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Synchronous breast and colon cancers are rare and create major management challenges due to limited standardized guidance. A 73-year-old woman with a right breast mass was diagnosed with grade 2 invasive ductal carcinoma, while staging CT incidentally found ascending colon wall thickening. Colonoscopy and biopsy confirmed moderately differentiated invasive adenocarcinoma, and after neoadjuvant chemotherapy she underwent simultaneous radical mastectomy and right hemicolectomy. Postoperative recovery was uneventful and adjuvant chemoradiation followed multidisciplinary team recommendations.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/synchronous-primary-malignancies-incidental-detection-of-ascending-colon-adenocarcinoma-during-staging-of-invasive-ductal-carcinoma-of-the-breast/371404/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/synchronous-primary-malignancies-incidental-detection-of-ascending-colon-adenocarcinoma-during-staging-of-invasive-ductal-carcinoma-of-the-breast/371404.png","ImageObject",300,407,{"name":92,"@type":93},"Margaret","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",17,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What qualifies as multiple primary malignant neoplasms in this case?","Question",{"text":113,"@type":114},"MPMNs are defined as two or more histologically distinct tumors in the same individual. In this report, synchronous breast and colon cancers represent such a scenario.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the colon cancer detected during staging?",{"text":118,"@type":114},"Staging CT for the breast cancer incidentally revealed right colon wall thickening. Colonoscopy with biopsy then confirmed moderately differentiated invasive adenocarcinoma.",{"name":120,"@type":111,"acceptedAnswer":121},"What treatment approach was used for both cancers?",{"text":122,"@type":114},"After neoadjuvant chemotherapy, the patient underwent simultaneous radical mastectomy with axillary lymph node dissection and right hemicolectomy, followed by adjuvant chemoradiation based on multidisciplinary team input.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},371404,1790730719,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":52},137451207643,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Wiley  \nCase Reports in Oncological Medicine Volume 2025, Article ID 7164628, 4 pages [https://doi.org/10.1155/crom/7164628](https://doi.org/10.1155/crom/7164628)  \nCase Report  \nSynchronous Primary Malignancies: Incidental Detection of Ascending Colon Adenocarcinoma During Staging of Invasive Ductal Carcinoma of the Breast  \nSalif Balde, 1 Ulrich Igor Mbessoh Kengne , 1 Jaafar Ibn Abou Talib Thiam, 1,2 Joël Gabin Konlack Mekontso ,3 Sokhna Diop Niang,4 Amacoumba Fall, 1  \nMamadou Ndiaye, 1 Gorgui Sarr, 1 Etienne Tossou Zoure, 1 Mamadou Sow, 1 and Sidy Ka 1,2  \n1Department of Oncology, Dalal Jamm National Hospital Center, Dakar, Senegal  \n2Department of Surgery and Specialties, Faculty of Medicine, Pharmacy and Odontostomatology, Cheikh Anta Diop University, Dakar, Senegal  \n3Department of Internal Medicine, New York City Health and Hospitals South Brooklyn Health, Brooklyn, New York, USA 4Department of Internal Medicine, Dalal Jamm National Hospital Center, Dakar, Senegal  \nCorrespondence should be addressed to Ulrich Igor Mbessoh Kengne; [mbessohulrich@yahoo.com](mbessohulrich@yahoo.com)  \nReceived 15 January 2025; Accepted 19 February 2025  \nAcademic Editor: Jose I. Mayordomo  \nCopyright © 2025 Salif Balde et al. Case Reports in Oncological Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \nMultiple primary malignant neoplasms (MPMNs) are defined as two or more distinct tumors in the same individual. Synchronous breast and colon cancers are infrequent and present management challenges due to the lack of standardized guidelines. We report a 73-year-old woman presenting with a right breast mass, subsequently diagnosed as Grade 2 invasive ductal carcinoma. Staging CT incidentally revealed right colon wall thickening, and colonoscopy with biopsy confirmed moderately differentiated invasive adenocarcinoma. Following neoadjuvant chemotherapy, she underwent simultaneous radical mastectomy with axillary lymph node dissection and right hemicolectomy. Postoperative recovery was uneventful. Adjuvant chemoradiation was administered per multidisciplinary team (MDT) recommendation. Synchronous breast and colon cancers pose unique diagnostic and treatment planning challenges. MDT collaboration is crucial for personalized treatment strategies and optimized outcomes in these complex cases.  \nKeywords: breast cancer; colon cancer; multidisciplinary team meeting; multiple primary malignant neoplasms; synchronous primary malignancies  \n1. Introduction  \nMultiple primary malignant neoplasms (MPMNs), defined as two or more histologically distinct tumors in one individual [1–5], can be synchronous or metachronous, occurring in 0.7%–11% of patients [4–7] . A SEER database analysis (1988–2007) of 4835 women with breast and colon cancers reported a 3.8% frequency of synchronous cancers [2] . This represents, to our knowledge, the second documented casein Africa, as only one prior case has been formally published in the peer-reviewed literature [8] . BRCA1 and BRCA2 mutations play a significant role in the development of these  \ntumors [7] . The management of synchronous solid tumors is uniquely challenging due to the absence of standardized treatment protocols [6, 9, 10] . While established guidelines exist for individual malignancies, concurrent presentation complicates treatment decisions, particularly regarding surgical timing, feasibility of simultaneous resections, neoadjuvant therapy selection, and follow-up strategies [2, 9] . This report describes the case of a 73-year-old woman in Senegal diagnosed with synchronous invasive ductal carcinoma (IDC) of the breast and adenocarcinoma of the right colon. This case emphasizes the critical role of multidisciplinary team (MDT) collaboration in managing the complex  \n2 Case Reports in Oncological Medicine  \ncha","cbCaiucyxBePfuMs","https://ap.wps.com/l/cbCaiucyxBePfuMs","pdf",1176041,"English","# Introduction\n# Case Presentation","[{\"question\":\"What qualifies as multiple primary malignant neoplasms in this case?\",\"answer\":\"MPMNs are defined as two or more histologically distinct tumors in the same individual. In this report, synchronous breast and colon cancers represent such a scenario.\"},{\"question\":\"How was the colon cancer detected during staging?\",\"answer\":\"Staging CT for the breast cancer incidentally revealed right colon wall thickening. Colonoscopy with biopsy then confirmed moderately differentiated invasive adenocarcinoma.\"},{\"question\":\"What treatment approach was used for both cancers?\",\"answer\":\"After neoadjuvant chemotherapy, the patient underwent simultaneous radical mastectomy with axillary lymph node dissection and right hemicolectomy, followed by adjuvant chemoradiation based on multidisciplinary team input.\"}]","Synchronous Primary Malignancies - Incidental Detection of Ascending Colon Adenocarcinoma During Staging of Invasive Ductal Carcinoma of the Breast | PDF",1790191992]