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The paper details preventive, restorative, and rehabilitative management strategies tailored to these risks, and outlines clinical considerations for preventing and treating treatment-related complications. It emphasizes the need for coordinated multidisciplinary care and highlights areas where evidence remains insufficient.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-dental-management-of-patients-irradiated-for-head-and-neck-cancer-clinical-open-verifiable-cpd-paper/384781/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-dental-management-of-patients-irradiated-for-head-and-neck-cancer-clinical-open-verifiable-cpd-paper/384781.png","ImageObject",300,407,{"name":92,"@type":93},"Ophelia","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why are dental complications common in head and neck cancer patients receiving radiotherapy?","Question",{"text":113,"@type":114},"Radiotherapy damages not only malignant cells but also vulnerable normal tissues in the oral cavity. This leads to characteristic syndromes such as xerostomia, mucositis, trismus, radiation caries, and osteoradionecrosis.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What is the role of the multidisciplinary team in managing irradiated patients?",{"text":118,"@type":114},"A multidisciplinary team is central to preventive, restorative, and rehabilitative care. 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Goh,*1 Nicholas Beech,1 Nigel R. Johnson1,2,3 and Martin Batstone1,4  \nKey points  \nPatients undergoing radiotherapy for head and neck cancers are prone to a range of dental complications, including mucositis, trismus, xerostomia, radiation caries and osteoradionecrosis.  \nThe multidisciplinary team plays a central role in the preventive, restorative and rehabilitative management of irradiated head and neck cancer patients.  \nFurther research is required to support decisions around pre-radiotherapy extractions, implant placement in irradiated bone, and the treatment and prevention of osteoradionecrosis.  \nAbstract  \nPatients undergoing radiotherapy for head and neck cancers are prone to a range of dental complications, including mucositis, trismus, xerostomia, radiation caries and osteoradionecrosis. Specific considerations include the preventive, restorative and rehabilitative management of such patients, and the prevention and treatment of complications. This article aims to highlight the current understanding and management of dental needs for patients who have had or will undergo radiotherapy.  \nIntroduction  \nRadiotherapy for head and neck cancers utilises ionising radiation to damage the genetic material of vulnerable malignant cells and cause cell death. Adverse effects arise from the same mechanisms damaging normal cells, especially those which are rapidly dividing or less capable of repair. In the oral cavity, these can be cells of the mucous membranes, underlying soft tissue, salivary glands, teeth, periosteum, bone and vasculature. This results in specific radiation syndromes: xerostomia from salivary gland injury; mucositis from epithelial damage; trismus from collagen structure changes; radiation caries from pathological alterations in tooth structure and normal flora; and osteoradionecrosis (ORN) from reduced bone healing capacity.  \n1Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia; 2School of Dentistry, University of Queensland, Brisbane, Queensland, Australia; 3Oral and Maxillofacial Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia; 4Oral and Maxillofacial Department, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia.  \n*Correspondence to: Elizabeth Z. Goh Email address: [elizabeth.goh@uq. net.au](elizabeth.goh@uq. net.au)  \nRefereed Paper.  \nSubmitted 10 November 2022  \nRevised 10 February 2023  \nAccepted 3 March 2023  \n[https://doi.org/10.1038/s41415-023-5864-z](https://doi.org/10.1038/s41415-023-5864-z)  \nManagement of oral health is paramount for head and neck cancer patients, as dental complications are common . Important considerations include specific preventive, restorative and rehabilitative management, and the prevention and treatment of complications. Since our first article,1 the past decade has seen increasing use of dental implants and landmark ORN clinical trials. In this article, we aim to provide an update on the current management of dental needs for patients who have had or will undergo radiotherapy.  \nPre-radiotherapy  \nDental assessment  \nA multidisciplinary team (MDT) approach to managing head and neck cancer patients is considered best practice.2 Given the oral implications of the disease and its treatment, the MDT should include dental practitioners with expertise in the preventive, restorative and rehabilitative management of these patients.2 MDT variations can be expected internationally.2 For example, in the UK, both pre-treatment assessment and post-surgical rehabilitation are performed by specialist restorative dentists in the MDT, while in Australia, this is commonly performed by experienced general dentists and specialist prosthodontists. While abiding by local standard care pathways is important, the principles of care remain the same.  \nIdeally, every patient r","cbCaimA9dWEBK5In","https://ap.wps.com/l/cbCaimA9dWEBK5In","pdf",341481,"English","# Key points\n## Dental complications in irradiated patients\n## Role of the multidisciplinary team\n## Research needs for clinical decisions\n# Abstract\n# Introduction\n## Mechanisms and oral radiation syndromes\n# Pre-radiotherapy\n## Dental assessment\n## Risk factors and clinical planning\n# Prevention and restorations","[{\"question\":\"Why are dental complications common in head and neck cancer patients receiving radiotherapy?\",\"answer\":\"Radiotherapy damages not only malignant cells but also vulnerable normal tissues in the oral cavity. This leads to characteristic syndromes such as xerostomia, mucositis, trismus, radiation caries, and osteoradionecrosis.\"},{\"question\":\"What is the role of the multidisciplinary team in managing irradiated patients?\",\"answer\":\"A multidisciplinary team is central to preventive, restorative, and rehabilitative care. It supports coordinated decision-making to manage oral health needs and complications.\"},{\"question\":\"What key decisions require further research before radiotherapy?\",\"answer\":\"Further research is needed to guide decisions such as pre-radiotherapy extractions, implant placement in irradiated bone, and approaches for treatment and prevention of osteoradionecrosis.\"}]","The dental management of patients irradiated for head and neck cancer - Clinical Open - Verifiable CPD paper | PDF",1790264977,13]