[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-427443-105":59,"doc-detail-427443-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","tau-positivity-did-not-correlate-with-phq9-depression-scores-in-a-memory-clinic","TAU POSITIVITY DID NOT CORRELATE WITH PHQ9 DEPRESSION SCORES IN A MEMORY CLINIC","","Background: Depression levels may or may not align with amyloid/tau biomarker positivity in memory clinic patients. Method: A retrospective correlation and multivariate regression analysis linked PHQ9 depression screening data with tau PET or tau blood positivity scores, adjusting for covariates including age, sex, education, and race. Results: Among 1043 attendees (2010–2025), only 20 had analyzable paired PHQ9 and tau blood results; tau positivity showed no significant association with PHQ9 in both univariate and multivariate models. Conclusions: PHQ9 screening depression scores were not affected by tau positivity as a binary outcome in this memory clinic setting.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/tau-positivity-did-not-correlate-with-phq9-depression-scores-in-a-memory-clinic/427443/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/tau-positivity-did-not-correlate-with-phq9-depression-scores-in-a-memory-clinic/427443.png","ImageObject",300,407,{"name":92,"@type":93},"Levi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-05","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main hypothesis of the study?","Question",{"text":112,"@type":113},"The study hypothesized a positive correlation between PHQ9-assessed depression levels and abnormal tau test results.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were depression and tau positivity measured?",{"text":117,"@type":113},"Depression screening used PHQ9, and tau positivity was measured using tau PET or tau blood test positivity scores, analyzed as a binary outcome.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the results show about the relationship between PHQ9 and tau positivity?",{"text":121,"@type":113},"Tau positivity did not correlate significantly with PHQ9, and the multivariate regression confirmed the lack of association after adjusting for age, sex, education, and race.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},427443,1790814295,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81},7971461740909,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Innovation in Aging, 2025, Vol. 9, No. S2 751  \nmemory clinic patients in the south shore of Boston from 2010 to 2025. We correlated depression screen data (PHQ9) to tau PET or Blood test positivity scores. Univariate analyses used Pearson correlation. A multivariate regression model analyzed PHQ9 to covariates of tau positivity, age, sex, education and race. Hypothesis: We hypothesized a positive correlation between depression levels scored by the PHQ9 and abnormal tau test results. Results: 1043 patients attended the memory clinic between 2010-2025; 20 had PHQ9 and tau blood test results with analyzable data. Patients were 58.9% female, 85.1 % White. Mean age was 70±14.2 years, Tau score did not correlate significantly to PHQ9 Multivariate model confirmed the lack of association of depression scores to tau abnormality (100000= 0.08, p = 0.44) . Conclusions: Depression scores using PHQ9 during screening were not affected by tau positivity as measured as a binary outcome during tau disclosure in a memory clinic.  \nAbstract citation ID: igaf122.2553  \nTAU POSITIVITY DID NOT CORRELATE WITH PHQ9  \nDEPRESSION SCORES IN A MEMORY CLINIC.  \nViviana Obando, Malini Nair, Rui Huang, Surya Sunil, Kavya Chemalapatti, and Anil Nair, ADC, Braintree, Massachusetts, United States  \nBackground: It is unknown if depression levels are correlated to positivity on tau blood or PET scan results in memory clinic patients. Method: We performed a retrospective analysis of","cbCaiaOsnD3F5RSz","https://ap.wps.com/l/cbCaiaOsnD3F5RSz","pdf",678029,"English","# Background\n## Method\n## Results\n## Conclusions","[{\"question\":\"What was the main hypothesis of the study?\",\"answer\":\"The study hypothesized a positive correlation between PHQ9-assessed depression levels and abnormal tau test results.\"},{\"question\":\"How were depression and tau positivity measured?\",\"answer\":\"Depression screening used PHQ9, and tau positivity was measured using tau PET or tau blood test positivity scores, analyzed as a binary outcome.\"},{\"question\":\"What did the results show about the relationship between PHQ9 and tau positivity?\",\"answer\":\"Tau positivity did not correlate significantly with PHQ9, and the multivariate regression confirmed the lack of association after adjusting for age, sex, education, and race.\"}]","TAU POSITIVITY DID NOT CORRELATE WITH PHQ9 DEPRESSION SCORES IN A MEMORY CLINIC | PDF",1790643866]