[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-357299-105":3,"doc-detail-357299-en":81,"detail-sidebar-cat-0-en-105":99},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","teaching-six-blink-features-reduces-general-endoscopist-cancer-miss-rate-in-image-based-assessment-of-large-colorectal-polyps","Teaching Six “blink” features reduces general endoscopist cancer miss rate in image-based assessment of large colorectal polyps","","Accurate cancer detection in large non-pedunculated colorectal polyps remains difficult for general endoscopists. A prospective interventional study tested whether training six gross morphological “blink” features could improve image-based cancer identification. General endoscopists evaluated 20 LNPCP images before and after a 2-minute educational video. The cancer miss rate fell four-fold, while false alarms rose less than two-fold. Predictors included spontaneous bleeding, extra redness, and depression.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/teaching-six-blink-features-reduces-general-endoscopist-cancer-miss-rate-in-image-based-assessment-of-large-colorectal-polyps/357299/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/teaching-six-blink-features-reduces-general-endoscopist-cancer-miss-rate-in-image-based-assessment-of-large-colorectal-polyps/357299.png","ImageObject",300,407,{"name":42,"@type":43},"Kurz","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-03","2026-09-23",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",10,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What was the purpose of teaching the six “blink” features?","Question",{"text":63,"@type":64},"To determine whether training six gross morphological “blink” features could improve accuracy of cancer detection in image-based assessment of large non-pedunculated colorectal polyps.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was the study designed and what did participants do?",{"text":68,"@type":64},"A prospective interventional study assessed general endoscopists evaluating 20 LNPCP images before and after a 2-minute educational video introducing the six blink features.",{"name":70,"@type":61,"acceptedAnswer":71},"Which blink features were identified as independent predictors of cancer?",{"text":72,"@type":64},"Spontaneous bleeding, extra redness, and depression were independent predictors of cancer among general endoscopists in multivariable analysis.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},357299,1790929940,{"code":4,"msg":82,"data":83},"success",{"doc_id":79,"user_id":84,"nickname":42,"user_avatar":85,"doc_module":4,"category_id":86,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":87,"file_id":88,"file_url":89,"file_type":90,"file_size":91,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":92,"language":93,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":94,"faqs":95,"seo_title":96,"seo_description":12,"update_tm":97,"read_time":98},2336478945635,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8",7,"Accepted Manuscript online: 2026-05-10 Article published online: 2026-05-29  \nOriginal article  \nTeaching Six “blink” features reduces general endoscopist cancer miss rate in image-based assessment  \nof large colorectal polyps  \nGRAPHICAL ABSTRACT  \nAuthors  \nLynn K. Debels1,2 , Tamas Tornai3,4, John T. Anderson5 , Maria E. Argenziano2,3,6, Anne Hoorens7, Vikash G. Lala8,9 , Pieter Jan Poortmans10,2 , Sander Smeets2,3 , Roland Valori5, Lobke Desomer2,11 , David J. Tate2,12   \nInstitutions  \n1 Department of Gastroenterology and Hepatology, University Hospital Brussels, Anderlecht, Brussels, Belgium  \n2 Medicine and Health Sciences, Ghent University Faculty of Medicine and Health Sciences, Ghent, Flanders, Belgium  \n3 Department of Gastroenterology and Hepatology, University Hospital Ghent, Ghent, Flanders, Belgium  \n4 Institute of Pancreatic Diseases, Semmelweis University of Medicine, Budapest, Budapest, Hungary  \n5 Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, England, United Kingdom of Great Britain and Northern Ireland  \n6 Università Politecnica delle Marche, Ancona, Marche, Italy  \n7 Anatomopathology, University Hospital Ghent, Ghent, Flanders, Belgium  \n8 Department of Gastroenterology & Hepatology, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, GP, South Africa  \n9 Department of Gastroenterology and Hepatology, Wits University Donald Gordon Medical Centre, Parkstown, South Africa  \n10 Gastroenterology and Hepatology, UZ Brussel, Brussels, Belgium  \n11 Gastroenterology, AZ Delta, Roeselare, Belgium  \n12 Department of Gastroenterology and Hepatology, University Hospital Ghent, Gent, Oost-Vlaanderen, Belgium  \nKey words  \nEndoscopy Lower GI Tract, Polyps / adenomas / ... , Diagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE...), Quality and logistical aspects, Training, Colorectal cancer, Endoscopic resection (polypectomy, ESD, EMRc, ...)  \nreceived 21.11.2025  \naccepted after revision 1.5.2026 accepted manuscript online 10.5.2026  \nDebels Lynn K et al. Teaching Six \"blink\"… Endosc Int Open 2026; 14: a28684812 | © 2026. The Author(s) . E1  \nBibliography  \nEndosc Int Open 2026; 14: a28684812 DOI 10.1055/a-2868-4812  \nISSN 2364-3722  \n© 2026. The Author(s) .  \nThis is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited.  \n([https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/))  \nGeorg Thieme Verlag KG, Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany  \nCorresponding author  \nDavid J. Tate, MBBS MRCP (UK), MRCP (Gastro), Ghent University Faculty of Medicine and Health Sciences, Medicine and Health Sciences, Ghent, Flanders, Belgium [djtate@gmail.com](djtate@gmail.com)  \n Supplementary Material is available at [https://doi.org/10.1055/a-2868-4812](https://doi.org/10.1055/a-2868-4812)  \nABSTRACT  \nBackground and study aims Accurate cancer detection in large non-pedunculated colorectal polyps (LNPCPs) remains challenging for general endoscopists. We evaluated whether teaching six gross morphological \"blink\" features could improve accuracy of cancer detection.  \nMethods This prospective interventional study assessed general endoscopists evaluating 20 LNPCP images (7 with histologically confirmed submucosal invasive cancer includ-  \ning four deep invasions ≥ 1000 µm, 13 benign) . Participants assessed images before and after a 2-minute educational video introducing six blink features: spontaneous bleeding, depression, fold deformation, extra redness, ulceration, and chicken-skin mucosa. Primary outcome was change in miss-rate for cancer detection. Generalized linear mixed models accounted for clustering within raters and polyps. Results The 165 participants included gastroenterology consultants (63.6%), trainees (21.2%), students (1.8%) and colorectal surgeons (13.3%) with med","cbCaid36V0gbolpi","https://ap.wps.com/l/cbCaid36V0gbolpi","pdf",3654432,11,"English","# Abstract\n## Background and study aims\n## Methods\n## Results\n## Conclusions\n# Introduction","[{\"question\":\"What was the purpose of teaching the six “blink” features?\",\"answer\":\"To determine whether training six gross morphological “blink” features could improve accuracy of cancer detection in image-based assessment of large non-pedunculated colorectal polyps.\"},{\"question\":\"How was the study designed and what did participants do?\",\"answer\":\"A prospective interventional study assessed general endoscopists evaluating 20 LNPCP images before and after a 2-minute educational video introducing the six blink features.\"},{\"question\":\"Which blink features were identified as independent predictors of cancer?\",\"answer\":\"Spontaneous bleeding, extra redness, and depression were independent predictors of cancer among general endoscopists in multivariable analysis.\"}]","Teaching Six “blink” features reduces general endoscopist cancer miss rate in image-based assessment of large colorectal polyps | PDF",1790129563,28,{"code":4,"msg":82,"data":100},[101,105,109,113,118,123,126,131,136,139,142],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":110,"show_sort_weight":111,"slug":112},"Exam",70,"exam",{"id":114,"doc_module":4,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},5,"Comic",60,"comic",{"id":119,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},6,"Technology",50,"technology",{"id":86,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":124,"slug":125},40,"healthcare",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":129,"slug":130},8,"Research & Report",30,"research-report",{"id":132,"doc_module":4,"doc_module_name":25,"category_name":133,"show_sort_weight":134,"slug":135},9,"Religion & Spirituality",20,"religion-spirituality",{"id":134,"doc_module":4,"doc_module_name":25,"category_name":137,"show_sort_weight":134,"slug":138},"World Cup","world-cup",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":140,"show_sort_weight":55,"slug":141},"Lifestyle","lifestyle",{"id":143,"doc_module":4,"doc_module_name":25,"category_name":144,"show_sort_weight":114,"slug":145},19,"General","general"]