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This retrospective study compared post-airway involvement survival and overall survival between stent and conservative treatment groups, and evaluated prognostic factors. Results: Stenting improved PAIS and OS and reduced pneumonia-related mortality, with significant prognostic roles identified for stenting and subsequent anticancer therapy.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/survival-outcome-of-airway-stenting-in-patients-with-esophageal-cancer-with-airway-involvement/433598/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/survival-outcome-of-airway-stenting-in-patients-with-esophageal-cancer-with-airway-involvement/433598.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the purpose of comparing airway stenting versus conservative treatment?","Question",{"text":112,"@type":113},"To determine whether airway stenting improves survival outcomes compared with conservative management in advanced esophageal cancer patients with airway involvement.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were patients with airway involvement defined in the study?",{"text":117,"@type":113},"Airway involvement included airway obstruction with obstructive symptoms and esophago-respiratory fistulas.",{"name":119,"@type":110,"acceptedAnswer":120},"What survival outcomes and mortality differences were observed?",{"text":121,"@type":113},"Patients receiving airway stenting had significantly longer post-airway involvement survival and overall survival, and stenting significantly reduced pneumonia-related mortality compared with conservative treatment.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},433598,1790926093,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","J Chin MedAssoc  \nOriginal article  \nSurvival outcome of airway stenting in patients with esophageal cancer with airway involvement  \nChung-Yun Kuana, Chia Liua,b, Yi-Ying Leea, Hung-Che Chiena, Jung-Jyh Hunga,b, Chien-Sheng Huanga,b, Han-Shui Hsua,b, Po-Kuei Hsua,b,*  \naDivision of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; bDepartment of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC  \nAbstract  \nBackground: Airway stenting in patients with esophageal cancer involving the airway possibly improves survival by relieving the symptoms of obstructive pneumonitis and facilitating cancer treatment. However, its advantages over conservative management remain unclear. Therefore, we compared the survival outcomes of airway stenting and conservative treatment in patients with advanced esophageal cancer.  \nMethods: We retrospectively reviewed patients with advanced esophageal cancer involving the airway who were treated at Taipei Veterans General Hospital between July 2005 and January 2023. Airway involvement included airway obstruction with obstructive symptoms or esophago-respiratory fistulas. Patients were categorized into the stent and conservative treatment groups. We compared patients’ clinical characteristics, post-airway involvement survival (PAIS), and overall survival (OS) and assessed the prognostic factors for survival.  \nResults: A total of 52 patients, including 31 with airway stenting and 21 with conservative treatment, were included. No differences were observed between the two treatment groups in terms of age, sex, body mass index, clinical performance (Eastern Cooperative Oncology Group [ECOG]), tumor location, clinical N stage, or site of airway involvement. However, the conservative treatment group had more patients with clinical T4 stage (p \u003C 0.001) and M1 stage (p = 0.04) than did the stent group. PAIS (117 vs 43 days; p = 0.02) and OS (351 vs 106 days; p \u003C 0.001) were significantly longer in the stent group than in the conservative treatment group. In addition, airway stenting significantly reduced pneumonia-related mortality (9 .7% vs 52.4%; p = 0.001) . Multivariable analysis revealed anticancer treatment after airway involvement (hazard ratio [HR], 0. 13; confidence interval [CI], 0.06- 0.27; p \u003C 0 .001) and airway stenting (HR, 0.37; CI, 0.20-0.68; p = 0 .001) as significant prognostic factors for PAIS. For OS, ECOG ≥1 (HR, 2.20; CI, 1.09-4.42; p = 0.03) and airway stenting (HR, 0.37; CI, 0.17-0.78; p = 0.01) were significant prognostic factors. Conclusion: Airway stenting reduced pneumonia-related mortality in patients with advanced esophageal cancer with airway involvement. Moreover, patients who underwent airway stenting had better survival than did those who received conservative treatment alone; thus, airway stenting should be recommended after careful patient selection.  \nKeywords: Airway involvement; Airway stenting; Esophageal cancer; Overall survival; Post-airway involvement survival  \n692 [www.ejcma.org](www.ejcma.org)  \nOriginal Article. (2025) 88:9 J Chin MedAssoc  \nLay Summary: This study evaluated patients with advanced esophageal cancer involving the airway, causing issues such as obstructions or fistulas. Patients who received airway stenting lived longer and had a lower risk of mortality from pneumonia than those who received only supportive care. Further analysis showed that both airway stenting and additional cancer treatment after airway involvement were linked to better survival after airway issues. Airway stenting and a poorer general health status (ECOG ≥1) were important factors for overall survival. With careful selection of patients, airway stenting can be a useful treatment option.  \n1. INTRODUCTION  \nEsophageal cancer is the eighth most frequently diagnosed cancer and the sixth leading cause of cancer-related deaths worldwide.1 Poor outcomes are usually exacerbated when the tumor invades","cbCaiuK7yXNiIqYv","https://ap.wps.com/l/cbCaiuK7yXNiIqYv","pdf",1198513,"English","# Abstract\n# Introduction\n# Methods\n## Patients\n# Results\n# Conclusion","[{\"question\":\"What was the purpose of comparing airway stenting versus conservative treatment?\",\"answer\":\"To determine whether airway stenting improves survival outcomes compared with conservative management in advanced esophageal cancer patients with airway involvement.\"},{\"question\":\"How were patients with airway involvement defined in the study?\",\"answer\":\"Airway involvement included airway obstruction with obstructive symptoms and esophago-respiratory fistulas.\"},{\"question\":\"What survival outcomes and mortality differences were observed?\",\"answer\":\"Patients receiving airway stenting had significantly longer post-airway involvement survival and overall survival, and stenting significantly reduced pneumonia-related mortality compared with conservative treatment.\"}]","Survival outcome of airway stenting in patients with esophageal cancer with airway involvement | PDF",1790664749,23]