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The development of anti-tumor materials provides new modalities for cancer diagnosis and treatment. This review summarizes research progress and clinical applications of anti-tumor materials by introducing cancer etiology, pathogenesis, and key challenges, then classifying anti-tumor materials and analyzing their mechanisms. It further details advances and clinical use, including tumor-cell targeting and therapeutic instruments, and closes with future perspectives and open challenges.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/the-advancements-and-targeted-therapy-prospective-developments-in-anti-tumor-read-online-free/332334/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/the-advancements-and-targeted-therapy-prospective-developments-in-anti-tumor-read-online-free/332334.png","ImageObject",300,407,{"name":92,"@type":93},"Oliver","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What does the review focus on regarding cancer treatment?","Question",{"text":112,"@type":113},"It focuses on the advancements and prospective developments of anti-tumor materials used for cancer diagnosis and treatment, emphasizing targeted therapy approaches.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does the review structure the discussion of anti-tumor materials?",{"text":117,"@type":113},"It introduces cancer etiology and challenges first, then classifies anti-tumor materials and discusses their mechanisms, followed by research advances and clinical applications.",{"name":119,"@type":110,"acceptedAnswer":120},"What advantages and challenges of anti-tumor materials are highlighted?",{"text":121,"@type":113},"The review highlights high specificity, low side effects, and high efficacy, while noting that challenges remain, including ongoing issues in the field despite progress.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332334,1791272415,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},8796095461610,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Neoplasia 56 (2024) 101024  \nContents lists available at ScienceDirect  \nNeoplasia  \njournal [homepage:](homepage: www.elsevier.com/locate/neo)[ www.elsevier.com/locate/neo](homepage: www.elsevier.com/locate/neo)  \n| Review Article The advancements and targeted therapy |  | prospective developments in anti-tumor |  | |\n| --- | --- | --- | --- | --- |\n| Guorui Lenga,1, Baorong Duan b,1, Junjie Liuc, Song Lia, Wenwen Zhao a, Shanshan Wang d, Guige Houd,*, Jiale Qu d,e,*\u003Cbr>a School of Special Education and Rehabilitation, Binzhou Medical University, Yantai 264003, China\u003Cbr>b Research Center for Leather and Protein of College of Chemistry & Chemical Engineering, Yantai University, Yantai 264005, China c Department of Physics, Binzhou Medical University, Yantai 264003, China\u003Cbr>d School of Pharmacy, Binzhou Medical University, Yantai 264003, China\u003Cbr>e Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Provincial Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, China |  |  |  |  |\n| A R T I C L E I N F O |  |  | A B S T R A C T |  |\n| Keywords:\u003Cbr>Anti-tumor materials Targeted therapy Tumor microenvironment Immunotherapy Challenge and prospect |  |  | Cancer poses a major threat to human health worldwide. The development of anti-tumor materials provides new modalities for cancer diagnosis and treatment. In this review, we comprehensively summarize the research progress and clinical applications of anti-tumor materials. First, we introduce the etiology and pathogenesis of cancer, and the significance and challenges of anti-tumor materials research. Then, we classify anti-tumor materials and discuss their mechanisms of action. After that, we elaborate the research advances and clinical applications of anti-tumor materials, including those targeting tumor cells and therapeutic instruments. Finally, we discuss the future perspectives and challenges in the field of anti-tumor materials. This review aims to provide an overview of the current status of anti-tumor materials research and application, and to offer insights into future directions in this rapidly evolving field, which holds promise for more precise, efficient and customized treatment of cancer. |  |\n\nIntroduction  \nCancer and pathogenesis  \nCancer, posing a formidable threat to human health and life, is a major cause of mortality worldwide [1,2]. The World Health Organization predicts over 20 million novel cancer cases will emerge annually by 2030 [3]. Cancer is a heterogenous disease formed through a series of complex biological processes, including DNA mutations and epigenetic modifications in cells, engendered by multiple pathogenic factors. Its pathogenesis involves numerous influencing factors intracellularly and extracellularly, encompassing genetic mutations, environmental factors, lifestyles, dietary habits, etc [4,5]. These factors, individually or in combination, lead to aberrations in cellular signal transduction and disrupt the equilibrium between cellular proliferation and apoptosis, thereby resulting in the inception and progression of tumors. The etiology of cancer is multifactorial, multi-staged and polygenic, rendering  \nthe pathogenesis of cancer remarkably complex, necessitating the comprehensive consideration of diverse factors.  \nIn light of the intricate etiology and pathophysiology of cancer, developing efficacious anti-tumor therapeutic modalities possesses pronounced clinical value. In this aspect, anti-tumor materials have garnered substantial attention owing to their potent biocompatibility, drug release modulation, targeting capabilities, etc. The research and application of anti-tumor materials are of pronounced clinical significance, capable of providing more efficacious approaches and modalities for cancer therapies, holding meaningful implications for the treatment and prevention of cancer.  \nSignifica","cbCaissbRRfhWVnZ","https://ap.wps.com/l/cbCaissbRRfhWVnZ","pdf",13117882,15,"English","# Introduction\n## Cancer and pathogenesis\n## Significance of investigating anti-tumor materials\n# Review Article Overview\n## Research progress and clinical applications\n## Classification and mechanisms of action\n## Future perspectives and challenges","[{\"question\":\"What does the review focus on regarding cancer treatment?\",\"answer\":\"It focuses on the advancements and prospective developments of anti-tumor materials used for cancer diagnosis and treatment, emphasizing targeted therapy approaches.\"},{\"question\":\"How does the review structure the discussion of anti-tumor materials?\",\"answer\":\"It introduces cancer etiology and challenges first, then classifies anti-tumor materials and discusses their mechanisms, followed by research advances and clinical applications.\"},{\"question\":\"What advantages and challenges of anti-tumor materials are highlighted?\",\"answer\":\"The review highlights high specificity, low side effects, and high efficacy, while noting that challenges remain, including ongoing issues in the field despite progress.\"}]","The advancements and targeted therapy - prospective developments in anti-tumor - read online free | PDF",1789997758,38]