[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-406003-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-406003-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","the-risk-analysis-of-unplanned-tracheal-intubation-after-radical-esophagectomy","The risk analysis of unplanned tracheal intubation after radical esophagectomy","","Esophageal cancer patients often face high perioperative risk, and unplanned tracheal intubation can substantially worsen clinical outcomes. This retrospective real-world study analyzed 463 patients who underwent surgery at Zhejiang Cancer Hospital in 2019 to identify independent risk factors for postoperative reintubation. Unplanned reintubation occurred in 7.8% (36/463), mainly driven by respiratory failure and pulmonary infection. Multivariable logistic regression showed the analgesic technique as an independent risk factor, with significant associations compared with general anesthesia plus epidural 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of unplanned tracheal intubation after radical esophagectomy  \nJunbo Yuan1,2, Yimin Wu1,2, Yun Cheng1, Weikang Zhang1, Zewu Ding1, Man Fang1, Shunv Cai1􀀍 & Xinyi Liu1􀀍  \nEsophageal cancer patients often face various challenges in the perioperative period, and unplanned tracheal intubation is a serious complication that can significantly impact patient outcomes. Therefore, this study aimed to identify the risk factors for reintubation in esophageal cancer patients after surgery. A retrospective study was carried out on esophageal cancer patients who underwent surgery at Zhejiang Cancer Hospital in 2019. Data on patient demographics, surgical details, and anesthesia techniques were collected. We employed logistic regression analysis to explore the factors associated with the occurrence of unplanned tracheal intubation. The study encompassed a total of 463 patients. 7.8%(36/463) of the enrolled patients encountered unplanned reintubation during the postoperative phase. Notably, respiratory failure (9/49, 18.4%) and pulmonary infection (8/49, 16.3%) emerged as the primary drivers prompting patients to undergo reintubation in the postoperative period. The results of multivariable logistic analysis indicated that analgesic technique was the independent risk factor for reintubation and compared with general anesthesia (GA) combined with epidural anesthesia, GA combined with nerve block was significantly associated with reintubation.  \nThis study analyzed the incidence of unplanned tracheal intubation in esophageal cancer patients after surgery and determined the key independent risk factors.  \nKeywords Unplanned tracheal intubation, Analgesic technique, Esophageal cancer, Real-word study, Perioperative management  \nAbbreviations  \nGA General anesthesia  \nOR The odds ratio  \nCI Confidence interval  \nIQR The interquartile range  \nPACU Post-anesthetic care unit INB Intercostal nerve block  \nTAP Transversus abdominis plane block  \nMV Ventilation volume  \nVE Minute ventilation volume  \nV/Q Ventilation/perfusion  \nTEA Thoracic epidural anesthesia ERAS Enhanced recovery after surgery IPTW Inverse probability weighting  \nEsophageal cancer, a common digestive tract malignancy worldwide, has a relatively high incidence and ranks seventh among the leading causes of cancer - related deaths1. Currently, although radiotherapy and chemotherapy have made rapid progress, surgery still plays a crucial part in the comprehensive treatment of esophageal cancer2,3. However, due to complex procedures involved in esophageal surgery, such as alterations to the intrathoracic environment, a series of severe complications often follow after the operation, posing a huge challenge to patients’ recovery4,5. Therefore, it is of utmost importance to meticulously manage the perioperative process to help patients avoid complications following esophageal surgery.  \n1Department of Anesthesiology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, No. 1, Banshan East Road, Gongshu District, Hangzhou 310022, P. R. China. 2Junbo Yuan andYimin Wu contributed equally to this work. 􀀍 email: [caisn@zjcc.org.cn](caisn@zjcc.org.cn); [liuxy@zjcc.org.cn](liuxy@zjcc.org.cn)  \n[www. nature.com/scientificreports/](www. nature.com/scientificreports/)  \nReintubation, a severe postoperative complication6,7, refers to intubation after extubation ofa patient initially tracheally intubated under general anesthesia or in combination with other analgesic techniques8. Numerous factors are related to postoperative reintubation, including the patient’s preoperative physical condition, surgical procedures, and perioperative anesthesia management. In clinical practice, when the topic of reintubation arises, it is often linked to serious respiratory disorders, such as acute hypoxemia, hypercapnia, respiratory failure and airway obstruction9–11. There is a stri","cbCaif4kqpmyC3fO","https://ap.wps.com/l/cbCaif4kqpmyC3fO","pdf",2023143,11,"English","# Abstract\n# Methods\n## Study population","[{\"question\":\"What was the primary goal of this study?\",\"answer\":\"To identify risk factors for reintubation in esophageal cancer patients after surgery, focusing on unplanned tracheal intubation.\"},{\"question\":\"How common was unplanned reintubation in the studied cohort?\",\"answer\":\"Unplanned reintubation occurred in 7.8% (36/463) of the enrolled patients during the postoperative phase.\"},{\"question\":\"Which factor was identified as an independent risk factor for reintubation?\",\"answer\":\"The analgesic technique was identified as the independent risk factor for reintubation.\"}]","The risk analysis of unplanned tracheal intubation after radical esophagectomy | PDF",1790563024,28]