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Their therapeutic potential in oral healthcare is reviewed across roles in maintaining oral health, promoting wound healing, and providing antibacterial effects that support tooth remineralization. Anti-inflammatory activity helps manage gingivitis, periodontitis, and oral ulcerations, while antibacterial and antifungal effects suppress key oral pathogens such as Streptococcus mutans. Carrageenan-based biodegradable films are highlighted for controlled drug delivery and tissue-regenerative biomaterials, and seaweed-derived oral hygiene products are discussed. Clinical translation needs larger, well-designed trials to confirm efficacy and safety.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/therapeutic-applications-of-red-marine-seaweeds-in-dental-care-innovations-in-oral-health-and-treatment/418578/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/therapeutic-applications-of-red-marine-seaweeds-in-dental-care-innovations-in-oral-health-and-treatment/418578.png","ImageObject",300,407,{"name":92,"@type":93},"WPS_1786070896","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What therapeutic benefits do red marine seaweeds provide in dental care?","Question",{"text":112,"@type":113},"They support oral health maintenance, wound healing, and tooth remineralization. They also show antibacterial, antifungal, and anti-inflammatory activities relevant to oral diseases.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which compounds in red marine seaweeds are emphasized for oral healthcare?",{"text":117,"@type":113},"The review highlights carrageenan, agar, collagen, alginate, and sulfated polysaccharides such as carrageenan and fucoidan, alongside proteins and phenolic compounds contributing to antimicrobial and anti-inflammatory effects.",{"name":119,"@type":110,"acceptedAnswer":120},"How might seaweed-derived materials be used beyond direct clinical therapy?",{"text":121,"@type":113},"Red seaweeds can be used to create carrageenan-based biodegradable films for controlled drug delivery and tissue-regenerative biomaterials. They can also serve as sustainable sources for naturally derived oral hygiene products such as mouthwashes, toothpastes, and gels.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},418578,1790890728,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},549768072016,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Research article  \nTherapeutic applications of red marine seaweeds in dental care: innovations in oral health and treatment  \nSivakamavalli Jeyachandran  \nLab in Biotechnology and Biosignal Transduction, Department of Orthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India  \nABSTRACT  \nRed marine seaweeds, particularly those belonging to the genus Rhodophyta, possess a robust structural framework and are rich in biologically active compounds such as carrageenan, agar, collagen, and alginate. These natural resources are abundant and have attracted significant attention for their therapeutic potential in oral healthcare. This review highlights the applications of red marine seaweeds in dentistry, focusing on their roles in maintaining oral health, facilitating wound healing, exhibiting antibacterial properties, and contributing to tooth remineralization. Notably, their anti-inflammatory activity supports the management of conditions such as gingivitis, periodontitis, and oral ulcerations, while their antibacterial and antifungal actions effectively inhibit oral pathogens such as Streptococcus mutans, a primary contributor to dental caries. Furthermore, carrageenan-based biodegradable films derived from red seaweeds demonstrate promising potential as controlled drug delivery systems and tissue-regenerative biomaterials within the oral cavity. Beyond clinical applications, seaweeds can also serve as sustainable sources for formulating naturally derived oral hygiene products – including mouthwashes, toothpastes, and gels – offering ecofriendly alternatives to synthetic chemicals. However, despite these advances, broader clinical adoption requires comprehensive and well-designed clinical trials to validate efficacy and safety. Overall, this review underscores the emerging potential of red marine seaweeds as sustainable, bioactive resources for innovative dental therapeutics, while emphasizing the need for continued translational and clinical research.  \nARTICLE HISTORY  \nReceived 30 June 2025 Accepted 10 November 2025  \nKEYWORDS  \nRed marine seaweeds; dental care; therapeutic applications; carrageenan; oral health; antimicrobial properties  \nIntroduction  \nThe growing demand for natural, sustainable, and biocompatible materials in dentistry has accelerated research into alternatives to conventional synthetic biomaterials. Among these, red marine seaweeds (Rhodophyta) have emerged as promising candidates due to their abundance, structural diversity, and wealth of bioactive compounds. Coastal ecosystems host over 7,000 species of red algae, many of which contain polysaccharides such as carrageenan, agar, and fucoidan, along with proteins and lipids that contribute to their biomedical potential (Ahmad et al., 2022; Carpena et al., 2023) . These compounds exhibit antimicrobial, anti-inflammatory, and regenerative properties, making them attractive for applications in oral health and dental therapeutics (Liyanage et al., 2023) . In dentistry, red seaweed-derived biomaterials show potential in multiple areas, including periodontal tissue regeneration, wound healing, oral biofilms inhibition, and caries prevention. Sulfated polysaccharides like carrageenan and fucoidan, in particular, have demonstrated strong antibacterial effects against oral pathogens such as Streptococcus mutans, as well as significant tissue-repairing capabilities (Dou et al., 2023; Thitame et al., 2025). Their natural biocompatibility and biodegradability further position them as  \neco-friendly alternatives to petroleum-based and chemically synthesized dental materials, aligning with the expanding market for sustainable dental products (Das & Bal, 2024; Martin & Mulligan, 2022) .  \nThis review aims to provide a comprehensive overview of the therapeutic potential of red marine seaweeds in dental care. It explores their role in antimicrobial defense, anti-inflammat","cbCairFp0PAoHi7w","https://ap.wps.com/l/cbCairFp0PAoHi7w","pdf",1904736,13,"English","# Abstract\n# Introduction\n# Dentistry and the antimicrobial properties of red marine seaweeds","[{\"question\":\"What therapeutic benefits do red marine seaweeds provide in dental care?\",\"answer\":\"They support oral health maintenance, wound healing, and tooth remineralization. They also show antibacterial, antifungal, and anti-inflammatory activities relevant to oral diseases.\"},{\"question\":\"Which compounds in red marine seaweeds are emphasized for oral healthcare?\",\"answer\":\"The review highlights carrageenan, agar, collagen, alginate, and sulfated polysaccharides such as carrageenan and fucoidan, alongside proteins and phenolic compounds contributing to antimicrobial and anti-inflammatory effects.\"},{\"question\":\"How might seaweed-derived materials be used beyond direct clinical therapy?\",\"answer\":\"Red seaweeds can be used to create carrageenan-based biodegradable films for controlled drug delivery and tissue-regenerative biomaterials. They can also serve as sustainable sources for naturally derived oral hygiene products such as mouthwashes, toothpastes, and gels.\"}]","Therapeutic applications of red marine seaweeds in dental care - innovations in oral health and treatment | PDF",1790613609,33]