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For children diagnosed with attention-deficit/hyperactivity disorder (ADHD), stimulant therapy may influence appetite and thereby alter body weight and growth trajectories. Yet real-world evidence on how such treatment affects BMI category assignment remains limited. This observational cohort study evaluated longitudinal changes in BMI classification after initiating stimulant therapy using data from Clalit Health Services, Israel.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-effect-of-adhd-stimulant-treatment-on-weight-categories-in-children-and-adolescents-read-online/461428/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-effect-of-adhd-stimulant-treatment-on-weight-categories-in-children-and-adolescents-read-online/461428.png","ImageObject",300,407,{"name":92,"@type":93},"Guten tag","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",17,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the study’s objective regarding ADHD stimulant therapy?","Question",{"text":113,"@type":114},"To evaluate how ADHD stimulant treatment affects transitions between BMI categories in children and adolescents.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were BMI categories defined in the study?",{"text":118,"@type":114},"BMI was grouped into normal weight, overweight, obesity, and severe obesity.",{"name":120,"@type":111,"acceptedAnswer":121},"What did the study find about BMI category transitions?",{"text":122,"@type":114},"Many children moved to a lower BMI category, while a notable minority experienced weight gain, indicating meaningful shifts during stimulant therapy.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},461428,1790794511,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":46,"preview_page_count":4},687212321768,"https://ap-avatar.wpscdn.com/avatar/a0010bdbe886d2fe77?x-image-process=image/resize,m_fixed,w_180,h_180&k=1789897067658708522","Article  \nThe Effect of ADHD Stimulant Treatment on Weight Categories in Children and Adolescents  \nShlomit Yaron 1, Ronen Arbel 2,3, Talish Razi 2 and Dan Nemet 2,4,5, *  \nAcademic Editor: Napoleon Waszkiewicz  \nReceived: 14 November 2025  \nRevised: 17 December 2025  \nAccepted: 18 December 2025  \nPublished: 21 December 2025  \nCopyright: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 Schneider Children’s Medical Center of Israel, P.O. Box 559, Petach Tikvah 4920235, Israel; [yshlomit@clalit.org.il](yshlomit@clalit.org.il)  \n2 Clalit Health Services, Community Medical Services Division, 101 Arlozorov Street, Tel Aviv 6209804, Israel  \n3 Maximizing Health Outcomes Lab, Sapir College, Sderot 7915600, Israel  \n4 Child Health and Sports Center, Department of Pediatrics, Meir Medical Center, 59 Tchernichovski Street, Kfar-Saba 44281, Israel  \n5 School of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel  \n* Correspondence: [dan.nemet@clalit.org.il](dan.nemet@clalit.org.il); Tel.: +972-9-7472134; Fax: +972-9-7471303  \nAbstract  \nObjective: Pediatric overweight and obesity represent a growing public health concern with significant long-term implications. In children diagnosed with attentiondeficit/hyperactivity disorder (ADHD), stimulant medications may alter appetite, potentially impacting body weight and growth patterns. However, real-world data on the effect of these treatments on body mass index (BMI) classification remains scarce. We aimed to evaluate the effect of ADHD stimulant therapy on transitions in the BMI categories among children. Study Design: We conducted a large-scale observational cohort study assessing longitudinal changes in BMI classification following the initiation of stimulant treatment, utilizing data from Clalit Health Services, Israel’s largest healthcare provider. BMI was categorized into four groups: normal weight, overweight, obesity, and severe obesity. Subgroup analysis was performed by sex and age groups: \u003C7 years; >7 \u003C13 years and >13 \u003C18 years. Results: At baseline, 26,930 children met the study inclusion criteria.  \n12,448 (46%) were classified as overweight or obese. Most children with normal weight at baseline maintained their BMI classification (90%) . 48% of children with overweight, 42% with obesity, and 29% with severe obesity transitioned to a lower BMI category. 39% of children with underweight transitioned to normal weight. Similar patterns in BMI category transitions were observed between sexes. Transition to a lower BMI category was more prevalent in the younger age group. Conclusions: Stimulant therapy for ADHD is associated with significant shifts in BMI classification among pediatric patients. While many children, especially younger with higher baseline BMI, experienced improvements in weight status, a notable minority exhibited weight gain. These findings underscore the importance of routine BMI monitoring and weight management strategies during ADHD treatment.  \nKeywords: attention-deficit hyperactivity disorder; medications; weight; growth  \n1. Introduction  \nAttention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in childhood, commonly managed with stimulant medications such as methylphenidate or amphetamines [1] . These medications are known to suppress appetite and may lead to reduced caloric intake, particularly during the initial stages of  \ntreatment. Consequently, weight loss is a documented side effect of stimulant therapy in children [2,3] .  \nPediatric obesity is another growing health concern worldwide. Despite intense efforts to maintain proper body weight, prevent weight gain, or promote weight loss, the incidence of obesity and its complications among children and adolescents is growing to epidemic proportions. Pediatric obe","cbCaia1CxOQ9ysRo","https://ap.wps.com/l/cbCaia1CxOQ9ysRo","pdf",196275,"English","# Abstract\n# Introduction\n# Methods\n# Results\n# Conclusions","[{\"question\":\"What was the study’s objective regarding ADHD stimulant therapy?\",\"answer\":\"To evaluate how ADHD stimulant treatment affects transitions between BMI categories in children and adolescents.\"},{\"question\":\"How were BMI categories defined in the study?\",\"answer\":\"BMI was grouped into normal weight, overweight, obesity, and severe obesity.\"},{\"question\":\"What did the study find about BMI category transitions?\",\"answer\":\"Many children moved to a lower BMI category, while a notable minority experienced weight gain, indicating meaningful shifts during stimulant therapy.\"}]","The Effect of ADHD Stimulant Treatment on Weight Categories in Children and Adolescents - read online | PDF",1790761585]