunetti46 , Sirio  \n18 Cocozza46 , Giuseppe Pontillo46 , Mario Tranfa46 , Min Tae M. Park47,48 , Matthias Kirschner49,50 , Foivos  \n19 Georgiadis50 , Stefan Kaiser49 , Tamsyn E Van Rheenen51,52 , Susan L Rossell52 , Matthew Hughes52 ,  \n20 William Woods52 , Sean P Carruthers52 , Philip Sumner52 , Elysha Ringin53 , Filip Spaniel53 , Antonin  \n21 Skoch53,54 , David Tomecek53,55,56 , Philipp Homan57,58 , Stephanie Homan59,60 , Wolfgang Omlor57 ,  \n22 Giacomo Cecere57 , Dana D Nguyen61 , Adrian Preda62 , Sophia Thomopoulos63 , Neda Jahanshad63 ,  \n23 Long-Biao Cui64 , Dezhong Yao3,4,5 , Paul M. Thompson63 , Jessica A. Turner65 , Theo G. M. van Erp66,67 ,  \n24 Wei Cheng1,2,70,71,72 , ENIGMA Schizophrenia Consortium, ZIB Consortium, Jianfeng Feng1,2,72,73,74,75,76,* 25  \n26 1 Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, China.  \n27 2 Key Laboratory of Computational Neuroscience and Brain Inspired Intelligence (Fudan University),  \n28 Ministry of Education, Shanghai, China.  \n29 3 The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformati","cbCailrWIldhXV9G","https://ap.wps.com/l/cbCailrWIldhXV9G","pdf",2954571,"English","# Title and publication information\n## Study title\n## Authors and affiliations\n## Licensing and preprint notice","[{\"question\":\"What is the document’s main research topic?\",\"answer\":\"It reports two neurostructural subtypes derived from machine learning applied to brain images in schizophrenia.\"},{\"question\":\"How many individuals are included in the machine learning analysis?\",\"answer\":\"The document specifies results based on 4,291 individuals with schizophrenia.\"},{\"question\":\"What publication platform and licensing are associated with this work?\",\"answer\":\"The document is a medRxiv preprint and is released under a CC-BY-NC-ND 4.0 International license, with a note that it is not certified by peer review.\"}]","Two neurostructural subtypes - results of machine learning on brain images from schizophrenia - 4291 individuals | PDF",1785895601,101]