[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-399891-105":59,"doc-detail-399891-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","tay-sachs-disease-positive-carrier-screening-result-information-sheet","Tay-Sachs Disease - Positive Carrier Screening Result - Information Sheet","","Information sheet explaining what it means to be a Tay-Sachs (TS) carrier after receiving a positive carrier screening result. It clarifies that carrier status does not affect health and that TS develops only when both parents carry nonworking copies of the TS gene. Guidance covers partner testing, prenatal diagnostic options, and the chances of affected outcomes. It also describes TS as an inherited brain disease, typical progression in affected babies, current lack of cure, and limits of screening.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/tay-sachs-disease-positive-carrier-screening-result-information-sheet/399891/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/tay-sachs-disease-positive-carrier-screening-result-information-sheet/399891.png","ImageObject",300,407,{"name":92,"@type":93},"mieayamfan","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-27",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Does being a Tay-Sachs (TS) carrier affect your health?","Question",{"text":112,"@type":113},"No. Being a carrier does not affect your health. One copy of the Tay-Sachs gene does not work properly, but carriers have a second working copy.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Why is partner testing recommended after a positive TS carrier screening result?",{"text":117,"@type":113},"Partner testing helps determine the chance that a baby could have TS. Both parents must be TS carriers to be at risk for having a baby with TS.",{"name":119,"@type":110,"acceptedAnswer":120},"What diagnostic options are available if both parents are TS carriers during pregnancy?",{"text":121,"@type":113},"Prenatal testing can diagnose TS, including procedures such as amniocentesis or CVS. Results can help parents decide whether to continue the pregnancy, and families can also test after birth.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},399891,1790776739,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24,"preview_page_count":4},962090893677,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","INFORMATION SHEET  \nTay-Sachs Disease  \nPositive Carrier Screening Result  \nYou have recently learned that you are a Tay-Sachs (TS) carrier. Here is important information about being a TS carrier.  \nBeing a carrier does not affect your health. Everyone carries genes that do not work. Being a TS carrier means that one copy of the Tay-Sachs gene does not work properly. Carriers have a second copy of the Tay-Sachs gene that works normally. TS carriers do not develop Tay-Sachs disease. In fact, one of your parents is probably a TS carrier just like you. If you have brothers or sisters, they could also be carriers.  \nIf you are pregnant, the next step is to test your partner. Both parents must be TS carriers tobe at risk for a baby with TS. If one parent has a negative (normal) test result, the chance that a baby will have Tay-Sachs disease is very small. Testing can be done at any Kaiser Permanente laboratory. A genetic counselor will let you know how to arrange testing.  \nWhy test your partner?  \n• You want to know the chance that your baby could have TS.  \n• You want to be prepared if your baby is found to be at risk for TS.  \n• You might consider testing the baby for TS during pregnancy.  \nWhy would you not test your partner?  \n• You do not want to learn about a risk for TS during pregnancy.  \n• The result would not change anything you do during pregnancy.  \nWhat happens if my partner is a TS carrier?  \nWhen both parents are TS carriers, there is a 1 in 4 (25%) chance for a baby to develop Tay-Sachs disease. There is also a 3 in 4 (75%) chance that a baby will not have TS. If your partner is a TS carrier, you will be offered prenatal testing to find out if your baby could have Tay-Sachs. A procedure such as amniocentesis or CVS is able to diagnose TS during pregnancy. This test allows parents to decide whether or not to continue the pregnancy. You could also choose to wait until after birth to test your baby.  \nWhat is Tay-Sachs disease?  \nTay-Sachs is an inherited disease that affects the brain. A person with TS does not make enough of an enzyme called hexosaminidase A (HexA) . This enzyme normally breaks down fatty waste proteins in the brain. When there is not enough HexA, those waste proteins build up and damage the brain’s nerve cells, affecting vision, movement, hearing, and learning.  \nBabies with TS appear normal at birth, but development starts to slow by six months. By two years of age most children with TS have seizures and begin to lose motor skills and mental functions. TS usually leads to death before age five.  \nThere is no cure for Tay-Sachs at this time. Treatment can help with some symptoms but does not slow the disease. Research is being done to find new ways to treat TS.  \n\n| |\n| --- |\n| Tay-Sachs Carrier Screening\u003Cbr>Anyone can be a TS carrier, even if there is no history of TS in the family. The chance to be a TS carrier is highest for a person with Ashkenazi Jewish ancestry. For this reason, carrier screening for TS is routinely offered only when someone has Jewish ancestry. Carrier screening detects 98% of carriers in this population. |\n| \u003Cbr>\u003Cbr>Approximate carrier rates by ancestry or ethnic background:\u003Cbr>• Jewish: 1 in 25 (4%)\u003Cbr>• Non-Jewish 1 in 250 |\n| The chance could be higher if there is any history of TS in the family. Before having carrier screening, it is important to let your provider know if someone in the family had TS or is a TS carrier. Special testing may be offered.\u003Cbr>Limits of carrier screening:\u003Cbr>-A small number of carriers have changes in the TS gene that cannot be found by routine testing. This can lead to an apparently normal result in someone who really is a carrier. |\n\nNewborn Testing for Tay-Sachs  \nTesting can be requested soon after birth for babies who are at risk to develop TS. An early diagnosis can allow medical care to start as soon as possible. Tay-Sachs is not part of routine newborn screening in California at this time.  \nThis information is not intended to diagnos","cbCaicrpa0ximvRi","https://ap.wps.com/l/cbCaicrpa0ximvRi","pdf",175891,"English","# Tay-Sachs Disease - Positive Carrier Screening Result\n## What It Means to Be a TS Carrier\n## Next Step: Testing Your Partner\n## Why Test (or Not Test) Your Partner\n## If Both Parents Are TS Carriers\n## What Is Tay-Sachs Disease?\n## Carrier Screening Details\n## Limits of Carrier Screening\n## Newborn Testing for Tay-Sachs","[{\"question\":\"Does being a Tay-Sachs (TS) carrier affect your health?\",\"answer\":\"No. Being a carrier does not affect your health. One copy of the Tay-Sachs gene does not work properly, but carriers have a second working copy.\"},{\"question\":\"Why is partner testing recommended after a positive TS carrier screening result?\",\"answer\":\"Partner testing helps determine the chance that a baby could have TS. Both parents must be TS carriers to be at risk for having a baby with TS.\"},{\"question\":\"What diagnostic options are available if both parents are TS carriers during pregnancy?\",\"answer\":\"Prenatal testing can diagnose TS, including procedures such as amniocentesis or CVS. Results can help parents decide whether to continue the pregnancy, and families can also test after birth.\"}]","Tay-Sachs Disease - Positive Carrier Screening Result - Information Sheet | PDF",1790504855]