[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-457520-105":59,"doc-detail-457520-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","treatment-of-bronchobiliary-fistula-a-13-year-experience","Treatment of bronchobiliary fistula: a 13-year experience","","Bronchobiliary fistula (BBF) is a rare but fatal condition with limited case reporting and no unified treatment consensus. A retrospective review analyzed 17 BBF patients diagnosed from January 1, 2012 to May 30, 2025, evaluating presenting symptoms, diagnostic strategies, treatment approaches, and outcomes. All patients reported cough and characteristic biliptysis, with imaging and cholangiography supporting bronchobiliary communication. Surgical treatment occurred in selected cases, while minimally invasive methods provided effective symptomatic palliation in malignant disease. Prognosis remained poor overall. Multidisciplinary individualized management is essential for optimizing outcomes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/treatment-of-bronchobiliary-fistula-a-13-year-experience/457520/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/treatment-of-bronchobiliary-fistula-a-13-year-experience/457520.png","ImageObject",300,407,{"name":92,"@type":93},"Aldword","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What clinical features are characteristic of bronchobiliary fistula in this study?","Question",{"text":112,"@type":113},"All 17 patients had cough and characteristic biliptysis. The paper describes classic manifestations including refractory cough with bilioptysis, recurrent pulmonary infections, jaundice, and chest/abdominal pain.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was BBF diagnosed in the reported cases?",{"text":117,"@type":113},"The study used symptom evaluation plus diagnostic confirmation through sputum/bile component analysis, fiberoptic bronchoscopy, and imaging such as CT/MRI/MRCP and cholangiography to demonstrate communication between the biliary tree and bronchial system.",{"name":119,"@type":110,"acceptedAnswer":120},"What treatment approaches were used and how did they relate to outcomes?",{"text":121,"@type":113},"Surgery was performed in a subset of patients, with some achieving long-term survival, while minimally invasive interventions provided effective symptomatic palliation in most patients, especially in malignant cases. The study also highlights that uncontrolled BBF and complications contributed to deaths in some cases.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},457520,1791131902,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},2336478940917,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Yu etal. BMC Surgery (2026) 26:21  \n[https://doi.org/10.1186/s12893-025-03366-x](https://doi.org/10.1186/s12893-025-03366-x)  \nBMC Surgery  \nRESEARCH Open Access  \nTreatment of bronchobiliary fistula: a 13-year  experience  \nXi Yu 1†, Yuan Ding 1†, Yi Zhang2†, Bin Chen 1, Yun-Peng Hua 1, Shao-Qiang Li 1, Zi-Hao Dai 1*, Jun-Feng Liu3* and Shun-Li Shen 1*  \nAbstract  \nBackground Bronchobiliary fistula (BBF) is a rare but fatal disease. Due to its rarity, only a limited number of cases have been reported, leading to a lack of consensus on appropriate treatment strategies.  \nMethods We conducted a retrospective analysis of clinical data of 17 patients diagnosed with BBF between January 1, 2012, and May 30, 2025, focusing on the the presenting symptoms, diagnostic approaches, treatment modalities, and outcomes.  \nResults All 17 patients had cough and pathognomonic biliptysis. Sputum analysis confirmed bile components in all samples from 3 patients, and fiber bronchoscopy revealed yellow-green bilious sputum in 6 patients. Computed tomography (CT) or magnetic resonance imaging (MRI) demonstrated communication between the bile duct and the bronchial tree in 9 patients. Cholangiography showed contrast medium passing through a fistulous tract into the bronchi in 10 patients. Surgical intervention was performed in 6 patients, 3 of whom achieved long-term survival (> 24 months) . Minimally invasive interventions provided effective symptomatic palliation in 10 of 11 patients. Among these 10 patients, 3 achieved long-term survival (> 24 months), with an additional 3 remaining alive and under ongoing follow-up (though not yet reaching the 24-month threshold) . Of the 8 fatalities, 2 were directly attributed to uncontrolled BBF and its complications (sepsis or hepatic failure) . The remaining deaths resulted from progressive malignancy (n = 3), postoperative complications (pneumothorax/respiratory failure, n = 1; hemorrhagic shock/ disseminated intravascular coagulation, n = 1), and post-transplant septic shock (n = 1) .  \nConclusions BBF is associated with poor prognosis. Minimally invasive therapies offer effective palliation in malignant cases, whereas surgical intervention may provide curative potential in selected benign cases.  \nIndividualized, multidisciplinary management is essential for optimizing outcomes.  \nKeywords Bronchobiliary fistulas (BBF), Diagnosis, Surgery, Minimally invasive treatment, Prognosis  \n†Xi Yu, Yuan Ding andYi Zhang contributed equally to this work.  \n*Correspondence:  \nZi-Hao Dai [daizihao@mail2.sysu.edu.cn](daizihao@mail2.sysu.edu.cn)[ ](daizihao@mail2.sysu.edu.cn)Jun-Feng Liu [liujunf2@mail.sysu.edu.cn](liujunf2@mail.sysu.edu.cn)[ ](liujunf2@mail.sysu.edu.cn)Shun-Li Shen [shenshli@mail.sysu.edu.cn](shenshli@mail.sysu.edu.cn)  \n1Department of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of SunYat-sen University, No. 58, Zhong Shan Road 2, Guangzhou 510060, Guangdong, China  \n2Department of Hepatobiliary surgery, the Third Affiliated Hospital, Sun Yat-sen University, No. 600 Tian he Road, Guangzhou 510630, China 3Department of Medical Records, the First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhong Shan Road 2, Guangzhou 510060, Guangdong, China  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not i","cbCaispocaBjteLT","https://ap.wps.com/l/cbCaispocaBjteLT","pdf",1672649,"English","# Abstract\n# Introduction\n## Background and clinical classification\n## Etiology of acquired BBF\n## Classical manifestations and diagnostic pitfalls\n## Diagnostic methods and imaging roles\n## Historical context","[{\"question\":\"What clinical features are characteristic of bronchobiliary fistula in this study?\",\"answer\":\"All 17 patients had cough and characteristic biliptysis. The paper describes classic manifestations including refractory cough with bilioptysis, recurrent pulmonary infections, jaundice, and chest/abdominal pain.\"},{\"question\":\"How was BBF diagnosed in the reported cases?\",\"answer\":\"The study used symptom evaluation plus diagnostic confirmation through sputum/bile component analysis, fiberoptic bronchoscopy, and imaging such as CT/MRI/MRCP and cholangiography to demonstrate communication between the biliary tree and bronchial system.\"},{\"question\":\"What treatment approaches were used and how did they relate to outcomes?\",\"answer\":\"Surgery was performed in a subset of patients, with some achieving long-term survival, while minimally invasive interventions provided effective symptomatic palliation in most patients, especially in malignant cases. The study also highlights that uncontrolled BBF and complications contributed to deaths in some cases.\"}]","Treatment of bronchobiliary fistula: a 13-year experience | PDF",1790749594,25]