[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-424192-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-424192-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","the-impact-of-the-interaction-between-sarcopenia-and-frailty-on-mortality-in-older-adult-with-cardiovascular-disease","THE IMPACT OF THE INTERACTION BETWEEN SARCOPENIA AND FRAILTY ON MORTALITY IN OLDER ADULT WITH CARDIOVASCULAR DISEASE","","Longitudinal evidence from 496 older adults with cardiovascular disease evaluates sarcopenia and physical frailty and their combined effect on mortality. Sarcopenia was diagnosed using the SDOC recommendation and frailty via the Hopkins criteria at baseline; mortality was assessed by telephone at 6, 12, and 18 months with Cox regression. Mortality was 8.1%, and among deaths, frailty and sarcopenia were both common. The interaction was significant (p \u003C 0.001), with frailty and sarcopenia showing comparable adjusted hazard ratios.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/the-impact-of-the-interaction-between-sarcopenia-and-frailty-on-mortality-in-older-adult-with-cardiovascular-disease/424192/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/the-impact-of-the-interaction-between-sarcopenia-and-frailty-on-mortality-in-older-adult-with-cardiovascular-disease/424192.png","ImageObject",300,407,{"name":42,"@type":43},"Stanford","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-04","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",8,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What was the study objective regarding sarcopenia and frailty?","Question",{"text":63,"@type":64},"To assess whether sarcopenia and frailty predict mortality in older adults with cardiovascular disease and whether an interaction exists between them.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How were sarcopenia and frailty diagnosed in the study?",{"text":68,"@type":64},"Sarcopenia was diagnosed using the SDOC recommendation, and frailty was diagnosed using the Hopkins criteria at the beginning of the study.",{"name":70,"@type":61,"acceptedAnswer":71},"What timing and method were used to assess mortality?",{"text":72,"@type":64},"Mortality was assessed by telephone follow-up at 6, 12, and 18 months.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},424192,1790767864,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":111,"show_sort_weight":112,"slug":113},"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":22,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":30,"preview_page_count":4},2336477552062,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Innovation in Aging, 2025, Vol. 9, No. S2 855  \nepidemiological study on sarcopenia and osteoporosis for mortality in the older adults with CVD. Ethic committee CAE:24412713.6.0000.5505. Sarcopenia was diagnosed by the SDOC recommendation and frailty by the Hopkins criteria atthe beginning of the study. Mortality was assessed by telephone call at 6-12-18 months. Survival analyses were performed by Cox regression (p \u003C 0.08) . Results: In 496 subjects, the mean age was  \n77.85 (±7.8) and 56.7% were women (p.ns). The mortality rate was 8.1%(n = 40), and among those who died, 67.5%(n = 27) had frailty, 27.5% (n = 11) pre-frailty (p \u003C 0.001) and 65%(n = 26) sarcopenia (p = 0.001) . Heart failure, atrial fibrillation, CRF, age, stroke, hospitalizations, falls, and alcohol consumption were also associated with mortality (p \u003C 0.05) . The interaction between sarcopenia and frailty was significant (p \u003C 0.001) . In the adjusted multivariate analysis for the variables and the interaction between sarcopenia and frailty, frailty showed HR: 4.16 (1.12-15.42; p = 0.033) and sarcopenia HR: 4.13 (0.95-17.95; p = 0.058) . In the subtraction model of the non-significant variables frailty remained significant with HR 3.80 (1.11-13.01; p = 0.033) . Conclusions: In older adults with CVDs, frailty and sarcopenia had similar mortality risk values, regardless of the interaction between them  \nAbstract citation ID: igaf122.2895  \nTHE IMPACT OF THE INTERACTION BETWEEN  \nSARCOPENIA AND FRAILTY ON MORTALITY IN  \nOLDER ADULT WITH CARDIOVASCULAR DISEASE  \nAlberto Frisoli, Amanda Diniz, and Giovana Menin, Universidade Federal de Sao Paulo, São Paulo, Sao Paulo, Brazil  \nIntroduction: Sarcopenia and physical frailty are very prevalent in the elderly with cardiovascular disease (CVD) and increase the risk of mortality. However, it is still unclear whether there isan interaction between them in relation to mortality or whether they act independently. Objective: To assess the predictive value of sarcopenia and frailty in the mortality of older adults with CVD. Methods: Longitudinal analysis of SARCOS, an","cbCaiip5BoxBNGVU","https://ap.wps.com/l/cbCaiip5BoxBNGVU","pdf",766168,"English","# Study objective\n# Methods\n## Population and diagnoses\n## Mortality assessment\n# Results\n## Mortality and baseline characteristics\n## Predictors and interaction\n# Conclusions","[{\"question\":\"What was the study objective regarding sarcopenia and frailty?\",\"answer\":\"To assess whether sarcopenia and frailty predict mortality in older adults with cardiovascular disease and whether an interaction exists between them.\"},{\"question\":\"How were sarcopenia and frailty diagnosed in the study?\",\"answer\":\"Sarcopenia was diagnosed using the SDOC recommendation, and frailty was diagnosed using the Hopkins criteria at the beginning of the study.\"},{\"question\":\"What timing and method were used to assess mortality?\",\"answer\":\"Mortality was assessed by telephone follow-up at 6, 12, and 18 months.\"}]","THE IMPACT OF THE INTERACTION BETWEEN SARCOPENIA AND FRAILTY ON MORTALITY IN OLDER ADULT WITH CARDIOVASCULAR DISEASE | PDF",1790633279]