[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-31846":3,"doc-seo-31846":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},31846,2336464648746,"Skyler","https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c",8,"Research & Report","Three New Dihydrochalcones from the Leaves of Artocarpus Sericicarpus and Their Activity Against Plasmodium Falciparum","Three new dihydrochalcones, artoserichalcone A–C (1–3), were isolated from the leaves of Artocarpus sericicarpus. Compound structures were elucidated using NMR spectroscopy (1H, 13C, and 2D) together with HRESIMS analysis. Antimalarial testing against Plasmodium falciparum showed strong activity for compounds (1) and (3), with IC50 values of 16.90 and 13.56 µM, while compound (2) displayed moderate activity (IC50 63.01 µM). Cytotoxicity assessment on Huh7, HepG2, BHK-21, and Vero cells indicated non-cytotoxic behavior (CC50 > 20 µg/mL).","cbCaij6RZAlKs0Nr","https://ap.wps.com/l/cbCaij6RZAlKs0Nr","pdf",1574469,1,10,"English","en","# Introduction\n# Results and discussion","[{\"question\":\"What compounds were isolated from Artocarpus sericicarpus leaves?\",\"answer\":\"Three new dihydrochalcones—artoserichalcone A–C (1–3)—were isolated from the leaves of Artocarpus sericicarpus.\"},{\"question\":\"How were the structures of the isolated compounds determined?\",\"answer\":\"The structures were determined using NMR spectroscopy (1H, 13C, and 2D) and HRESIMS spectroscopic analysis.\"},{\"question\":\"What antimalarial activity was observed against Plasmodium falciparum?\",\"answer\":\"Compounds (1) and (3) showed active antimalarial activity with IC50 values of 16.90 µM and 13.56 µM, while compound (2) showed moderate activity with an IC50 of 63.01 µM.\"}]",1780261384,25,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"three-new-dihydrochalcones-from-the-leaves-of-artocarpus-sericicarpus-and-their-activity-against-plasmodium-falciparum","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/research-report/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/three-new-dihydrochalcones-from-the-leaves-of-artocarpus-sericicarpus-and-their-activity-against-plasmodium-falciparum/31846/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-05-31",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"What compounds were isolated from Artocarpus sericicarpus leaves?","Question",{"text":73,"@type":74},"Three new dihydrochalcones—artoserichalcone A–C (1–3)—were isolated from the leaves of Artocarpus sericicarpus.","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"How were the structures of the isolated compounds determined?",{"text":78,"@type":74},"The structures were determined using NMR spectroscopy (1H, 13C, and 2D) and HRESIMS spectroscopic analysis.",{"name":80,"@type":71,"acceptedAnswer":81},"What antimalarial activity was observed against Plasmodium falciparum?",{"text":82,"@type":74},"Compounds (1) and (3) showed active antimalarial activity with IC50 values of 16.90 µM and 13.56 µM, while compound (2) showed moderate activity with an IC50 of 63.01 µM.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]