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Background: Symptom science is advancing as symptom clusters and biologic mechanisms are better understood, yet brain-tumour patients have received insufficient attention. Design: A literature review using a systematic search strategy. Methods: Electronic databases were searched and findings were analyzed and synthesized. Findings: Four themes were identified covering theoretical foundations, validated assessment tools, reported symptom clusters and mechanisms, and evidence status of interventions.",{"@graph":69,"@context":126},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/symptom-management-in-adult-brain-tumours-a-literature-review/405860/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/symptom-management-in-adult-brain-tumours-a-literature-review/405860.png","ImageObject",300,407,{"name":92,"@type":93},"Maya Linwood","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118,122],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main purpose of the literature review?","Question",{"text":112,"@type":113},"The review aims to synthesize existing literature on symptom management for adults with brain tumours, focusing on clinical significance and related theoretical framework systems.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the evidence gathered and analyzed?",{"text":117,"@type":113},"The authors conducted a systematic literature review by searching electronic databases for published studies on symptom management in adults with brain tumours, then analyzing and synthesizing the relevant findings.",{"name":119,"@type":110,"acceptedAnswer":120},"What major themes were identified in the review?",{"text":121,"@type":113},"Four general themes were identified: theoretical foundations, validated assessment scales/questionnaires, symptom clusters with underlying biologic mechanisms, and symptom interventions categorized by evidence strength.",{"name":123,"@type":110,"acceptedAnswer":124},"What are the key implications for future symptom management research?",{"text":125,"@type":113},"Future work should use theoretical frameworks to guide research, study symptom clustering with common biologic mechanisms, and leverage modern big-data resources to strengthen the evidence base for effective interventions.","https://schema.org",{"og:url":83,"og:type":128,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":130,"canonical":83},"index,follow",{"doc_id":132,"site_id":62},405860,1790837541,{"code":4,"msg":5,"data":135},{"doc_id":132,"user_id":136,"nickname":92,"user_avatar":137,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":143,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149,"preview_page_count":4},962084928432,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","DOI: 10. 1002/nop2 .1795  \nR E V I E W A RTI C LE  \nSymptom management in adult brain tumours: A literature review  \nRong Zhang1,2  | Dong-Mei Wang2 | Yong-Li Liu3 | Man-Li Tian4 | Ling Zhu2 | Jing Chen2 | Jun Zhang1  \n1School of Nursing, Wuhan University, Wuhan, China  \n2Department of Neuro-Oncology Center, Taihe Hospital, Hubei University of Medicine, Shiyan, China  \n3 Nursing Department, Taihe Hospital, Hubei University of Medicine, Shiyan, China  \n4College of Nursing, Hubei University of Medicine, Shiyan, China  \nCorrespondence  \nJun Zhang, PhD, RN, Associate professor, School of Nursing, Wuhan University, No.  \n115, Donghu Road, Wuchang District, Wuhan 430071, Hubei, China.  \nEmail: [1528161351@qq.com](1528161351@qq.com)  \nFunding information  \nNatural Science Foundation of Hubei Province, Grant/Award Number:  \n2018CFB598  \nAbstract  \nAim: To review the literature related to symptom management, clinical significance and related theoretical framework systems in adult patients with brain tumours. Background: As understanding of symptoms or symptom clusters and underlying biologic mechanisms has grown, it is apparent that symptom science is moving forward. Although some progress has been made in the symptom science of solid tumours such as breast and lung neoplasms, insufficient attention has been paid to symptom management for patients suffering from brain tumours. Further research is needed to achieve effective symptom management for these patients.  \nDesign: A literature review with a systematic search of symptom management in adult brain tumours.  \nMethods: Electronic data bases were searched to obtain relevant published literature on symptom management in adults with brain tumours. This was then analysed and a synthesis of relevant findings is presented.  \nFindings: Four significant general themes relating to symptom management of brain tumours in adults were identified: (1) The potential theoretical foundation related to symptom management was revealed. (2) Widely accepted validated scales or questionnaires for the assessment of single symptoms or symptom clusters were recommended. (3) Several symptom clusters and the underlying biologic mechanisms have been reported. (4) Specific symptom interventions for adults with brain tumours were collected and classified as evidence-based or insufficient evidence.  \nConclusion: There are still many challenges in the effective management of symptoms in adults with brain tumours. The guiding role of theoretical frameworks or models related to symptom management should be utilized in future research. Using the concept of symptom clustering for research into symptoms found in patients with brain tumours, exploring common biological mechanisms for specific symptom clusters and making full use of modern big data resources to build a strong evidence base for an effective intervention or management program may inform the management of symptoms among these patients leading to better results.  \nRong Zhang, Dong-Mei Wang and Yong-Li Liu contributed equally to this work and share first authorship.  \nThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.  \n© 2023 The Authors. Nursing Open published by John Wiley & Sons Ltd.  \nNo Patient or Public Contribution: This is a literature review.  \nImplications for Symptom Management: The ultimate goal is obviously not only improving the survival rate of patients with brain tumours, but also enhancing their quality of life. Several important findings from our review include the theoretical foundations, validated assessment tools, the assessment of symptom clusters and the underlying biologic mechanism, and the identification of the evidence base for symptom interventions. These are of relevance for managers, researchers and practitioners and may functi","cbCaiiGwHB8bbCkN","https://ap.wps.com/l/cbCaiiGwHB8bbCkN","pdf",1448529,15,"English","# Introduction\n# Symptom management in adult brain tumours (literature review)\n## Aim and background\n## Design and methods\n## Key findings themes\n## Conclusion and implications","[{\"question\":\"What is the main purpose of the literature review?\",\"answer\":\"The review aims to synthesize existing literature on symptom management for adults with brain tumours, focusing on clinical significance and related theoretical framework systems.\"},{\"question\":\"How was the evidence gathered and analyzed?\",\"answer\":\"The authors conducted a systematic literature review by searching electronic databases for published studies on symptom management in adults with brain tumours, then analyzing and synthesizing the relevant findings.\"},{\"question\":\"What major themes were identified in the review?\",\"answer\":\"Four general themes were identified: theoretical foundations, validated assessment scales/questionnaires, symptom clusters with underlying biologic mechanisms, and symptom interventions categorized by evidence strength.\"},{\"question\":\"What are the key implications for future symptom management research?\",\"answer\":\"Future work should use theoretical frameworks to guide research, study symptom clustering with common biologic mechanisms, and leverage modern big-data resources to strengthen the evidence base for effective interventions.\"}]","Symptom management in adult brain tumours: A literature review | PDF",1790562166,38]