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The review applies PRISMA-P 2015 search and selection methods across MEDLINE/PubMed, Google Scholar, and Ovid Embase, restricting included studies to English publications from 2000 onward. Thirty-three studies totaling 154 patients are synthesized, focusing on epidemiology, imaging findings, surgical approaches, outcomes, and complications.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/surgical-management-of-sellar-arachnoid-cyst-state-of-the-art-and-systematic-review/413030/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/surgical-management-of-sellar-arachnoid-cyst-state-of-the-art-and-systematic-review/413030.png","ImageObject",300,407,{"name":92,"@type":93},"WPS_1790064749","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main objective of this systematic review?","Question",{"text":112,"@type":113},"To consolidate current knowledge on the epidemiology, radiological features, surgical management, and outcomes of sellar arachnoid cysts.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which studies and databases were included in the review?",{"text":117,"@type":113},"A literature search followed PRISMA-P 2015 guidelines and searched MEDLINE/PubMed, Google Scholar, and Ovid Embase, including English studies published from 2000 onward.",{"name":119,"@type":110,"acceptedAnswer":120},"What surgical approach was most commonly reported, and what complication was most frequent?",{"text":121,"@type":113},"Endoscopic transsphenoidal surgery was the most frequent approach. 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Neurol. 16:1681774 .  \ndoi: 10.3389/fneur.2025.1681774  \nCOPYRIGHT  \n© 2025 Fabrizio, Jannelli, Calvanese, Delaidelli, Cardia, Momjian, Manet, Jouanneau and Milani. This is an open-access article distributed under the terms of the  \nCreative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.  \nSurgical management of sellararachnoid cyst: state of the art and systematic review  \nMichele Pio Fabrizio1,2*, Gianpaolo Jannelli3,  \nFrancesco Calvanese4, Alberto Delaidelli 5,6, Andrea Cardia 1, Shahan Momjian3, Romain Manet7, Emmanuel Jouanneau7,8 and Davide Milani 1  \n1Department of Neurosurgery, Neurocenter of Southern Switzerland, EOC, Lugano, Switzerland, 2Department of Neurosurgery, Kantonsspital Winterthur, Winterthur, Switzerland, 3Department of Neurosurgery, Geneva University Hospitals, University of Geneva Faculty of Medicine, Geneva, Switzerland, 4Department of Spinal and Robotic Surgery, Humanitas San Pio X Hospital, Milan, Italy, 5Department of Pathology, Mass General Brigham, Harvard Medical School, Boston, MA, United States, 6Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada, 7Department of Cranial Neurosurgery, Pierre Weithermier Neurological Hospital, Bron, France, 8Hôpital Neurologique et Neurochirurgical Pierre Wertheimer, Lyon, France  \nIntroduction: Sellar arachnoid cysts are rare intracranial lesions with variable clinical presentations, making their optimal management uncertain. This systematic review consolidates current knowledge on their epidemiology, radiological features, surgical management, and outcomes.  \nMaterials and methods: A literature search, following PRISMA-P 2015 guidelines, was conducted in MEDLINE/PubMed, Google Scholar, and Ovid Embase. Studies published in English from the year 2000 onwards were included. Data extraction focused on patient demographics, clinical presentation, surgical approaches, outcomes, and complications.  \nResults: Thirty-three studies (16 case reports, 17 case series) met the inclusion criteria, encompassing 154 patients (59.34% female, mean age 51.48 years) . The most common symptoms were visual disturbances (57. 14%), headaches (35 .06%), and endocrine disorders (30 . 52%) . Surgical intervention details were available for 144 patients. Endoscopic transsphenoidal surgery was the most frequent approach (73 .38%), followed by microscopic transsphenoidal surgery (11 .69%) . Various sellar reconstruction techniques were employed, including fascia lata, abdominal fat grafts, and nasoseptal flaps. The mean follow-up was 42.90 months. Postoperative complications occurred in 15. 58% of cases, with cerebrospinal fluid leaks (7. 14%) being the most common. Cyst recurrence was observed in 6.49% of patients. Most individuals with visual disturbances and headaches improved postoperatively, while endocrine function recovery was les","cbCaieLLS4sDYeOo","https://ap.wps.com/l/cbCaieLLS4sDYeOo","pdf",1162832,17,"English","# Introduction\n# Materials and methods\n# Results\n# Discussion and conclusions\n# Keywords","[{\"question\":\"What is the main objective of this systematic review?\",\"answer\":\"To consolidate current knowledge on the epidemiology, radiological features, surgical management, and outcomes of sellar arachnoid cysts.\"},{\"question\":\"Which studies and databases were included in the review?\",\"answer\":\"A literature search followed PRISMA-P 2015 guidelines and searched MEDLINE/PubMed, Google Scholar, and Ovid Embase, including English studies published from 2000 onward.\"},{\"question\":\"What surgical approach was most commonly reported, and what complication was most frequent?\",\"answer\":\"Endoscopic transsphenoidal surgery was the most frequent approach. Cerebrospinal fluid leaks were the most common postoperative complication.\"}]","Surgical management of sellar arachnoid cyst: state of the art and systematic review | PDF",1790593588,43]