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The review highlights its curative role in early-stage disease confined to the rectum (T1N0M0), emphasizing the need for regular computed tomography follow-up. Correct patient selection yields recurrence rates below 3%, and TAMIS may also function as salvage treatment for symptomatic high-risk patients unable or unfit for transabdominal resection.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/transanal-minimally-invasive-surgery-for-rectal-cancer-review-article/375890/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/transanal-minimally-invasive-surgery-for-rectal-cancer-review-article/375890.png","ImageObject",300,407,{"name":92,"@type":93},"Sophia Brooks","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What makes TAMIS an important option in rectal cancer?","Question",{"text":112,"@type":113},"TAMIS is considered standard care because it is organ preserving, helping reduce morbidity associated with more radical proctectomy-based procedures.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which patients are most suitable for curative TAMIS?",{"text":117,"@type":113},"TAMIS is indicated for early-stage rectal cancer (T1 with favorable pathology), including well/moderately differentiated adenocarcinoma, no lymphovascular invasion, and lesion size up to 3 cm.",{"name":119,"@type":110,"acceptedAnswer":120},"How is recurrence and progression monitored after TAMIS?",{"text":121,"@type":113},"Regular follow-up with computed tomography imaging is required, and if the disease is upstaged to deeper layers (e.g., T2 or more), further transabdominal resection is warranted.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},375890,1790811693,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":52},962084925636,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Article published online: 2025-01-09  \nReview Article 263  \nSurgery  \nTransanal Minimally Invasive Surgery for Rectal Cancer  \nSheikh Mohammad Taha Mustafa 1 Deepak Govil2 Vijay Arora3 V. K. Malik3 Shivendra Singh4 Avinash Saklani5 Rajesh Bhojwani6 Shyam Aggarwal7 Purvish M. Parikh8 C. Selvasekar9 Saumitra Rawat 10  \n1 Department of Colo Rectal Surgery, Sir Ganga Ram Hospital, New Delhi, India  \n2 Department of Surgical Gastroenterology, Indraprastha Apollo Hospital, New Delhi, India  \n3 Department of Laparoscopic Surgery, Sir Ganga Ram Hospital, New Delhi, India  \n4 Department of GI Oncosurgery, RGCI, New Delhi, India  \n5 Department of Colorectal Surgery, Tata Memorial Hospital, Mumbai, Maharashtra, India  \n6 Department of Surgical Gastroenterology, Santokba Durlabhji Memorial Hospital, Jaipur, Rajasthan, India  \n7 Department of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India  \nSouth Asian J Cancer 2024;13(4):263–266.  \nAddress for correspondence Sheikh Mohammad Taha Mustafa, MBBS, MS, MRCS, Department of Colo Rectal Surgery, Sir Ganga Ram Hospital, New Delhi 110060, India  \n(e-mail: [sheikhtaha23@gmail.com](sheikhtaha23@gmail.com)).  \n8 Department of Clinical Hematology, Sri Ram Cancer Center, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India  \n9 Clinical Services and Specialist Surgery, The Christie NHS Foundation Trust, Manchester, United Kingdom  \n10 Department of Surgical Gastroenterology, SGRH, New Delhi, India  \nAbstract  \nSheikh Mohammad Taha Mustafa  \nTransanal minimally invasive surgery (TAMIS) is considered a standard of care in rectal cancers. Its advantage is that it is organ preserving. Its main role is in early-stage cancers limited to the rectum (T1N0M0) . Regular follow-up with computed tomography scan imaging is required. When done correctly in the right patients, the recurrence rate of rectal cancer is less than 3% . TAMIS can also be used as a salvage operation in symptomatic high-risk patients who are unable to undergo or are unfit for transabdominal resection.  \nKeywords  \n► early stage  \n► curative treatment  \n► cure  \n► minimally invasive  \n► organ preserving  \nDOI [https://doi.org/10.1055/s-0044-1801775](https://doi.org/10.1055/s-0044-1801775) ISSN 2278-330X  \nHow to cite this article: Mustafa SMT, Govil D, Arora V, et al. Transanal Minimally Invasive Surgery for Rectal Cancer. South Asian J Cancer 2024;13(4):263–266.  \n© 2025 . MedIntel Services Pvt Ltd. All rights reserved.  \nThis is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ([https://creativecommons.org/licenses/by-nc-nd/](https://creativecommons.org/licenses/by-nc-nd/)[ ](https://creativecommons.org/licenses/by-nc-nd/)[4.0/](4.0/))  \nThieme Medical and Scientific Publishers Pvt. Ltd. , A-12, 2nd Floor, Sector 2, Noida-201301 UP, India  \n264 Transanal Minimally Invasive Surgery for Rectal Cancer Mustafa et al.  \nIntroduction  \nRectal cancer treatment has come a long way from initial days of abdominoperineal resection (APR) to low anterior resection (LAR) and ultra-low anterior resection (uLAR) and transanal total mesorectal resection (TaTME) .1 All these procedures involve proctectomy and have certain morbidity and very occasionally mortality associated with them. The change in the bowel functions and episodes of incontinence and LAR syndrome often lead to unhappy patients. There has been a shift toward organ preservation over the past many years, and the watch and wait policy is slowly becoming popular in select patients who have complete clinical response to neoadjuvant chemotherapy and radiation.  \nTransanal minimally invasive surgery (TAMIS) is an organ-preserving surgery for rectal cancer. It has both curative and diagnos","cbCaihGKhNZ5Ugy5","https://ap.wps.com/l/cbCaihGKhNZ5Ugy5","pdf",1239613,"English","# Abstract\n# Introduction\n## Organ preservation and treatment evolution\n## NCCN-indicated early-stage criteria\n## Indications, advantages, disadvantages, and complications\n# TAMIS development and comparison with TEM","[{\"question\":\"What makes TAMIS an important option in rectal cancer?\",\"answer\":\"TAMIS is considered standard care because it is organ preserving, helping reduce morbidity associated with more radical proctectomy-based procedures.\"},{\"question\":\"Which patients are most suitable for curative TAMIS?\",\"answer\":\"TAMIS is indicated for early-stage rectal cancer (T1 with favorable pathology), including well/moderately differentiated adenocarcinoma, no lymphovascular invasion, and lesion size up to 3 cm.\"},{\"question\":\"How is recurrence and progression monitored after TAMIS?\",\"answer\":\"Regular follow-up with computed tomography imaging is required, and if the disease is upstaged to deeper layers (e.g., T2 or more), further transabdominal resection is warranted.\"}]","Transanal Minimally Invasive Surgery for Rectal Cancer - review article | PDF",1790216522]