[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-406556-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-406556-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","timing-of-diverting-loop-ileostomy-closure-after-rectal-resection-commentary-on-recent-findings","Timing of diverting loop ileostomy closure after rectal resection: Commentary on recent findings","","Clinicians lack consensus on the optimal timing for reversing a loop ileostomy after rectal resection. Waiting 8–12 weeks can reduce concern for anastomotic complications, yet prolonged diversion may increase dehydration, electrolyte disturbances, stoma-related problems, and lower quality of life. Randomized trials and meta-analyses report mixed results and emphasize the need for careful selection. Evidence discussed suggests reversal within 2–4 weeks may be safe and beneficial in carefully chosen patients with an intact anastomosis and uneventful recovery, though existing data are limited by retrospective design and short follow-up; multicenter randomized studies are needed to standardize criteria and ensure long-term safety.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/timing-of-diverting-loop-ileostomy-closure-after-rectal-resection-commentary-on-recent-findings/406556/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/timing-of-diverting-loop-ileostomy-closure-after-rectal-resection-commentary-on-recent-findings/406556.png","ImageObject",300,407,{"name":42,"@type":43},"Dipper","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-05","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"Why is the timing of loop ileostomy reversal after rectal resection controversial?","Question",{"text":63,"@type":64},"Clinicians remain uncertain because delayed closure may better protect against anastomotic complications, but it can also worsen dehydration, electrolyte issues, stoma-related complications, and quality of life.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What rationale supports early closure compared with traditional delayed closure?",{"text":68,"@type":64},"Early closure aims to reduce diversion-related burdens and improve postoperative quality of life, especially when patients have intact anastomosis and an uneventful postoperative course.",{"name":70,"@type":61,"acceptedAnswer":71},"What limitations affect the evidence supporting early closure?",{"text":72,"@type":64},"Key supporting data include retrospective methods with short follow-up, and randomized trials/meta-analyses show heterogeneous results, highlighting the need for cautious patient selection and prospective validation.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},406556,1790882827,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":102,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144,"preview_page_count":4},1374404997633,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","| W | J | G | S | World Journal of\u003Cbr>Gastrointestinal Surgery |\n| --- | --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Surg 2025 December 27; 17(12): 114274  \nDOI: 10.4240/wjgs.v17.i12.114274 ISSN 1948-9366 (online)  \nLETTER TO THE EDITOR  \nTiming of diverting loop ileostomy closure after rectal resection: Commentary on recent findings  \nJasneet S Bhullar, Saleh A Busbait, Koby Herman, Gautham Chitragari, Jai P Singh, Ernesto R Drelichman  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade A, Grade B  \nNovelty: Grade B, Grade B  \nCreativity or Innovation: Grade B, Grade B  \nScientific Significance: Grade B, Grade B  \nP-Reviewer: Cheng XF, PhD, China  \nReceived: September 16, 2025  \nRevised: October 19, 2025  \nAccepted: October 30, 2025  \nPublished online: December 27, 2025  \nProcessing time: 101 Days and 8 Hours  \nJasneet S Bhullar, Saleh A Busbait, Koby Herman, Gautham Chitragari, Jai P Singh, Ernesto RDrelichman, Department of Surgery, Henry Ford Providence Hospital, Michigan State University College of Human Medicine, Southfield, MI 48075, United States  \nSaleh A Busbait, Department of Surgery, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia  \nCo-corresponding authors: Jasneet S Bhullar and Saleh A Busbait.  \nCorresponding author: Jasneet S Bhullar, Department of Surgery, Henry Ford Providence Hospital, Michigan State University College of Human Medicine, 16001 W Nine Mile Rd, Southfield, MI 48075, [United States.](United States. drjsbhullar@gmail.com)[ drjsbhullar@gmail.com](United States. drjsbhullar@gmail.com)  \nAbstract  \nThe clinicians remain uncertain about the ideal timing for loop ileostomy reversal following rectal resection surgery. The common practice of waiting 8-12 weeks to protect from anastomotic complication, especially in patients who receive neoadjuvant chemoradiotherapy, would expose patients to dehydration, electrolyte disturbances, stoma related complications, and reduced quality of life. Randomized controlled trials have studied early reversal of ileostomy, with results ranging from improved outcomes in selected patients to increased morbidity when applied indiscriminately. Meta-analyses have also yielded heterogeneous findings, reflecting the need for careful patient selection. The study by Özcan and Düzgün used retrospective methods to show that patients who underwent early closure experienced similar complication rates to those who had late closure, but early closure were associated with better quality of life. Taken together, current evidence suggests that reversal within 2-4 weeks may be safe and beneficial in meticulously selected patients with an intact anastomosis and an uneventful postoperative course. Their study provides practical data supporting early closure. It is limited, however, by being retrospective with a short follow-up period, which may leave important concerns unaddressed. Multicenter randomized trials are required to help establish safe standardized criteria for early closure and longterm safety.  \nKey Words: Loop ileostomy; Ileostomy closure; Rectal cancer; Quality of life; Anastomotic leak  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \n WJGS  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 27, 2025  Volume 17  Issue 12   \nBhulla JS et al. Commentary: Loop ileostomy closure timing  \nCore Tip: This commentary highlights that while traditional delayed closure protects the anastomosis, it imposes substantial patient burden. Recent retrospective data suggest that ultra-early (10-14 days) reversal may be safe and improve quality of life, but this aggressive strategy warrants cautious interpretation and prospective validation to define ideal candidates.  \nCitat","cbCaig95HhSvfdOD","https://ap.wps.com/l/cbCaig95HhSvfdOD","pdf",384635,"English","# Abstract\n# Core Tip\n# TO THE EDITOR","[{\"question\":\"Why is the timing of loop ileostomy reversal after rectal resection controversial?\",\"answer\":\"Clinicians remain uncertain because delayed closure may better protect against anastomotic complications, but it can also worsen dehydration, electrolyte issues, stoma-related complications, and quality of life.\"},{\"question\":\"What rationale supports early closure compared with traditional delayed closure?\",\"answer\":\"Early closure aims to reduce diversion-related burdens and improve postoperative quality of life, especially when patients have intact anastomosis and an uneventful postoperative course.\"},{\"question\":\"What limitations affect the evidence supporting early closure?\",\"answer\":\"Key supporting data include retrospective methods with short follow-up, and randomized trials/meta-analyses show heterogeneous results, highlighting the need for cautious patient selection and prospective validation.\"}]","Timing of diverting loop ileostomy closure after rectal resection: Commentary on recent findings | PDF",1790566431,15]