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It describes DNA and chromatin in interphase, chromosome formation during prophase, spindle fiber alignment in metaphase, sister chromatid separation in anaphase, and nuclear re-formation as cells complete telophase. The packet links these stages to New York State Living Environment standards and guides students through a hands-on twizzler and licorice simulation, followed by vocabulary and review questions.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/twizzler-mitosis-the-mitosis-process-activity/414427/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/twizzler-mitosis-the-mitosis-process-activity/414427.png","ImageObject",300,407,{"name":92,"@type":93},"Quinn Holloway","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is interphase and what happens to DNA before mitosis begins?","Question",{"text":112,"@type":113},"Interphase is when the cell grows and makes an exact duplication of its DNA before mitosis starts.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What key event distinguishes anaphase from metaphase?",{"text":117,"@type":113},"In metaphase, spindle fibers form and help separate sister chromatids, while in anaphase spindle fibers pull sister chromatids apart and move them to opposite sides of the cell.",{"name":119,"@type":110,"acceptedAnswer":120},"How does telophase complete cell division?",{"text":121,"@type":113},"During telophase, chromosomes reach the sides of the cell and each set forms around a new nucleus, creating two new daughter cells.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},414427,1790883054,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},2336474466712,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Twizzler Mitosis  \nBy: Joyce Green  \nThe Mitosis Process  \nA cell follows the same general pattern of birth, growth, and aging as an entire organism. The body maintains healthy tissue by constantly replacing dying cells with new ones.  \nThe genetic information of the cell necessary to make new proteins, structures and eventually new cells is contained (encoded) in molecules of DNA. Each molecule of DNA must be duplicated before the cell divides, so that there will be equal amounts to pass on to each of the two daughter cells.  \nDuring most of a cell’s life, DNA attached to protein is contained in long thread-like material in the nucleus called chromatin. These strands are too small to be seen by most microscopes. During cell division however the DNA condenses into chromosomes which can be seen.  \nThere are five main stages to a cell lifecycle. Most of the time, a cell is in the stage called Interphase, where the cell can grow and copy its DNA. This occurs prior to mitosis.  \nInterphase-During this stage, prior to the start of mitosis, the DNA in the cell, called the parent cell, makes an exact duplication of itself.  \nOnce the DNA is duplicated, the cell can go through a process called  \nProphase-During this stage, the cell prepares to divide by dissolving the membrane around the nucleus and the chromatin condenses into  \nchromosomes.  \nMetaphase-During this stage, spindle fibers form along the sides of the cell. Spindle fibers help separate the sister chromatids.  \nAnaphase-During this stage the spindle fibers pull the sister chromatids apart and towards the side of the cell.  \nTelophase-During this stage, the chromosomes reach the sides of the cell and cell begins to divide. The membrane of a nucleus forms around each set of chromosomes, creating a new nucleus for each daughter cell.  \nVOCABULARY  \nAnaphase  \nChromatin  \nChromosomes  \nDaughter Cell Interphase  \nMetaphase Mitosis Parent Cell  \nProphase  \nSister Chromatids  \nSpindle Fibers  \nTelophase  \n\n| Inside This Packet |  |\n| --- | --- |\n| The Mitotis Process | 1 |\n| New York State Standards | 1 |\n| Activity: Twizzler Mitosis | 2 |\n| Review Questions | 3 |\n| Parent Cell Handout | 4 |\n| Daughter Cells Handout | 5 |\n\nmitosis. This is the way a cell sorts and divides its genetic information in the nucleus.  \nThe four stages of mitosis are prophase, metaphase, anaphase, and telophase.  \nNew York State Standards  \nHigh School Living Science  \nStandard 4:  \nKey Idea 2.1d, 2.1f, 2.1g, 2.1h, 2.1k  \nKey Idea 2.2d, 2.2e  \nKey Idea 3.1d  \nLife Sciences-Prior Module 5 High School Page 1  \nActivity: Twizzler Mitosis  \nMATERIALS NEEDED  \nShoelace licorice Marshmallows  \nParent and daughter cell handouts  \nStudents should be able to:  \nDescribe how cells sort out the genetic material of the cell during the process of mitosis.  \nList the phases of mitosis.  \nDescribe what happens in each phase of mitosis.  \nDraw what occurs in each phase of mitosis.  \nWhat to do:  \nUsing your materials, you will recreate the process of mitosis by simulating the different phases you just read about.  \nInterphase  \nLay your cell handouts on your table. Start off in the Parent Cell with one long and one short red twizzler. Replicate each chromosome by laying the other red chromosomes next to the original chromosomes.  \nTake a marshmallow and cut a hole in the center, then slide the two copies of DNA through the marshmallow. The two copies of DNA are called sister chromatids and are being held together by a centromere, a section of DNA. Repeat this for the other copy of DNA.  \nProphase  \nMove your sister chromatids around the cell in preparation for cell division.  \nMetaphase  \nTake two strands of shoestring licorice and lay them down on opposite sides of the cell. Next, line up the sister chromatids end to end in the middle of the cell. Then, have one spindle fiber connect to each sister chromatid.  \nAnaphase  \nRemove the marshmallow from your twizzlers and separate the sister chromatids so that one goes t","cbCaimhGCKpj6LJJ","https://ap.wps.com/l/cbCaimhGCKpj6LJJ","pdf",189545,"English","# The Mitosis Process\n## DNA, chromatin, and chromosomes\n## Five stages of mitosis: Interphase to Telophase\n# Activity: Twizzler Mitosis\n## Materials needed and setup\n## Interphase\n## Prophase\n## Metaphase\n## Anaphase\n## Telophase\n# Review Questions\n# Vocabulary","[{\"question\":\"What is interphase and what happens to DNA before mitosis begins?\",\"answer\":\"Interphase is when the cell grows and makes an exact duplication of its DNA before mitosis starts.\"},{\"question\":\"What key event distinguishes anaphase from metaphase?\",\"answer\":\"In metaphase, spindle fibers form and help separate sister chromatids, while in anaphase spindle fibers pull sister chromatids apart and move them to opposite sides of the cell.\"},{\"question\":\"How does telophase complete cell division?\",\"answer\":\"During telophase, chromosomes reach the sides of the cell and each set forms around a new nucleus, creating two new daughter cells.\"}]","Twizzler Mitosis - The Mitosis Process - Activity | PDF",1790597510,13]