[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-228389-en":3,"doc-seo-228389-105":30,"detail-sidebar-cat-0-en-105":97},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},228389,8796095462418,"Noah","https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780",8,"Research & Report","TOXICOLOGICAL PROFILE FOR PHOSPHATE ESTER FLAME RETARDANTS - ATSDR report","Toxicological profiles for phosphate ester flame retardants summarize and interpret toxicologic and adverse health effects information based on key peer-reviewed studies and relevant supporting literature. The profile framework presents a public health statement in nontechnical language, outlines levels of significant human exposure, and—where known—details significant acute, subacute, and chronic health effects. It also evaluates adequacy of data for health effect determination, identifies data needs for protecting public health, and highlights toxicological testing relevant to exposure types or levels that may pose risks.","TOXICOLOGICAL PROFILE FOR PHOSPHATE ESTER FLAME RETARDANTS  \nU. S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service  \nAgency for Toxic Substances and Disease Registry  \nSeptember 2012  \nPHOSPHATE ESTER FLAME RETARDANTS ii  \nDISCLAIMER  \nUse of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services.  \nPHOSPHATE ESTER FLAME RETARDANTS iii  \nUPDATE STATEMENT  \nA Toxicological Profile for Phosphate Ester Flame Retardants, Draft for Public Comment was released in September 2009. This edition supersedes any previously released draft or final profile.  \nToxicological profiles are revised and republished as necessary. For information regarding the update status of previously released profiles, contact ATSDR at:  \nAgency for Toxic Substances and Disease Registry Division of Toxicology and Human Health Sciences (proposed)  \nEnvironmental Toxicology Branch (proposed)  \n1600 Clifton Road NE  \nMailstop F-62  \nAtlanta, Georgia 30333  \nPHOSPHATE ESTER FLAME RETARDANTS iv  \nThis page is intentionally blank.  \nPHOSPHATE ESTER FLAME RETARDANTS v  \nFOREWORD  \nThis toxicological profile is prepared in accordance with guidelines* developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA) . The original guidelines were published in the Federal Register on April 17, 1987. Each profile will be revised and republished as necessary.  \nThe ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the toxic substances each profile describes. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicologic properties. Other pertinent literature is also presented but is described in less detail than the key studies. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced.  \nThe profiles focus on health and toxicologic information; therefore, each toxicological profile begins with a public health statement that describes, in nontechnical language, a substance's relevant toxicological properties. Following the public health statement is information concerning levels of significant human exposure and, where known, significant health effects. A health effects summary describes the adequacy of information to determine a substance's health effects. ATSDR identifies data needs that are significant to protection of public health.  \nEach profile:  \n(A) Examines, summarizes, and interprets available toxicologic information and epidemiologic evaluations on a toxic substance to ascertain the levels of significant human exposure for the substance and the associated acute, subacute, and chronic health effects;  \n(B) Determines whether adequate information on the health effects of each substance is available or being developed to determine levels of exposure that present a significant risk to human health of acute, subacute, and chronic health effects; and  \n(C) Where appropriate, identifies toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans.  \nThe principal audiences for the toxicological profiles are federal, state, and local health professionals; interested private sector organizations and groups; and members of the public.  \nThis profile reflects ATSDR’s assessment of all relevant toxicologic testing and information that has been peer-reviewed. Staff of the Centers for Disease Control and Prevention and other federal scientists also have reviewed the profile. In addition, this profile has been peer-reviewed by a nongovernmental panel and was made available for public review. Final responsibility for the contents and views expressed in this toxicological profile resides with ATSDR.  \nC","cbCaivnXIVe2ZDiA","https://ap.wps.com/l/cbCaivnXIVe2ZDiA","pdf",21948301,1,431,"English","en",105,"# Update Statement\n# Foreword\n## Purpose and Audience\n## Profile Structure and Review Approach\n# Legislative Background\n# Quick Reference for Health Care Providers","[{\"question\":\"What is the purpose of the ATSDR toxicological profile for phosphate ester flame retardants?\",\"answer\":\"It succinctly characterizes toxicologic and adverse health effects information by examining, summarizing, and interpreting available toxicologic and epidemiologic data, including key literature and peer-reviewed evaluations.\"},{\"question\":\"What structure does the profile follow to communicate information?\",\"answer\":\"It begins with a public health statement in nontechnical language, then covers levels of significant human exposure and, where known, significant health effects, followed by health effects summaries and data needs.\"},{\"question\":\"Who is the intended audience for the toxicological profile?\",\"answer\":\"Federal, state, and local health professionals, interested private sector organizations and groups, and members of the public, with additional quick-reference information for health care providers.\"}]","TOXICOLOGICAL PROFILE FOR PHOSPHATE ESTER FLAME RETARDANTS - 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