[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-456434-105":59,"doc-detail-456434-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","therapeutic-potential-of-adipose-tissue-in-aesthetic-medicine-review","Therapeutic potential of adipose tissue in aesthetic medicine - review","","Aesthetic medicine focuses on improving appearance and overall visual appeal, yet conventional interventions can cause complications, allergic reactions, infections, granulomas, ischemia, and anesthesia-related risks while often providing only temporary benefits. Adipose tissue is presented as a promising alternative because of its regenerative properties, accessibility, and versatility. It contains adipose-derived stem cells, growth factors, and extracellular matrix, enabling repair of damaged and aged tissues, and supports multiple therapeutic formats including grafts, stromal vascular fraction, nanofat, macrofat, microfat, and ASC-derived exosomes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/therapeutic-potential-of-adipose-tissue-in-aesthetic-medicine-review/456434/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/therapeutic-potential-of-adipose-tissue-in-aesthetic-medicine-review/456434.png","ImageObject",300,407,{"name":92,"@type":93},"SANS","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is adipose tissue considered a promising alternative in aesthetic medicine?","Question",{"text":112,"@type":113},"Adipose tissue is valued for its regenerative properties, accessibility, and versatility, offering more natural and potentially longer-lasting aesthetic outcomes than conventional treatments.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What therapeutic formats of adipose tissue are discussed?",{"text":117,"@type":113},"The review describes multiple formats including pure adipose tissue grafts, stromal vascular fraction, nanofat, macrofat, microfat, and therapies using a pure population of adipose-derived stem cells.",{"name":119,"@type":110,"acceptedAnswer":120},"What challenges and future directions are highlighted?",{"text":121,"@type":113},"The review notes limitations such as variability in graft survival and regulatory challenges, emphasizing the need for further research to fully realize adipose tissue-based therapies for aesthetic treatments.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},456434,1791097161,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090760505,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","| W | J | E | M | World Journal of\u003Cbr>Experimental Medicine |\n| --- | --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Exp Med 2025 September 20; 15(3): 106641  \nDOI: 10.5493/wjem.v15.i3.106641 ISSN 2220-315x (online)  \n\n| Therapeutic potential of adipose tissue in aesthetic medicine\u003Cbr>Mahmood S Choudhery, Taqdees Arif, Aleeza Afzal, Ruhma Mahmood | REVIEW |\n| --- | --- |\n\nSpecialty type: Medicine, research and experimental  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade B, Grade B  \nNovelty: Grade B, Grade B  \nCreativity or Innovation: Grade B, Grade B  \nScientific Significance: Grade B, Grade C  \nP-Reviewer: Nagamine T  \nReceived: March 4, 2025  \nRevised: April 2, 2025  \nAccepted: May 10, 2025  \nPublished online: September 20, 2025  \nProcessing time: 162 Days and 1.1 Hours  \nMahmood S Choudhery, Taqdees Arif, Department of Human Genetics and Molecular Biology, University of Health Sciences Lahore, Lahore 54000, Pakistan  \nAleeza Afzal, Department of Biomedical Sciences, University of Health Sciences Lahore, Lahore 54000, Pakistan  \nRuhma Mahmood, Department of Paediatric Surgery, Allama Iqbal Medical College, Lahore 54000, Pakistan  \nCorresponding author: Mahmood S Choudhery, Department of Human Genetics and Molecular Biology, University of Health Sciences Lahore, Lahore 54000, [Pakistan.](Pakistan. ms20031@yahoo.com)[ ms20031@yahoo.com](Pakistan. ms20031@yahoo.com)  \nAbstract  \nAesthetic medicine is a branch of medicine dedicated to improve an individual’s appearance and overall visual appeal. Conventional aesthetic treatments have limitations, including the risk of complications, allergic reactions, and temporary benefits. Adipose tissue offers a promising alternative to conventional aesthetic treatments. The regenerative properties, accessibility and versatility of adipose tissue make it an attractive option for individuals seeking natural and long-lasting aesthetic results. Adipose tissue is rich source of adipose tissue derived stem cells (ASCs), growth factors and extracellular matrix. It can restore and rejuvenate the damaged and aged tissues. Adipose tissue can be used in different formats such as pure adipose tissue grafts, stromal vascular fraction, nanofat, macrofat, microfat and as a pure population of ASCs. In addition, ASC derived exosomes offera unique cell-free therapy advantages bioactive molecules like growth factors, cytokines, and microRNAs to stimulate collagen production, improve skin texture, and address pigmentation issues. This review highlights the multifaceted potential of adipose tissue in aesthetic medicine. It discusses its diverse applications, the biological mechanisms involved, and emerging therapeutic approaches. Moreover, this review also highlights the challenges and future direction of using adipose tissue-based therapies for aesthetic treatments.  \nKey Words: Aesthetic medicine; Adipose tissue; Autologous fat grafting; Regenerative aesthetics; Nanofat  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \n WJEM  [https://www.wjgnet.com](https://www.wjgnet.com) 1 September 20, 2025  Volume 15  Issue 3   \nChoudhery MS et al. Adipose tissue in aesthetic medicine  \nCore Tip: Aesthetic medicine has evolved with innovative solutions for improvement of overall appearance. Adipose tissue, with its regenerative properties, offers a promising alternative to traditional treatments. Adipose tissue derivatives such as nanofat, microfat, adipose tissue-derived stem cells, and stromal vascular fraction have shown therapeutic applications in aesthetic medicine. Studies demonstrate their effectiveness in treating acne scars, burn wounds, hyperpigmentation, wrinkles, and skin rejuvenation. However, limitations such as graft survival variability and regulatory challenges need to be","cbCaiqZpj6TSS7gJ","https://ap.wps.com/l/cbCaiqZpj6TSS7gJ","pdf",1258647,15,"English","# Abstract\n# Core Tip\n# Introduction","[{\"question\":\"Why is adipose tissue considered a promising alternative in aesthetic medicine?\",\"answer\":\"Adipose tissue is valued for its regenerative properties, accessibility, and versatility, offering more natural and potentially longer-lasting aesthetic outcomes than conventional treatments.\"},{\"question\":\"What therapeutic formats of adipose tissue are discussed?\",\"answer\":\"The review describes multiple formats including pure adipose tissue grafts, stromal vascular fraction, nanofat, macrofat, microfat, and therapies using a pure population of adipose-derived stem cells.\"},{\"question\":\"What challenges and future directions are highlighted?\",\"answer\":\"The review notes limitations such as variability in graft survival and regulatory challenges, emphasizing the need for further research to fully realize adipose tissue-based therapies for aesthetic treatments.\"}]","Therapeutic potential of adipose tissue in aesthetic medicine - review | PDF",1790746008,38]