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Clinical, functional, and structural imaging evidence supports cerebellar involvement in these conditions. This narrative review discusses the cerebellum’s role by consolidating evidence on affected cerebellar regions and their connections, and by outlining implications across cognitive, emotional, and behavioral domains.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-cerebellum-and-psychiatric-disorders-unraveling-its-role-in-mental-health/435876/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-cerebellum-and-psychiatric-disorders-unraveling-its-role-in-mental-health/435876.png","ImageObject",300,407,{"name":92,"@type":93},"Himbo","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Which psychiatric disorders are associated with cerebellar abnormalities?","Question",{"text":113,"@type":114},"The article highlights associations with schizophrenia, bipolar disorder, depression, anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD).","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What types of evidence support the cerebellum’s involvement in mental health?",{"text":118,"@type":114},"The review states that clinical, functional, and structural imaging studies support involvement of the cerebellum across these conditions.",{"name":120,"@type":111,"acceptedAnswer":121},"What is the purpose of this narrative review?",{"text":122,"@type":114},"It aims to comprehensively discuss and highlight the cerebellum’s role in psychiatric disorders by gathering evidence about affected cerebellar locations, connections, and implications for cognitive, emotional, and behavioral domains.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},435876,1790716388,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":46,"preview_page_count":4},687197100911,"https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697","Article published online: 2025-08-31  \nReview Article 1  \nThe cerebellum and psychiatric disorders: unraveling its role in mental health  \nPedro Braga-Neto 1,2 Maria Wanessa Barbosa dos Santos 1 Stephanie Suzanne de Oliveira Scott 1 Renato Puppi Munhoz3 Luiz Eduardo Novis4 José Luiz Pedroso4  \nOrlando Graziani Povoas Barsottini4  \n1 Universidade Federal do Ceará, Faculdade de Medicina, Departamento de Clínica Médica, Seção de Neurologia, Fortaleza CE, Brazil.  \n2 Universidade do Estado do Ceará, Centro de Ciências da Saúde, Fortaleza CE, Brazil.  \n3 University Health Network, Toronto Western Hospital, Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson ’s Disease, Toronto ON, Canada.  \n4 Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, Unidade de Ataxia, São Paulo SP, Brazil.  \nArq. Neuro-Psiquiatr. 2025;83(8):s00451810408 .  \nAddress for correspondence Orlando Graziani Povoas Barsottini (email: [orlandobarsottini@gmail.com](orlandobarsottini@gmail.com))  \nAbstract  \nKeywords  \n► Cerebellum  \n► Mental Disorders  \n► Mental Health  \nSeveral studies describe a strong association between structural and functional abnormalities of the cerebellum and psychiatric disorders. It is possible to find investigations especially in cases of schizophrenia, bipolar disorder, depression, anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD) . The involvement of the cerebellum in these conditions is also supported by clinical, functional, and structural imaging studies. The present narrative review aims to discuss and highlight the role of the cerebellum in these disorders, gathering evidence on the possible locations and connections of the affected cerebellar areas and their implications in the cognitive, emotional, and behavioral domains.  \nINTRODUCTION  \nThe cerebellum is traditionally known for its role in motorrelated functions. However, increasing evidence suggests that the cerebellum plays a much broader role, including the modulation of social and affective behaviors. Current research indicates the cerebellum’sinfluence on subcortical regions, as well as on cortical processes that extend beyond the motor domain. 1,2 Notably, several studies have found strong associations between structural and functional abnormalities of the cerebellum and various psychiatric disorders, particularly schizophrenia, bipolar disorder, depression, anxiety disorders, attention-deficit hyperactivity disorder (ADHD), and autism  \nreceived  \nMarch 6, 2025  \nreceived in its final form May 5, 2025  \naccepted May 19, 2025  \nDOI [https://doi.org/](https://doi.org/)[ ](https://doi.org/)10.1055/s-0045-1810408 . ISSN 0004-282X.  \nEditor-in-Chief: Hélio A. G. Teive.  \nAssociate Editor: Antonio Lucio Teixeira.  \nspectrum disorder (ASD). The involvement of the cerebellum in these conditions is further supported by clinical, functional and structural imaging studies.3  \nThe present narrative review aims to comprehensively discuss and highlight the role of the cerebellum in various psychiatric disorders, in addition to endorsing the need for the development of studies that deepen the understanding of this complex and functionally-diverse structure. ►Table 1 systematically gathers the main anatomical regions of the cerebellum associated with different psychiatric disorders. The selection of these areas is based on previous studies focused on new discoveries about cerebellar functioning. ►Table 1 aims to  \n© 2025 . The Author(s) .  \nThis is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit ([https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/))  \nThieme Revinter Publicações Ltda. , Rua Rego Freitas, 175, loja 1, República, São Pa","cbCaigzUYtPYDHiE","https://ap.wps.com/l/cbCaigzUYtPYDHiE","pdf",644168,"English","# Introduction\n# The role of the cerebellum in mental health: anatomical and physiological bases\n## Table 1: Cerebellum’s anatomical areas associated with psychiatric disorders\n## Figure 1: Neural communication pathways between the cerebellum and brain structures","[{\"question\":\"Which psychiatric disorders are associated with cerebellar abnormalities?\",\"answer\":\"The article highlights associations with schizophrenia, bipolar disorder, depression, anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD).\"},{\"question\":\"What types of evidence support the cerebellum’s involvement in mental health?\",\"answer\":\"The review states that clinical, functional, and structural imaging studies support involvement of the cerebellum across these conditions.\"},{\"question\":\"What is the purpose of this narrative review?\",\"answer\":\"It aims to comprehensively discuss and highlight the cerebellum’s role in psychiatric disorders by gathering evidence about affected cerebellar locations, connections, and implications for cognitive, emotional, and behavioral domains.\"}]","The cerebellum and psychiatric disorders: unraveling its role in mental health | PDF",1790675763]