[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-31781":3,"doc-seo-31781":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},31781,7971461740909,"Levi","https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d",7,"Healthcare","Study on the Combination of Remimazolam Besylate and Sufentanil in Elderly Patients with Percutaneous Vertebroplasty","A randomized study evaluates the clinical application effect of remimazolambesylate combined with sufentanil anesthesia for elderly patients undergoing percutaneous vertebroplasty (PVP). Forty elderly patients with osteoporotic vertebral compression fractures were assigned to sufentanil alone (A) or remimazolam besylate plus sufentanil (B). HR, MAP, SpO2, and Ramsay sedation scores were recorded at T0–T3, with VAS pain and adverse reactions monitored during recovery. Group B showed higher MAP at T2–T3 and higher sedation at T2, while VAS immediately post-operation and adverse reaction incidence were lower, supporting analgesic and sedative benefits with low respiratory impact and low adverse events.","cbCaisV8O3n3QU5e","https://ap.wps.com/l/cbCaisV8O3n3QU5e","pdf",776453,1,10,"English","en","# Abstract\n# Introduction\n## Background on osteoporosis and OVCF\n## Treatment approach and role of PVP\n## Anesthesia considerations for vertebroplasty\n## Pharmacologic rationale for remimazolam besylate and sufentanil","[{\"question\":\"How were the elderly patients assigned to study groups in this trial?\",\"answer\":\"Forty elderly patients with osteoporotic vertebral compression fractures were randomly divided into group A (sufentanil anesthesia) and group B (remimazolam besylate combined with sufentanil anesthesia).\"},{\"question\":\"Which outcomes were monitored during and after percutaneous vertebroplasty?\",\"answer\":\"Heart rate, mean arterial pressure, pulse oxygen saturation, and Ramsay sedation scores were recorded at multiple time points (T0–T3), while VAS pain scores were measured before anesthesia and immediately after surgery. Adverse reactions such as respiratory depression, nausea/vomiting, and restlessness were observed during recovery.\"},{\"question\":\"What were the key comparative findings between group B and group A?\",\"answer\":\"Compared with group A, group B had higher MAP at T2 and T3 and higher Ramsay sedation scores at T2. Group B also showed a lower VAS score immediately after operation and a lower incidence of adverse reactions.\"}]",1780088581,25,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"study-on-the-combination-of-remimazolam-besylate-and-sufentanil-in-elderly-patients-with-percutaneous-vertebroplasty","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/healthcare/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/study-on-the-combination-of-remimazolam-besylate-and-sufentanil-in-elderly-patients-with-percutaneous-vertebroplasty/31781/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-05-29",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"How were the elderly patients assigned to study groups in this trial?","Question",{"text":73,"@type":74},"Forty elderly patients with osteoporotic vertebral compression fractures were randomly divided into group A (sufentanil anesthesia) and group B (remimazolam besylate combined with sufentanil anesthesia).","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"Which outcomes were monitored during and after percutaneous vertebroplasty?",{"text":78,"@type":74},"Heart rate, mean arterial pressure, pulse oxygen saturation, and Ramsay sedation scores were recorded at multiple time points (T0–T3), while VAS pain scores were measured before anesthesia and immediately after surgery. Adverse reactions such as respiratory depression, nausea/vomiting, and restlessness were observed during recovery.",{"name":80,"@type":71,"acceptedAnswer":81},"What were the key comparative findings between group B and group A?",{"text":82,"@type":74},"Compared with group A, group B had higher MAP at T2 and T3 and higher Ramsay sedation scores at T2. Group B also showed a lower VAS score immediately after operation and a lower incidence of adverse reactions.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]