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Methods: Retrospective and prospective cohort of synchronous colorectal cancer patients undergoing surgery or endoscopic resection between 2008 and 2019; all received at least two surveillance colonoscopies within 2 years, with univariate and multivariate analyses. Results: 55.3% developed metachronous adenoma and 2 had metachronous carcinomas. Conclusion: Postoperative surveillance strategies should be individualized by sex, baseline colonoscopy findings, and the resection approach.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/surveillance-colonoscopies-of-synchronous-colorectal-cancer-what-should-we-do/375522/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/surveillance-colonoscopies-of-synchronous-colorectal-cancer-what-should-we-do/375522.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the primary aim of this study?","Question",{"text":112,"@type":113},"To assess the occurrence of metachronous neoplasms at 2-year surveillance colonoscopy in synchronous colorectal cancer patients and to determine relative risk factors.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were patients selected for surveillance colonoscopy?",{"text":117,"@type":113},"Patients with synchronous colorectal cancer who underwent surgery or endoscopic treatment between January 2008 and December 2019 were enrolled, and each underwent at least two surveillance colonoscopies within 2 years after operation.",{"name":119,"@type":110,"acceptedAnswer":120},"Which factors were identified as independent risk factors during follow-up?",{"text":121,"@type":113},"Presence of synchronous adenomas at baseline colonoscopy was an independent risk factor for metachronous adenoma during follow-up (odds ratio 15.0; 95% CI 1.55-145.22).","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},375522,1790525100,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","ORIGINAL ARTICLE GASTROINTESTINAL ENDOSCOPY  \nSurveillance Colonoscopies of Synchronous Colorectal Cancer: What Should We Do?  \nChunmei Guo1, Jing Wu1,2, Yadan Wang1, Hui Su1, Canghai Wang1, Hong Liu1 1Gastroenterology Department, Beijing Shijitan Hospital, Capital Medical University, Beijing, China  \n2Gastroenterology Department, Beijing Friendship Hospital, Capital Medical University, Beijing, China  \nCite this article as: Guo C, Wu J, Wang Y, Su H, Wang C, Liu H. Surveillance colonoscopies of synchronous colorectal cancer: What should we do? Turk J Gastroenterol. 2023;34(3):234-241.  \nABSTRACT  \nBackground: The aim of this study is to investigate the occurrence of metachronous neoplasms at 2-year surveillance colonoscopy for synchronous colorectal cancer patients and the relative risk factors.  \nMethods: Synchronous colorectal cancer patients who underwent surgery or endoscopic resection for colorectal cancer between January 2008 and December 2019 were enrolled. All patients underwent surveillance colonoscopies at least twice within 2 years after operation. Univariate and multivariate analyses were conducted to assess the risk factors for the metachronous neoplasms.  \nResults: Totally 38 patients (male/female: 26/12) were included, with an average age of 64.6 years (±11.5 years) and a mean surveillance interval of 23.47 ± 4.39 months. In 21 of 38 patients (55.3%), metachronous adenoma was detected, including 6 metachronous advanced adenomas. Two patients were detected with metachronous carcinomas. In univariate analysis, male sex, elderly age at diagnosis, and the presence of synchronous adenomas/synchronous advanced adenoma at baseline colonoscopy were associated with the development of metachronous adenoma (P = . 037, . 047, . 013, . 039), but not associated with metachronous advanced adenoma (P = 0.455, . 746, .503, .269). Patients tends to occur less metachronous advanced adenoma if index colorectal tumors were treated by endoscopic resection (P = .010), but the tendency was not discovered in metachronous adenoma (P = .289). Tumor location (with/ without rectum cancer) was not associated with the development of metachronous lesions (P = .526, .382). On multivariate analysis, the presence of synchronous adenomas at baseline colonoscopy was an independent risk factor for MA during follow-up (odds ratio = 15. 0; 95% CI: 1.55-145.22).  \nConclusion: For postoperative synchronous colorectal cancer patients, doctors should design individual surveillance strategies according to sex, baseline colonoscopy, and operative (or endoscopic) approach of resection.  \nKeywords: Clinicopathological characteristics, metachronous adenoma, metachronous advanced adenoma, surveillance colonoscopies, synchronous colorectal cancer  \nINTRODUCTION  \nColorectal cancer (CRC) is the third most common cancer worldwide.1 Synchronous colorectal carcinoma (SCRC) refers to more than 1 primary colorectal carcinoma detected in a single patient at initial presentation. The prevalence of SCRC is approximately 3 . 5% of all colorectal carcinomas.2 Over recent years, with the improvement of colonoscopy technology, many early-stage colorectal cancers were diagnosed and treated by endoscopy (endoscopic mucosal resection [EMR] or endoscopic submucosal dissection [ESD]) . Studies showed that, different from solitary colorectal carcinoma, SCRC was significantly associated with poor prognosis.2 Though postoperative endoscopic surveillance has become a routine part of clinical practice, studies are lacking for those SCRC patients. Considering that most epidemiological studies indicate a higher incidence of metachronous adenoma  \n(MA) in the initial 2-3 years following surgery, and significantly decreased thereafter,3,4 we aimed to assess the occurrence of metachronous neoplasms at 2-year surveillance colonoscopy for SCRC patients and the relative risk factors.  \nMATERIALS AND METHODS  \nStudy Population  \nIn this retrospective and prospective cohort study, SCRC patient","cbCaiuIn2heGg82M","https://ap.wps.com/l/cbCaiuIn2heGg82M","pdf",1060432,"English","# Abstract\n# Introduction\n# Materials and Methods\n## Study Population","[{\"question\":\"What was the primary aim of this study?\",\"answer\":\"To assess the occurrence of metachronous neoplasms at 2-year surveillance colonoscopy in synchronous colorectal cancer patients and to determine relative risk factors.\"},{\"question\":\"How were patients selected for surveillance colonoscopy?\",\"answer\":\"Patients with synchronous colorectal cancer who underwent surgery or endoscopic treatment between January 2008 and December 2019 were enrolled, and each underwent at least two surveillance colonoscopies within 2 years after operation.\"},{\"question\":\"Which factors were identified as independent risk factors during follow-up?\",\"answer\":\"Presence of synchronous adenomas at baseline colonoscopy was an independent risk factor for metachronous adenoma during follow-up (odds ratio 15.0; 95% CI 1.55-145.22).\"}]","Surveillance Colonoscopies of Synchronous Colorectal Cancer - What Should We Do? | PDF",1790215243]