[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-426205-105":59,"doc-detail-426205-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","the-fragile-path-resilience-and-frailty-dynamics-in-hip-fracture-recovery","THE FRAGILE PATH - Resilience and Frailty Dynamics in Hip Fracture Recovery","","Hip fractures act as a major stressor that exposes resilience deficits, especially among frail individuals. The study tracks frailty trajectories around hip fracture and tests their combined effects on mortality using 4,963 UK Biobank participants. Frailty is measured monthly for 12 months before and after fracture with the Hospital Frailty Risk Score. Latent class models and multinomial logistic regression assess trajectories and transitions, while survival analysis links trajectories to death.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-fragile-path-resilience-and-frailty-dynamics-in-hip-fracture-recovery/426205/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-fragile-path-resilience-and-frailty-dynamics-in-hip-fracture-recovery/426205.png","ImageObject",300,407,{"name":92,"@type":93},"Stanford","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-20","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How is frailty measured in the study?","Question",{"text":112,"@type":113},"Frailty is assessed monthly for 12 months before and after hip fracture using the Hospital Frailty Risk Score derived from ICD-10 codes.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What frailty trajectories are found before the hip fracture?",{"text":117,"@type":113},"Before fracture, three trajectories are identified: persistently robust (44.2%), moderately frail (37.1%), and progressively frail (18.7%).",{"name":119,"@type":110,"acceptedAnswer":120},"How do these trajectories relate to post-fracture outcomes and death?",{"text":121,"@type":113},"Pre- and post-fracture frailty trajectories are independently and jointly associated with mortality, with higher pre-fracture frailty linked to greater post-fracture severity and higher death risk within the same post-fracture category.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},426205,1790794480,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24},2336477552062,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Innovation in Aging, 2025, Vol. 9, No. S2 313  \nAbstract citation ID: igaf122.1057  \nTHE FRAGILE PATH: RESILIENCE AND FRAILTY DYNAMICS IN HIP FRACTURE RECOVERY  \nChenkai Wu1, Jianhong Xu1, Yanxin Wang1, Jonathan Ka-Long Mak2, Emiel O. Hoogendijk3, and Graciela Muniz-Terrera4, 1. Duke Kunshan University, Kunshan, Jiangsu, China (People’s Republic), 2. The University of Hong Kong, Hong Kong, China (People’s Republic), 3. VU University Medical Center, Amsterdam, Noord-Holland, Netherlands, 4. University of Edinburgh, Edinburgh, Scotland, United Kingdom  \nHip fractures represent a significant stressor, revealing underlying resilience deficits, particularly in frail individuals. This study examines frailty trajectories surrounding hip fracture and their joint impact on mortality. Using data from 4,963 UK Biobank participants with incident hip fracture, we assessed frailty monthly via the Hospital Frailty Risk Score (derived from ICD-10 codes) for 12 months before and after hip fracture. Latent class trajectory models identified distinct frailty trajectories 12 months before and after hip fracture, separately. We used the multinomial logistic regression to examine transitions between pre-and post-fracture frailty trajectories. Survival analysis was used to determine the association between the trajectories and death. We identified three frailty trajectories in the  \n12 months before hip fracture: persistently robust (44.2%), moderately frail (37.1%), and progressively frail (18.7%). Frailty remained stable except in the progressively frail group, where frailty scores increased by 28.6% in the year before fracture. After hip fracture, three distinct trajectories emerged: moderate frailty with stability (63.0%), high frailty with stability (30.8%), and rapidly progressive frailty (6.2%). Higher pre-fracture frailty was strongly linked to greater post-fracture frailty severity. Preand post-fracture frailty trajectories were independently and jointly associated with death; higher pre-fracture frailty was linked to higher mortality within the same post-fracture category. These findings demonstrate distinct frailty trajectories surrounding hip fracture, highlighting the predictive value of pre-fracture  \n314 Innovation in Aging, 2025, Vol. 9, No. S2  \nfrailty for post-fracture outcomes and mortality. Identifying high-risk individuals through these trajectories can inform targeted interventions to improve recovery and survival.","cbCaiisI9e2jZ5cl","https://ap.wps.com/l/cbCaiisI9e2jZ5cl","pdf",620290,"English","# Abstract\n## Study design and data\n## Frailty trajectory identification\n## Associations with mortality\n## Implications for intervention","[{\"question\":\"How is frailty measured in the study?\",\"answer\":\"Frailty is assessed monthly for 12 months before and after hip fracture using the Hospital Frailty Risk Score derived from ICD-10 codes.\"},{\"question\":\"What frailty trajectories are found before the hip fracture?\",\"answer\":\"Before fracture, three trajectories are identified: persistently robust (44.2%), moderately frail (37.1%), and progressively frail (18.7%).\"},{\"question\":\"How do these trajectories relate to post-fracture outcomes and death?\",\"answer\":\"Pre- and post-fracture frailty trajectories are independently and jointly associated with mortality, with higher pre-fracture frailty linked to greater post-fracture severity and higher death risk within the same post-fracture category.\"}]","THE FRAGILE PATH - Resilience and Frailty Dynamics in Hip Fracture Recovery | PDF",1790639738]