[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-416282-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-416282-en":131},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","transvaginal-ultrasound-for-detecting-parametrial-involvement-in-suspected-deep-pelvic-endometriosis-updated-meta-analysis","Transvaginal ultrasound for detecting parametrial involvement in suspected deep pelvic endometriosis - updated meta-analysis","","Updated meta-analysis evaluates the diagnostic accuracy of transvaginal ultrasound (TVS) for detecting lateral parametrial involvement in women with suspected deep pelvic endometriosis, using laparoscopy with or without histology as the reference standard. Searches in Web of Science, PubMed, and Scopus from January 2021 to May 2024 were combined with prior meta-analysis data. Eight studies (6728 women; 13,456 parametria) were included; pooled sensitivity was 63% and specificity 98%. Laterality-specific analyses showed sensitivity ~84–85% with specificity ~97–98%, with high heterogeneity and improved overall performance.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/transvaginal-ultrasound-for-detecting-parametrial-involvement-in-suspected-deep-pelvic-endometriosis-updated-meta-analysis/416282/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/transvaginal-ultrasound-for-detecting-parametrial-involvement-in-suspected-deep-pelvic-endometriosis-updated-meta-analysis/416282.png","ImageObject",300,407,{"name":42,"@type":43},"Dipper","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-03","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",11,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What clinical question does this updated meta-analysis address?","Question",{"text":63,"@type":64},"It evaluates how accurately transvaginal ultrasound (TVS) detects lateral parametrial involvement in women with suspected deep pelvic endometriosis, using laparoscopy with or without histology as the reference standard.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What data and time range were used in the study selection?",{"text":68,"@type":64},"The authors searched Web of Science, PubMed, and Scopus from January 2021 to May 2024 for TVS studies assessing parametrial involvement, then combined the extracted data with their previous meta-analysis results.",{"name":70,"@type":61,"acceptedAnswer":71},"What were the pooled sensitivity and specificity results for TVS?",{"text":72,"@type":64},"Overall pooled sensitivity was 63% (95% CI 31–86%) and pooled specificity was 98% (95% CI 96–99%). Laterality analyses showed sensitivity around 84–85% with specificity around 97–98% for left and right parametrium.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},416282,1790977212,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,127],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":116,"doc_module":4,"doc_module_name":25,"category_name":117,"show_sort_weight":118,"slug":119},9,"Religion & Spirituality",20,"religion-spirituality",{"id":118,"doc_module":4,"doc_module_name":25,"category_name":121,"show_sort_weight":118,"slug":122},"World Cup","world-cup",{"id":124,"doc_module":4,"doc_module_name":25,"category_name":125,"show_sort_weight":124,"slug":126},10,"Lifestyle","lifestyle",{"id":128,"doc_module":4,"doc_module_name":25,"category_name":129,"show_sort_weight":97,"slug":130},19,"General","general",{"code":4,"msg":82,"data":132},{"doc_id":79,"user_id":133,"nickname":42,"user_avatar":134,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":111,"language":140,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":12,"update_tm":144,"read_time":118,"preview_page_count":4},1374404997633,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Ultrasound Obstet Gynecol 2026; 67: 7–14  \nPublished online 23 August 2025 in Wiley Online Library ([wileyonlinelibrary.com](wileyonlinelibrary.com)). DOI: 10.1002/uog.70004.  \nThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.  \nTransvaginal ultrasound for detecting parametrial involvement in suspected deep pelvic endometriosis:  \nupdated meta-analysis  \nJ. L. ALC´AZAR1, C. MONTOYA2 , C. CANDAU3 , C. CATALAN4 , R. OROZCO1 , M. ´A . PASCUAL5, S. AJOSSA6 and S. GUERRIERO6  \n1 Department of Obstetrics and Gynecology, Hospital Quironsalud, M laga, Spain; 2 Department Gynecology, Cl nica El Rosario, Medelln, Colombia; 3 Department of Obstetrics and Gynecology, Hospital Puerta del Mar, C diz, Spain; 4 Department of Gynecology, Faculty of Medicine, Pontificia Universidad Cat lica de Chile, Santiago, Chile; 5 Department of Obstetrics, Gynecology and Reproduction, Hospital Universitari Dexeus, Barcelona, Spain; 6 Centro Integrato di Procreazione Medicalmente Assistita (PMA) e Diagnostica  \nOstetrico-Ginecologica, Policlinico Universitario Duilio Casula, University of Cagliari, Cagliari, Italy  \nKEYWORDS: endometriosis; parametrium; transvaginal; ultrasound  \n\n| ABSTRACT\u003Cbr>Objective To perform an updated meta-analysis evaluating the diagnostic performance of transvaginal ultrasound (TVS) for detecting lateral parametrial involvement in women with suspected deep pelvic endometriosis.\u003Cbr>Methods A literature search was performed in the Web of Science, PubMed and Scopus databases from January 2021 to May 2024 for studies evaluating TVS for detecting parametrial involvement in women with suspected deep pelvic endometriosis, using laparoscopy with or without histology as the reference standard. The information gathered was combined with data from our previous meta-analysis on this topic. Pooled sensitivity and specificity were calculated overall and for subgroup analyses considering parametrial laterality. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to evaluate study quality.\u003Cbr>Results After exclusions, four new studies fulfilling the selection criteria were identified. Combined with the four studies included in our previous meta-analysis, eight studies including a total of 6728 women (13 456 parametria) were included. The mean prevalence of parametrial involvement was 21.3% . The pooled sensitivity and specificity of TVS for detecting parametrial involvement were 63%(95% CI, 31–86%) and 98%(95% CI, 96–99%), respectively. When considering only the five studies that reported laterality, the corresponding values were 85%(95% CI, 64–95%) and 98% (95% CI, 92–99%) for the left parametrium and 84%(95% CI, 61 –94%) and | 97%(95% CI, 92–99%) for the right parametrium. Heterogeneity was high for the overall analysis and subgroup analyses.\u003Cbr>Conclusions The diagnostic performance of TVS for detecting parametrial involvement in women with suspected deep pelvic endometriosis is better than that reported previously. This may be attributable to the use of a standardized TVS scanning technique and improved knowledge of pelvic ultrasound anatomy. Accurate parametrial assessment could improve surgical planning and patient outcome. © 2025 The Author(s) . Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.\u003Cbr>INTRODUCTION\u003Cbr>Endometriosis is a relatively common benign chronic disease affecting mainly women of reproductive age1. Transvaginal ultrasound (TVS) is considered the first-line imaging technique for diagnosing this disease2. Several meta-analyses have shown that TVS has good diagnostic performance for endometriosis, similar to that of magnetic resonance imaging (MRI)3–6. In 2016, the Internatio","cbCaia1iTu7tzoF4","https://ap.wps.com/l/cbCaia1iTu7tzoF4","pdf",483605,"English","# Objective\n# Methods\n## Literature search and reference standard\n## Statistical synthesis and subgroup analyses\n## Study quality assessment\n# Results\n## Study selection and population\n## Pooled diagnostic accuracy\n## Laterality findings and heterogeneity\n# Conclusions\n# Background (Introduction)","[{\"question\":\"What clinical question does this updated meta-analysis address?\",\"answer\":\"It evaluates how accurately transvaginal ultrasound (TVS) detects lateral parametrial involvement in women with suspected deep pelvic endometriosis, using laparoscopy with or without histology as the reference standard.\"},{\"question\":\"What data and time range were used in the study selection?\",\"answer\":\"The authors searched Web of Science, PubMed, and Scopus from January 2021 to May 2024 for TVS studies assessing parametrial involvement, then combined the extracted data with their previous meta-analysis results.\"},{\"question\":\"What were the pooled sensitivity and specificity results for TVS?\",\"answer\":\"Overall pooled sensitivity was 63% (95% CI 31–86%) and pooled specificity was 98% (95% CI 96–99%). Laterality analyses showed sensitivity around 84–85% with specificity around 97–98% for left and right parametrium.\"}]","Transvaginal ultrasound for detecting parametrial involvement in suspected deep pelvic endometriosis - updated meta-analysis | PDF",1790604852]