[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-384051-105":59,"doc-detail-384051-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","the-current-trend-of-radiation-therapy-for-patients-with-localized-prostate-cancer-review","The Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer - Review","","A recent approach to radiotherapy for localized prostate cancer focuses on delivering high radiation doses to the prostate while limiting damage to surrounding organs. Image-guided radiotherapy supports dose escalation through advanced imaging and provides a feasible pathway to higher target accuracy. Radioactive particle–based strategies and prostate brachytherapy are discussed as additional methods for safe, high-dose treatment. Spacers, especially hydrogel, are highlighted to protect adjacent organs such as the rectum from excessive exposure.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-current-trend-of-radiation-therapy-for-patients-with-localized-prostate-cancer-review/384051/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-current-trend-of-radiation-therapy-for-patients-with-localized-prostate-cancer-review/384051.png","ImageObject",300,407,{"name":92,"@type":93},"Cart","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-25","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main goal of current radiotherapy trends for localized prostate cancer?","Question",{"text":112,"@type":113},"Current approaches aim to increase the radiation dose to the prostate while minimizing exposure and side effects in nearby organs, including the rectum, bladder, and urethra.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does image-guided radiotherapy help treatment planning?",{"text":117,"@type":113},"It uses advanced imaging techniques to improve target precision, making dose escalation feasible while reducing radiation to adjacent tissues.",{"name":119,"@type":110,"acceptedAnswer":120},"Why are spacers important in radiotherapy?",{"text":121,"@type":113},"Spacers protect organs at risk—particularly the rectum—from excessive radiation exposure during treatment.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},384051,1790893216,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":56,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},18829141979164,"https://eur-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Review  \nThe Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer  \nKazuyuki Numakura 1, *, Mizuki Kobayashi 1, Yumina Muto 1, Hiromi Sato 1, Yuya Sekine 1, Ryuta Sobu 1, Yu Aoyama 1, Yoshiko Takahashi 1, Syuhei Okada 1, Hajime Sasagawa 1, Shintaro Narita 1, Satoshi Kumagai 2, Yuki Wada 2, Naoko Mori 2 and Tomonori Habuchi 1  \nCitation: Numakura, K.; Kobayashi, M.; Muto, Y.; Sato, H.; Sekine, Y.; Sobu, R.; Aoyama, Y.; Takahashi, Y.; Okada, S.; Sasagawa, H.; et al. The Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer. Curr. Oncol. 2023, 30, 8092–8110. [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)curroncol30090587  \nReceived: 23 June 2023  \nRevised: 22 August 2023  \nAccepted: 28 August 2023  \nPublished: 1 September 2023  \nCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Department of Urology, Akita University Graduate School of Medicine, Akita 010-8543, Japan;  \n[qqc83rkd@piano.ocn.ne.jp](qqc83rkd@piano.ocn.ne.jp) (M.K.); [yumina.muto.0601@gmail.com](yumina.muto.0601@gmail.com) (Y.M.); [hiromisato2002@yahoo.co.jp](hiromisato2002@yahoo.co.jp) (H.S.);  \n[backup.sekine.bs@gmail.com](backup.sekine.bs@gmail.com) (Y.S.); [sobusan.sobusan.com@gmail.com](sobusan.sobusan.com@gmail.com) (R.S.);  \n[joseph.aoyama@gmail.com](joseph.aoyama@gmail.com) (Y.A.); [yopico.t@gmail.com](yopico.t@gmail.com) (Y.T.); [sh.ok.gn10.phy2@gmail.com](sh.ok.gn10.phy2@gmail.com) (S.O.);  \n[sasahazi.820@gmail.com](sasahazi.820@gmail.com) (H.S.); [naritashintaro@gmail.com](naritashintaro@gmail.com) (S.N.); [thabuchi@gmail.com](thabuchi@gmail.com) (T.H.)  \n2 Department of Radiology, Akita University Graduate School of Medicine, Akita 010-8543, Japan; [skuma@med.akita-u.ac.jp](skuma@med.akita-u.ac.jp) (S.K.); [ywada@med.akita-u.ac.jp](ywada@med.akita-u.ac.jp) (Y.W.); [nmori@med.akita-u.ac.jp](nmori@med.akita-u.ac.jp) (N.M.)  \n* [Correspondence: nqf38647@nifty.com](Correspondence: nqf38647@nifty.com); Tel.: +81-18-884-6460  \nAbstract: A recent approach to radiotherapy for prostate cancer is the administration of high doses of radiation to the prostate while minimizing the risk of side effects. Thus, image-guided radiotherapy utilizes advanced imaging techniques and is a feasible strategy for increasing the radiation dose. New radioactive particles are another approach to achieving high doses and safe procedures. Prostate brachytherapy is currently considered as a combination therapy. Spacers are useful to protect adjacent organs, specifically the rectum, from excessive radiation exposure.  \nKeywords: prostate cancer; radiation therapy; intensity-modulated radiation therapy; image-guided radiation therapy; volumetric modulated arc therapy; stereotactic body radiation therapy; brachytherapy; metastasis direct therapy; hydrogel spacer  \n1. Introduction  \nThe current trend in radiotherapy for patients with localized prostate cancer is characterized by the implementation of high-dose irradiation using advanced techniques to enable more precise targeting of the tumor while minimizing radiation exposure to adjacent organs, including the rectum, bladder, and urethra [1] . Radiotherapy is a conventional treatment option for localized prostate cancer, and management approaches vary depending on the patient's National Comprehensive Cancer Network (NCCN) risk [2,3] .  \nAccording to previous trials, radical prostatectomy and external beam radiation therapy (EBRT) are similarly effective in terms of overall survival (OS), disease-specific survival (DSS), biochemical relapse-free survival (bRFS), and quality of life (QOL) for localized prostate cancer [4,5] .  \nRadiotherapy may also be","cbCaihYY75vOhoxi","https://ap.wps.com/l/cbCaihYY75vOhoxi","pdf",477012,"English","# Introduction\n# Radiotherapy for Each Risk of Localized Prostate Cancer\n## Low-Risk Prostate Cancer\n## Intermediate-Risk Prostate Cancer","[{\"question\":\"What is the main goal of current radiotherapy trends for localized prostate cancer?\",\"answer\":\"Current approaches aim to increase the radiation dose to the prostate while minimizing exposure and side effects in nearby organs, including the rectum, bladder, and urethra.\"},{\"question\":\"How does image-guided radiotherapy help treatment planning?\",\"answer\":\"It uses advanced imaging techniques to improve target precision, making dose escalation feasible while reducing radiation to adjacent tissues.\"},{\"question\":\"Why are spacers important in radiotherapy?\",\"answer\":\"Spacers protect organs at risk—particularly the rectum—from excessive radiation exposure during treatment.\"}]","The Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer - Review | PDF",1790261004,48]