[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-330131-105":59,"doc-detail-330131-en":135},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":128,"head_meta":130,"extra_data":132,"updated_unix":134},105,"en","the-feasibility-of-mr-elastography-with-transpelvic-vibration-for-localization-of-focal-prostate-lesion","The feasibility of MR elastography with transpelvic vibration for localization of focal prostate lesion","","The study evaluates the feasibility of transpelvic magnetic resonance elastography (MRE) for localizing focal prostate lesions without intracavitary actuators. Thirty-one patients underwent prostate MRE and had confirmed pathological diagnoses. A passive driver at the umbilicus and iliac crests produced shear-wave images for quantitative assessment of prostate cancer and benign prostatic hyperplasia (BPH). Cancer lesions showed higher mean shear stiffness than BPH (5.99 ± 1.46 vs. 4.67 ± 1.54 kPa), with excellent inter-reader agreement (ICC = 0.95).",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-feasibility-of-mr-elastography-with-transpelvic-vibration-for-localization-of-focal-prostate-lesion/330131/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-feasibility-of-mr-elastography-with-transpelvic-vibration-for-localization-of-focal-prostate-lesion/330131.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"What was the main aim of the study?","Question",{"text":113,"@type":114},"To assess the feasibility of prostate MRE using a transpelvic vibration approach without intracavitary actuators.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the MRE vibration delivered in this protocol?",{"text":118,"@type":114},"A passive driver was placed at the umbilicus and iliac crests to generate shear waves through transpelvic vibration.",{"name":120,"@type":111,"acceptedAnswer":121},"What quantitative results distinguished prostate cancer from BPH?",{"text":122,"@type":114},"Mean shear stiffness was significantly higher for cancer than for BPH (5.99 ± 1.46 kPa vs. 4.67 ± 1.54 kPa; p = 0.045).",{"name":124,"@type":111,"acceptedAnswer":125},"How consistent were readers when interpreting MRE?",{"text":126,"@type":114},"Inter-reader agreement for interpreting MRE was excellent, with an intraclass correlation coefficient (ICC) of 0.95.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},330131,1790101970,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","[www. nature.com/scientificreports](www. nature.com/scientificreports)  \nOPEN  \nThe feasibility of MR elastography with transpelvic vibration for localization of focal prostate lesion  \nHyo Jeong Lee1, Soo Buem Cho1*, Jeong Kyong Lee1, Jin Sil Kim1, Chang Hoon Oh1, Hyun Jin Kim1, Hana Yoon2, Hyun Kyu Ahn2, Myong Kim2, Yeok Gu Hwang3, Hye Young Kwon4 & Moon Jung Hwang5  \nWe aimed to evaluate the feasibility of MR elastography (MRE) using a transpelvic approach. Thirtyone patients who underwent prostate MRE and had a pathological diagnosis were included in this study. MRE was obtained using a passive driver placed at the umbilicus and iliac crests. The shear stiffness, clinical data, and conventional imaging findings of prostate cancer and benign prostatic hyperplasia (BPH) were compared. Inter-reader agreements were evaluated using the intraclass coefficient class (ICC). Prostate MRE was successfully performed for all patients (100% technical success rate) . Nineteen cancer and 10 BPH lesions were visualized on MRE. The mean shear stiffness of cancer was significantly higher than that of BPH (5.99 ± 1.46 kPa vs. 4.67 ± 1.54 kPa, p = 0.045) . One cancer was detected on MRE but not on conventional sequences. Six tiny cancer lesions were not visualized on MRE. The mean size of cancers that were not detected on MRE was smaller than that of cancers that were visible on MRE (0.8 ± 0.3 cm vs. 2.3 ± 1.8 cm, p = 0.001). The inter-reader agreement for interpreting MRE was excellent (ICC = 0.95) . Prostate MRE with transpelvic vibration is feasible without intracavitary actuators. Transpelvic prostate MRE is reliable for detecting focal lesions, including clinically significant prostate cancer and BPH.  \nMagnetic resonance elastography (MRE) is a phase contrast-based MRI technique that visualizes propagating mechanical waves and processes the data to develop quantitative images that represent intrinsic mechanical properties1. MRE is a non-invasive imaging modality that can be used to diagnose and manage diseases, such as cancer or fibrosis, with mechanical properties correlate well with tissue abnormalities. In MRE, a harmonically driven mechanical exciter generates shear waves, which are visualized and calculated to determine the shear modulus1,2.  \nThe clinical value of MRE was first demonstrated in the assessment of hepatic fibrosis3–5. Thereafter, MRE has been widely studied for the detection of abnormalities in the breast6, brain7, lungs8, and heart9. There has also been considerable interest in the utilization of MRE for the assessment of the prostate. Current MRE techniques have limitations in delivering a sufficient level of shear wave amplitude to the prostate, which is located in the deep pelvis, in a patient-friendly manner. Several methods of generating shear wave vibrations in the prostate, including transurethral, transrectal, and transperineal approaches, have been investigated10–12. However, these methods can cause discomfort to patients and require additional devices or equipment.  \nTherefore, the aim of this study was to investigate the feasibility of prostate MRE using transpelvic vibration without intracavitary actuators.  \nMaterial and methods  \nStudy population  \nThis retrospective single-center study was approved by the institutional review board of Ewha Womans University (IRB No. 2023-07-043-002), which waived the need for obtaining informed consent from the patients. All  \n1Department of Radiology, Ewha Womans University College of Medicine, Seoul, South Korea. 2Department of Urology, Ewha Womans University College of Medicine, Seoul, South Korea. 3Department of Orthopedic Surgery, Ewha Womans University College of Medicine, Seoul, South Korea. 4Department of Radiology, Chungnam National University College of Medicine, Daejeon, South Korea. 5GEHC, Seoul, Korea. * email: [sbcho@ewha.ac.kr](sbcho@ewha.ac.kr)  \n[www. nature.com/scientificreports/](www. nature.com/scientificreports/)  \nmethods were performed in accord","cbCaitlHBpvg3jVs","https://ap.wps.com/l/cbCaitlHBpvg3jVs","pdf",1532159,"English","# Study population\n## Imaging technique\n# Imaging analysis\n# Statistical evaluation","[{\"question\":\"What was the main aim of the study?\",\"answer\":\"To assess the feasibility of prostate MRE using a transpelvic vibration approach without intracavitary actuators.\"},{\"question\":\"How was the MRE vibration delivered in this protocol?\",\"answer\":\"A passive driver was placed at the umbilicus and iliac crests to generate shear waves through transpelvic vibration.\"},{\"question\":\"What quantitative results distinguished prostate cancer from BPH?\",\"answer\":\"Mean shear stiffness was significantly higher for cancer than for BPH (5.99 ± 1.46 kPa vs. 4.67 ± 1.54 kPa; p = 0.045).\"},{\"question\":\"How consistent were readers when interpreting MRE?\",\"answer\":\"Inter-reader agreement for interpreting MRE was excellent, with an intraclass correlation coefficient (ICC) of 0.95.\"}]","The feasibility of MR elastography with transpelvic vibration for localization of focal prostate lesion | PDF",1789987337,18]