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Survival differs by tumor category, yet long-term trends for most types remain insufficiently characterized. Methods: Retrospective survival data were taken for Danish, Finnish, Norwegian, and Swedish patients from 1971–2020 using the NORDCAN database. Results: One- and five-year survival improved for all HN cancers, though only marginally for laryngeal cancer. Conclusions: Five-year survival reached ~65% for most HN cancers except hypopharyngeal; HPV is emerging as a dominant risk factor in rapidly increasing oropharyngeal cancer.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/survival-in-oral-and-pharyngeal-cancers-is-catching-up-with-laryngeal-cancer-in-the-nordic-countries-through-a-half-century/330033/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/survival-in-oral-and-pharyngeal-cancers-is-catching-up-with-laryngeal-cancer-in-the-nordic-countries-through-a-half-century/330033.png","ImageObject",300,407,{"name":92,"@type":93},"Logic","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Which head and neck cancer types were studied and over what period?","Question",{"text":112,"@type":113},"The study focuses on selected head and neck cancers (including oral, nasopharyngeal, oropharyngeal, hypopharyngeal, and laryngeal) using retrospective data from Denmark, Finland, Norway, and Sweden from 1971 to 2020.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did survival change over time for head and neck cancers?",{"text":117,"@type":113},"Both one- and five-year survival improved across head and neck cancers, but the improvement was only marginal for laryngeal cancer.",{"name":119,"@type":110,"acceptedAnswer":120},"Why is human papillomavirus (HPV) important for oropharyngeal cancer in this context?",{"text":121,"@type":113},"The document states that HPV infection is becoming a dominant risk factor for the increasing incidence of oropharyngeal cancer, and that prevention needs to emphasize oral sex as a route of infection.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},330033,1790113095,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},1099513958762,"https://ap-avatar.wpscdn.com/avatar/1000023916a998db790?x-image-process=image/resize,m_fixed,w_180,h_180&k=1784791008015729253","DOI: 10. 1002/cam4 .6867  \nRESEAR CH ARTICLE  \nSurvival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century  \nFrantisek Zitricky1  | Anni I. Koskinen2 | Otto Hemminki3,4 | Asta Försti5,6 | Akseli Hemminki4,7  | Kari Hemminki1,8   \n1Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic 2Department of OtorhinolaryngologyHead and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland 3Department of Urology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland  \n4Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, Helsinki, Finland  \n5Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany 6Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany 7Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland  \n8Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany  \nCorrespondence  \nKari Hemminki, Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, 30605 Pilsen, Czech Republic. [Email:](Email: k.hemminki@dkfz.de)[ k.hemminki@dkfz.de](Email: k.hemminki@dkfz.de)  \nFunding information  \nEuropean Union's Horizon 2020, grant no. 856620 (Chaperon)  \nAbstract  \nBackground: Cancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies by individual tumor type but for most of them survival trends are not well known over extended periods of time.  \nMethods: Data for a retrospective survival study were obtained for Danish, Finnish, Norwegian, and Swedish patients from the NORDCAN database from 1971 to 2020. Relative 1-and 5-year survival rates and 5/1-year conditional survival for years 2–5 were calculated.  \nResults: Both 1-and 5-year survival improved for all HN cancers but only marginally for laryngeal cancer. For the other cancers a 50-year increase in 5-year survival was about 30% units for nasopharyngeal and oropharyngeal cancers, 20% units for oral cancer and somewhat less for hypopharyngeal cancer. Conclusions: 5-year survival reached about 65% for all HN cancers, except for hypopharyngeal cancer (30%) . Human papilloma virus infection is becoming a dominant risk factor for the rapidly increasing oropharyngeal cancer, the prevention of which needs to emphasize oral sex as a route of infection.  \nKEYWORDS  \nconditional survival, human papilloma virus, oral cancer, pharyngeal cancer  \nThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \n© 2023 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.  \n1 | INTRODUCTION  \nCancers ofthe head and neck (HN) in anatomic sequence include, oral (oral cavity), nasopharyngeal, oropharyngeal, hypopharyngeal, and laryngeal cancers of the upper aerodigestive tract.1 These cancers are predominantly squamous cell carcinomas and their incidence is generally higher in men compared to women for which the common risks factors of tobacco smoking, alcohol intake and their interactions are at least a partial explanation.2,3 The relative risk of these cancers in active smoker is of the order of 10–15, but the risk is thought be lower (less than 2) for nasopharyngeal cancer.2,4 While the overall risk of smoking may be somewhat lower for these cancers than it is for lung cancer, the positive influence of quitting smoking appears to be faster than that for lung cancer, and after 10 years of quitting the excess risk may have disappeared.2 The main risk factor for oropharyngeal cancers in industrialized countries is infection with human papillomavirus","cbCaiguG3OtGZ1ql","https://ap.wps.com/l/cbCaiguG3OtGZ1ql","pdf",10931331,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Introduction","[{\"question\":\"Which head and neck cancer types were studied and over what period?\",\"answer\":\"The study focuses on selected head and neck cancers (including oral, nasopharyngeal, oropharyngeal, hypopharyngeal, and laryngeal) using retrospective data from Denmark, Finland, Norway, and Sweden from 1971 to 2020.\"},{\"question\":\"How did survival change over time for head and neck cancers?\",\"answer\":\"Both one- and five-year survival improved across head and neck cancers, but the improvement was only marginal for laryngeal cancer.\"},{\"question\":\"Why is human papillomavirus (HPV) important for oropharyngeal cancer in this context?\",\"answer\":\"The document states that HPV infection is becoming a dominant risk factor for the increasing incidence of oropharyngeal cancer, and that prevention needs to emphasize oral sex as a route of infection.\"}]","Survival in Oral and Pharyngeal Cancers is Catching Up with Laryngeal Cancer in the NORDIC Countries Through a Half Century | PDF",1789986636,25]