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This pilot randomized controlled trial protocol evaluates the 7-month effects of a supervised 16-week multicomponent exercise programme in adults aged 18–55. Forty participants receiving active treatment or up to 5 years post-treatment will be randomized to experimental or control groups, with training three times per week. Outcomes include quality of life, sexual function, stress-response strategies, nutrition, physical functions, and body composition, alongside physiological changes in inflammation, metabolism, muscle adaptation, and cellular aging.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/supervised-16-week-multicomponent-exercise-training-programme-for-1855-year-old-people-living-with-and-beyond-cancer-consort-2025-based-study-protocol-of-the-pilot-onco-move-randomized-controlled-trial/466868/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/supervised-16-week-multicomponent-exercise-training-programme-for-1855-year-old-people-living-with-and-beyond-cancer-consort-2025-based-study-protocol-of-the-pilot-onco-move-randomized-controlled-trial/466868.png","ImageObject",300,407,{"name":92,"@type":93},"Franzy","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the purpose of the Onco-Move pilot randomized controlled trial?","Question",{"text":112,"@type":113},"The trial aims to investigate the 7-month effects of a supervised 16-week multicomponent exercise programme in adults living with and beyond cancer.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Who can participate in the study and how many participants are included?",{"text":117,"@type":113},"The study includes 40 participants aged 18–55 who are either undergoing cancer treatment or are up to 5 years post-treatment, with different cancer types.",{"name":119,"@type":110,"acceptedAnswer":120},"What outcomes and physiological changes are expected from the exercise programme?",{"text":121,"@type":113},"The programme is expected to improve quality of life, sexual function, stress-response strategies, nutrition, physical functions, and body composition, and to induce physiological changes related to inflammation, metabolism, muscle adaptation, and cellular aging.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},466868,1791153148,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},2336478945519,"https://ap-avatar.wpscdn.com/davatar_085a072bc5b1113ac321206ff7593b45","Protocol  \nSupervised 16-Week Multicomponent Exercise Training Programme for 18–55-Year-Old People Living with and Beyond Cancer—CONSORT 2025-Based Study Protocol of the Pilot Onco-Move Randomized Controlled Trial  \nMarzena Wieczorek-Przybyło 1, *, Milena Lachowicz 2, Maja Tomczyk 3, Agnieszka Kowalska 3, Mateusz Sprengel 4, Jakub Szczubełek 5, Michał Nied´zwiecki 4, Wojciech Barton 4, Bartłomiej Zyborowicz 5 and David Jiménez-Pavón 6  \nAcademic Editor: Debasis Bagchi  \nReceived: 26 November 2025  \nRevised: 24 December 2025  \nAccepted: 26 December 2025  \nPublished: 27 December 2025  \nCopyright: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 Department of Psychology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland  \n2 Department and Clinic of Oncology and Radiotherapy, Medical University of Gdansk, 80-210 Gdansk, Poland; [milena.lachowicz@gumed.edu.pl](milena.lachowicz@gumed.edu.pl)  \n3 Department of Biochemistry, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland; [maja.tomczyk@awf.gda.pl](maja.tomczyk@awf.gda.pl) (M.T.); [agnieszka.kowalska@awf.gda.pl](agnieszka.kowalska@awf.gda.pl) (A.K.)  \n4 Department of Physiology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland; [mateusz.sprengel@awf.gda.pl](mateusz.sprengel@awf.gda.pl) (M.S.); [michalniedwied@gmail.com](michalniedwied@gmail.com) (M.N.); [wojciech.barton@awf.gda.pl](wojciech.barton@awf.gda.pl) (W.B.)  \n5 Independent Researcher, 80-000 Gdansk, Poland; [jakubszczubelek@wp.pl](jakubszczubelek@wp.pl) (J.S.);  \n[zyborowiczb@gmail.com](zyborowiczb@gmail.com) (B.Z.)  \n6 MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences and Biomedical Research Innovation Institute of Cádiz, University of Cádiz, 11519 Cadiz, Spain; david.jimenez@uca.es  \n* [Correspondence: marzena.wieczorek-przybylo@awf.gda.pl](Correspondence: marzena.wieczorek-przybylo@awf.gda.pl)  \nAbstract  \nDespite evidence that exercise improves treatment outcomes, most people living with and beyond cancer (PLWBC) are insufficiently physically active. To address this challenge the Onco-Move Improvement of psychophysical fitness in adult cancer survivors pilot randomized controlled trial aims to investigate the 7-month effects of a 16-week supervised, multicomponent exercise programme on PLWBC adults aged 18–55 . The study will include 40 participants currently undergoing cancer treatment or up to 5 years post-treatment with different types of cancer, who will be randomly assigned to the experimental or the control group. The exercise programme will take place three times a week for 16 weeks. We hypothesize that the Onco-Move exercise programme will improve participants’ quality of life, sexual function, and stress-response strategies, as well as their nutrition, physical functions, and body composition. We also expect to observe physiological changes related to the intervention influencing inflammation, metabolism, muscle adaptation, and cellular aging. The Onco-Move exercise programme, once validated, has the potential to be implemented in oncological non-governmental organizations (NGOs) and hospitals in Poland and Spain, among others, as a feasible, effective, and safe non-pharmacological aid for cancer patients and survivors.  \nKeywords: cancer; cancer exercise; exercise; cancer survivors; physical activity interventions; exercise programmes; quality of life  \n1. Introduction  \nCancer accounted for nearly 20 million new cases and 10 million deaths in 2022 [1] . Estimates suggest that approximately one in five men or women will develop cancer in their  \nlifetime, whereas around one in nine men and one in twelve women will die from it [1] . The number of diagnoses is also increasing among younger adults [2] . One-fourth of new incidents in 2022 occurred among people a","cbCaifbrjGMQc72j","https://ap.wps.com/l/cbCaifbrjGMQc72j","pdf",1106450,17,"English","# Abstract\n# Introduction","[{\"question\":\"What is the purpose of the Onco-Move pilot randomized controlled trial?\",\"answer\":\"The trial aims to investigate the 7-month effects of a supervised 16-week multicomponent exercise programme in adults living with and beyond cancer.\"},{\"question\":\"Who can participate in the study and how many participants are included?\",\"answer\":\"The study includes 40 participants aged 18–55 who are either undergoing cancer treatment or are up to 5 years post-treatment, with different cancer types.\"},{\"question\":\"What outcomes and physiological changes are expected from the exercise programme?\",\"answer\":\"The programme is expected to improve quality of life, sexual function, stress-response strategies, nutrition, physical functions, and body composition, and to induce physiological changes related to inflammation, metabolism, muscle adaptation, and cellular aging.\"}]","Supervised 16-Week Multicomponent Exercise Training Programme for 18–55-Year-Old People Living with and Beyond Cancer - CONSORT 2025-Based Study Protocol of the Pilot Onco-Move Randomized Controlled Trial | PDF",1790771971,43]