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Two experimental studies test whether counter-stereotypical portrayals reduce distrust and whether individuals with substance use histories receive less informational support from close networks. Across scenarios, participants show reduced trust toward people with substance abuse histories. Counter-stereotypical information helps only in property-related risk contexts and family requests trigger lower informational support.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/substance-use-stigma-reduces-trust-and-informational-support-experimental-evidence-across-risk-and-relationship-contexts/422551/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/substance-use-stigma-reduces-trust-and-informational-support-experimental-evidence-across-risk-and-relationship-contexts/422551.png","ImageObject",300,407,{"name":92,"@type":93},"A glass of water","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How does addiction history affect interpersonal trust in the experiments?","Question",{"text":112,"@type":113},"Participants showed significantly reduced trust toward individuals with a history of substance abuse across both hypothetical scenarios.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Can positive or counter-stereotypical portrayals reduce distrust?",{"text":117,"@type":113},"Counter-stereotypical information significantly reduced distrust in the property-related risk scenario, but did not measurably change trust in personal risk contexts.",{"name":119,"@type":110,"acceptedAnswer":120},"What type of social support is reduced for people with substance use histories?",{"text":121,"@type":113},"Individuals with substance use histories received less informational support when assistance was requested by family members.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},422551,1790812769,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090760832,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Flores Martínez Harm Reduction Journal (2026) 23:1 Harm Reduction Journal  \n[https://doi.org/10.1186/s12954-025-01334-5](https://doi.org/10.1186/s12954-025-01334-5)  \nRESEARCH Open Access  \nSubstance use stigma reduces trust   \nand informational support: experimental evidence across risk and relationship contexts  \nIván Flores Martínez 1*  \nAbstract  \nBackground This study investigates the impact of addiction history on interpersonal trust and access to social support. Specifically, it explores whether people exhibit decreased trust toward individuals with addiction histories, explores the extent to which positive portrayal s can mitigate such distrust, and evaluates whether those with addiction histories receive reduced social support from their closest social networks, including friends and family. Methods Two complementary studies were conducted. Study 1 employed hypothetical scenarios to assess trust in both property-related and personal risk situations and examined whether counter-stereotypical information could reduce distrust. Study 2 used vignettes depicting individuals seeking assistance in differing relational contexts (friends versus family) to evaluate responses and types of support provided. Ordinary Least Squares (OLS) regression was applied to estimate the effects of experimental manipulations on trust and social support.  \nResults Participants exhibited significantly reduced trust toward individuals with a history of substance abuse across both scenarios. Providing counter-stereotypical information significantly reduced distrust in the property risk scenario, but had no measurable effect on trust in personal risk contexts. Regarding social support, individuals with substance use histories received less informational support when assistance was requested by family members.  \nConclusions This research highlights the role of addiction stigma in shaping interpersonal dynamics, particularly intrust and social support. The findings suggest that targeted interventions addressing trust deficits, such as counterstereotypical portrayal s or trust-building programs, could play a role in reducing stigma and enhancing interpersonal relationships. Additionally, mentoring programs and improved access to informational resources may help bridge gaps in social support, especially where family support is limited. These insights have significant implications for rehabilitation programs, family support services, and community-based initiatives aimed at promoting successful recovery and reintegration.  \nKeywords Substance use stigma, Interpersonal trust, Social support, Counter-stereotypical information, Risk contexts, Relationship contexts, Informational support, Addiction history  \n*Correspondence:  \nIván Flores Martínez  \n[ifloresm@charlotte.edu](ifloresm@charlotte.edu)  \n1University of North Carolina at Charlotte, Charlotte, USA  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creati](http://creati)[vecommons.org/l](vecommons.org/l)icenses/by-nc-nd/4.0/.  \nFlores Martínez Harm Reduction Journ","cbCaidbFy8JcN6Py","https://ap.wps.com/l/cbCaidbFy8JcN6Py","pdf",1804225,13,"English","# Abstract\n# Introduction\n# Methods\n## Study 1\n## Study 2\n# Results\n# Conclusions","[{\"question\":\"How does addiction history affect interpersonal trust in the experiments?\",\"answer\":\"Participants showed significantly reduced trust toward individuals with a history of substance abuse across both hypothetical scenarios.\"},{\"question\":\"Can positive or counter-stereotypical portrayals reduce distrust?\",\"answer\":\"Counter-stereotypical information significantly reduced distrust in the property-related risk scenario, but did not measurably change trust in personal risk contexts.\"},{\"question\":\"What type of social support is reduced for people with substance use histories?\",\"answer\":\"Individuals with substance use histories received less informational support when assistance was requested by family members.\"}]","Substance use stigma reduces trust and informational support - experimental evidence across risk and relationship contexts | PDF",1790627925,33]