[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-508652-105":59,"doc-detail-508652-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","the-use-of-fecal-calprotectin-testing-in-paediatric-disorders-position-paper-jpgn-2021","The Use of Fecal Calprotectin Testing in Paediatric Disorders - Position Paper - JPGN 2021","","A position paper reviews evidence for the clinical use and value of faecal calprotectin (FC) measurements across paediatric gastrointestinal disorders. A literature search in PubMed, MEDLINE, EMBASE, and Cochrane up to October 31, 2019 supported 28 recommendations generated by nominal voting. Consensus addressed sampling, testing methods, and interpretation, while noting limitations from variability in extraction, kit performance, and the need for local reference ranges. FC is mainly useful for diagnosing and monitoring inflammatory bowel disease.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-use-of-fecal-calprotectin-testing-in-paediatric-disorders-position-paper-jpgn-2021/508652/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-use-of-fecal-calprotectin-testing-in-paediatric-disorders-position-paper-jpgn-2021/508652.png","ImageObject",300,407,{"name":92,"@type":93},"PakDamar76","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-09","2026-10-05",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the goal of the position paper on faecal calprotectin testing in children?","Question",{"text":112,"@type":113},"To review evidence for the clinical use and value of faecal calprotectin measurements in different paediatric gastrointestinal disorders.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were the recommendations developed and when was the evidence searched?",{"text":117,"@type":113},"Recommendations were created using nominal voting on 28 items, supported by a literature search in PubMed, MEDLINE, EMBASE, and Cochrane up to October 31, 2019.",{"name":119,"@type":110,"acceptedAnswer":120},"For which paediatric conditions is faecal calprotectin most useful according to the paper?",{"text":121,"@type":113},"Its main utility is in the diagnosis and monitoring of inflammatory bowel disease and in differentiating IBD from functional gastrointestinal disorders.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},508652,1791322258,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":26,"preview_page_count":4},962090893057,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","The Use of Fecal Calprotectin Testing in Paediatric Disorders: A Position Paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology Committee  \n􀀂 Carmen Ribes Koninckx, 􀀂Ester Donat, yMarc A. Benninga, zIlse J. Broekaert,  \n§Frederic Gottrand, jj Kaija-Leena Kolho, 􀀂Paolo Lionetti, \\#Erasmo Miele, 􀀂􀀂Rok Orel,  \nyyAlexandra Papadopoulou, zz Corina Pienar, §§Michela G. Scha¨ppi,  \njj jjMichael Wilschanski, and 􀀂􀀂\\#\\#Nikhil Thapar  \nABSTRACT  \nObjectives: The aim of the study was to review the evidence regarding the clinical use and value of faecal calprotectin (FC) measurements in different gastrointestinal disorders in children.  \nMethods: A literature search was conducted in the PubMed, MEDLINE, EMBASE, and Cochrane databases until October 31, 2019 . Subtopics were identified and each assigned to individual authors.  \nResults: A total of 28 recommendations were voted on using the nominal voting technique. Recommendations are given related to sampling, measurement methods, and results interpretation. The 14 authors anonymously voted on each recommendation using a 9-point scale (1 strongly disagree to 9 fully agree) . Consensus was considered achieved if at least 75% of the authors voted 6, 7, 8, or 9 .  \nConclusions: Consensus was reached for all recommendations. Limitations for the use ofFC in clinical practice include variability in extraction methodology, performance of test kits as well as the need to establish local reference ranges because ofthe influence of individual factors, such as age, diet, microbiota, and drugs. The main utility of FC measurement at present is in the diagnosis and monitoring of inflammatory bowel disease (IBD) as well as to differentiate it from functional gastrointestinal disorders (FAPDs). FC, however, has neither utility in the diagnosis of infantile colic nor to differentiate between functional and organic constipation. A rise in FC concentration, may alert to the risk of developing necrotizing enterocolitis and help identifying gastrointestinal involvement in children with Henoch-Scho¨nlein purpura. FC measurement is of little value in Cow’s Milk Protein Allergy, coeliac disease (CD), and cystic fibrosis. FC doesneither help to distinguish bacterial from viral acute gastroenteritis (AGE), nor to diagnose Helicobacter Pylori infection, small intestinal bacterial overgrowth (SIBO), acute appendicitis (AA), or intestinal polyps.  \nKey Words: Crohn disease, fecal calprotectin, inflammation, inflammatory  \nbowel disease, intestine, position paper, ulcerative colitis (JPGN 2021;72: 617–640)  \nReceived July 19, 2020; accepted December 8, 2020 .  \nFrom the 􀀂Department of Paediatric Gastroenterology, Hepatology and Nutrition, La Fe University Hospital Valencia, Spain, the y Department of Paediatric Gastroenterology and Nutrition, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands, the z Department of Paediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, the § Department of Paediatric Gastroenterology, Hepatology and Nutrition, CHU Lille, University Lille, France, the jj Children’s Hospital, University of Helsinki, Helsinki, Finland and Tampere University, Tampere, Finland, the 􀀂 Department NEUROFARBA, University of Florence - Meyer Children’s Hospital, Florence, the \\#Department of Translational Medical Science, Section of Pediatrics, University of Naples ’’Federico II’’, Naples, Italy, the 􀀂􀀂Department of Gastroenterology, Hepatology and Nutrition, University  \nWhat Is Known  \n􀀃 Limitations to the interpretation offaecal calprotectin results include variability in extraction methodology, performance of test kits, and the need to establish local reference ranges.  \n􀀃 The main utility of faecal calprotectin measurement at present is in the screening and monitoring of inflammatory bowel disease.  \nWhat Is New?  \n􀀃 Although faecal calprotectin may be considered as a tool to different","cbCaif84gKsj00uB","https://ap.wps.com/l/cbCaif84gKsj00uB","pdf",412134,24,"English","# Abstract\n## Objectives\n## Methods\n## Results\n## Conclusions\n# What Is Known\n# What Is New\n# Introduction","[{\"question\":\"What was the goal of the position paper on faecal calprotectin testing in children?\",\"answer\":\"To review evidence for the clinical use and value of faecal calprotectin measurements in different paediatric gastrointestinal disorders.\"},{\"question\":\"How were the recommendations developed and when was the evidence searched?\",\"answer\":\"Recommendations were created using nominal voting on 28 items, supported by a literature search in PubMed, MEDLINE, EMBASE, and Cochrane up to October 31, 2019.\"},{\"question\":\"For which paediatric conditions is faecal calprotectin most useful according to the paper?\",\"answer\":\"Its main utility is in the diagnosis and monitoring of inflammatory bowel disease and in differentiating IBD from functional gastrointestinal disorders.\"}]","The Use of Fecal Calprotectin Testing in Paediatric Disorders - Position Paper - JPGN 2021 | PDF",1791231173]