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This study translates and cross-culturally adapts the Hyperacusis Screening Questionnaire into Brazilian Portuguese using forward translation, back-translation, expert committee review, and pretesting/validation. Responses from 324 WS families were analyzed.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/translation-and-cross-cultural-adaptation-of-a-questionnaire-for-assessing-hyperacusis-in-williams-syndrome/435877/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/translation-and-cross-cultural-adaptation-of-a-questionnaire-for-assessing-hyperacusis-in-williams-syndrome/435877.png","ImageObject",300,407,{"name":42,"@type":43},"Patrick","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-05","2026-09-29",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",7,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What is the main goal of translating and adapting the questionnaire?","Question",{"text":63,"@type":64},"To translate and perform the cross-cultural adaptation of the Hyperacusis Screening Questionnaire for use in Brazilian Portuguese, enabling practical clinical screening of hyperacusis in Williams syndrome.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was the questionnaire adaptation carried out?",{"text":68,"@type":64},"Two English-fluent translators produced initial translations, followed by synthesis, back-translation, expert committee review for semantic and linguistic adaptation, and pretesting plus content and appearance validation.",{"name":70,"@type":61,"acceptedAnswer":71},"What do the study results show about hyperacusis in the adapted questionnaire responses?",{"text":72,"@type":64},"The adapted version was similar to the original in general and referential meaning. Among 324 participating families, 85.2% reported hyperacusis as an ongoing symptom, supporting the instrument’s utility for screening.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},435877,1790774154,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,109,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":107,"slug":108},40,"healthcare",{"id":110,"doc_module":4,"doc_module_name":25,"category_name":111,"show_sort_weight":112,"slug":113},8,"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":55,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":102,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144,"preview_page_count":4},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","Article published online: 2025-09-08  \nOriginal Article 1  \nTranslation and cross-cultural adaptation of a questionnaire for assessing hyperacusis in Williams syndrome  \nJacqueline Aquino do Nascimento 1 Lucas Pinto Mielle 1 Liliane Aparecida Fagundes Silva 1 Alessandra Giannella Samelli 1 Carla Gentile Matas 1  \n1 Universidade de São Paulo, Faculdade de Medicina, Departamento  \nde Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brazil.  \nArq. Neuro-Psiquiatr. 2025;83(9):s00451811624 .  \nAddress for correspondence Lucas Pinto Mielle (email: [lucas.mielle@fm. usp.br](lucas.mielle@fm. usp.br))  \nAbstract  \nKeywords  \n► Williams Syndrome  \n► Hyperacusis  \n► Audiology  \n► Translating  \n► Surveys and Questionnaires  \nBackground Williams syndrome (WS) is a genetic, multisystemic, and neurodevelopmental disorder. The prevalence of auditory hypersensitivity in WS is high, especially in childhood, with reports in the literature from 94 to 100% of individuals evaluated, which can generate significant impacts on their quality of life. Therefore, the existence of instruments for screening hyperacusis that are easy and quick to apply for use in clinical routine is essential.  \nObjective To translate and perform the cross-cultural adaptation of the Hyperacusis Screening Questionnaire into Brazilian Portuguese.  \nMethods A questionnaire concerning auditory hypersensitivity in WS was translated by two translators who are fluent in English. After the synthesis of the translations, back-translation was performed to analyze similarity, a meeting of the expert committee for semantic and linguistic adaptation of the instrument was held, and pretesting and validation of content and appearance was conducted.  \nResults The translated and adapted version of the questionnaire was similar to the original regarding general and referential meaning. Answers from 324 families of individuals with WS were included, 85.2% of those reported hyperacusis as a ongoing symptom.  \nConclusion The translation and cross-cultural adaptation of the questionnaire were performed according to the methodology recommended in the literature, with necessary equivalences being made for the Brazilian reality. The instrument developed and tested in the present study proved to be useful in screening for hyperacusis in the population with WS, allowing its use in future investigations on the subject and comparison with other studies.  \nreceived  \nMarch 20, 2025  \nreceived in its final form May 22, 2025  \naccepted  \nJune 28, 2025  \nDOI [https://doi.org/](https://doi.org/)[ ](https://doi.org/)10.1055/s-0045-1811624 . ISSN 0004-282X.  \nEditor-in-Chief: Hélio A. G. Teive.  \nAssociate Editor: Aline Chacon Pereira.  \n© 2025 . The Author(s) .  \nThis is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit ([https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/))  \nThieme Revinter Publicações Ltda. , Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil  \n2 Hyperacusis in Williams syndrome Nascimento et al.  \nINTRODUCTION  \nWilliams syndrome (WS) is a genetic, multisystemic, and neurodevelopmental disorder that occurs in between 1:7,500 and 1:20,000 live births. 1,2 It is caused by a microdeletion in the chromosomal region 7q11 .23, which affects 􀀁 28 genes, and is equally prevalent among men and women, occurring in all types of populations around the world.3  \nHeart problems, such as supravalvular aortic stenosis, changes in calcium metabolism, characterized by infantile hypercalcemia, as well as connective tissue abnormalities, are some of the afflictions that make up this condition.1  \nHearing abnormalities are also among the most frequent findings, including progressive sensorineural hearing loss and high prevalence of conductive impairments. Even in indiv","cbCainGTSfQRwJQM","https://ap.wps.com/l/cbCainGTSfQRwJQM","pdf",427405,"English","# Abstract\n## Background\n## Objective\n## Methods\n## Results\n## Conclusion\n# Introduction\n## Clinical context of Williams syndrome\n## Auditory features and mechanisms\n## Rationale for the study","[{\"question\":\"What is the main goal of translating and adapting the questionnaire?\",\"answer\":\"To translate and perform the cross-cultural adaptation of the Hyperacusis Screening Questionnaire for use in Brazilian Portuguese, enabling practical clinical screening of hyperacusis in Williams syndrome.\"},{\"question\":\"How was the questionnaire adaptation carried out?\",\"answer\":\"Two English-fluent translators produced initial translations, followed by synthesis, back-translation, expert committee review for semantic and linguistic adaptation, and pretesting plus content and appearance validation.\"},{\"question\":\"What do the study results show about hyperacusis in the adapted questionnaire responses?\",\"answer\":\"The adapted version was similar to the original in general and referential meaning. Among 324 participating families, 85.2% reported hyperacusis as an ongoing symptom, supporting the instrument’s utility for screening.\"}]","Translation and cross-cultural adaptation of a questionnaire for assessing hyperacusis in Williams syndrome | PDF",1790675763,15]