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This article reviews management strategies and evaluates evidence for different surgical approaches.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/surgical-management-of-splenic-flexure-colonic-malignancy-minireviews/406634/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/surgical-management-of-splenic-flexure-colonic-malignancy-minireviews/406634.png","ImageObject",300,407,{"name":42,"@type":43},"Aran","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",8,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"Why is there no consensus on the optimal surgery for splenic flexure malignancies?","Question",{"text":63,"@type":64},"Variability in lymphatic and vascular anatomy of the splenic flexure creates uncertainty about the appropriate extent of resection and lymphadenectomy.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What surgical options are commonly discussed for splenic flexure malignancies?",{"text":68,"@type":64},"Approaches include conservative segmental resection as well as extended resections such as extended right or left hemicolectomy, depending on the intended oncologic strategy.",{"name":70,"@type":61,"acceptedAnswer":71},"What does the article say about the evidence supporting conservative surgery?",{"text":72,"@type":64},"Most supportive data for segmental resection comes from retrospective single-center studies, despite an increasing body of evidence suggesting oncological safety.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},406634,1791263128,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":111,"show_sort_weight":112,"slug":113},"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":139,"language":140,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":12,"update_tm":144,"read_time":145,"preview_page_count":4},137455076865,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","| W | J | G | S | World Journal of\u003Cbr>Gastrointestinal Surgery |\n| --- | --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Surg 2025 December 27; 17(12): 111582  \nDOI: 10.4240/wjgs.v17.i12.111582 ISSN 1948-9366 (online)  \nMINIREVIEWS  \nSurgical management of splenic flexure colonic malignancy  \nSabrina Hui-Xian Cheok, Salman Ahmed Abdul Jabbar, Neng-Wei Wong, James Chi-Yong Ngu, Nan-Zun Teo  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade B, Grade C  \nNovelty: Grade B, Grade B  \nCreativity or Innovation: Grade B, Grade B  \nScientific Significance: Grade B, Grade B  \nP-Reviewer: Rath S, MD, Researcher, India  \nReceived: July 3, 2025  \nRevised: August 6, 2025  \nAccepted: October 9, 2025  \nPublished online: December 27, 2025  \nProcessing time: 175 Days and 1 Hours  \nSabrina Hui-Xian Cheok, Salman Ahmed Abdul Jabbar, Neng-Wei Wong, James Chi-Yong Ngu, Nan-Zun Teo, Department of General Surgery, Changi General Hospital, Singapore 529889, Singapore  \nCorresponding author: Nan-Zun Teo, Department of General Surgery, Changi General Hospital, 2 Simei Street 3, Singapore 529889, [Singapore.](Singapore. teo.nan.zun@singhealth.com.sg)[ teo.nan.zun@singhealth.com.sg](Singapore. teo.nan.zun@singhealth.com.sg)  \nAbstract  \nThere is a lack of consensus on the optimal surgical approach for splenic flexure malignancies. Surgeons face the challenge of balancing successful oncological outcomes with the morbidity and functional effects of extended colonic resection, considering the variable ‘watershed’ vasculature and lymphatic anatomy of thesplenic flexure. While there is an increasing body of evidence supporting the oncological safety of a more conservative segmental resection, most of the data stems from retrospective single center studies. This article reviews the management strategies and examines the evidence supporting various surgical approaches to splenic flexure malignancies.  \nKey Words: Colonic malignancy; Surgical approach; Splenic flexure malignancy; Extended right hemicolectomy; Left hemicolectomy; Segmental resection; Splenic flexure cancer  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \nCore Tip: There are several studies in current literature discussing the optimal surgical approach for splenic flexure malignancies. However, these studies are mainly retrospective and performed in single centers. The variability in the vascular and lymphatic anatomy of the splenic flexure coupled with the lack of international standardization in the terminology for oncologic resections makes management challenging. This article reviews the various management strategies in the literature and examines the evidence supporting various surgical approaches to splenic flexure malignancies.  \nCitation: Cheok SHX, Jabbar SAA, Wong NW, Ngu JCY, Teo NZ. Surgical management ofsplenic flexure colonic malignancy. World J Gastrointest Surg 2025; 17(12): 111582  \nURL: [https://www.wjgnet.com/1948-9366/full/v17/i12/111582.htm](https://www.wjgnet.com/1948-9366/full/v17/i12/111582.htm)  \nDOI: [https://dx.doi.org/10.4240/wjgs.v17.i12.111582](https://dx.doi.org/10.4240/wjgs.v17.i12.111582)  \n WJGS  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 27, 2025  Volume 17  Issue 12   \nCheok SHX et al. Surgical management of SFM  \nINTRODUCTION  \nStandard anatomical resection for right and left-sided colon malignancy is well established, however there is ongoing debate regarding the optimal surgical strategy for splenic flexure malignancies (SFMs)[1-3] . This ambiguity exists due to the variable lymphatic and vascular anatomy of the splenic flexure [4] . The American Society of Colon and Rectal Surgeons highlight that SFM require specific consideration regarding what constit","cbCaihJqYjlb0cgs","https://ap.wps.com/l/cbCaihJqYjlb0cgs","pdf",3069063,11,"English","# INTRODUCTION\n# LITERATURE REVIEW\n# DEFINITION OF SPLENIC FLEXURE AND RELEVANT ANATOMY","[{\"question\":\"Why is there no consensus on the optimal surgery for splenic flexure malignancies?\",\"answer\":\"Variability in lymphatic and vascular anatomy of the splenic flexure creates uncertainty about the appropriate extent of resection and lymphadenectomy.\"},{\"question\":\"What surgical options are commonly discussed for splenic flexure malignancies?\",\"answer\":\"Approaches include conservative segmental resection as well as extended resections such as extended right or left hemicolectomy, depending on the intended oncologic strategy.\"},{\"question\":\"What does the article say about the evidence supporting conservative surgery?\",\"answer\":\"Most supportive data for segmental resection comes from retrospective single-center studies, despite an increasing body of evidence suggesting oncological safety.\"}]","Surgical management of splenic flexure colonic malignancy - minireviews | PDF",1790566844,28]