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Reviews core cardiac arrest fundamentals and an adult algorithm emphasizing reversible causes (H’s and T’s) and high-quality CPR with early defibrillation. Covers major 2015 updates including vasopressin removal, steroid/vasopressin/epinephrine bundle considerations in IHCA, epinephrine use in non-shockable rhythms, alteplase for suspected/confirmed pulmonary embolism, sodium bicarbonate considerations amid shortages, and updates to targeted temperature management during cooling.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/stayin-alive-updates-in-acls-and-post-cardiac-arrest-management/370169/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/stayin-alive-updates-in-acls-and-post-cardiac-arrest-management/370169.png","ImageObject",300,407,{"name":92,"@type":93},"Cart","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What are the objectives of this presentation on ACLS updates?","Question",{"text":113,"@type":114},"The presentation reviews adult cardiac arrest management fundamentals with emphasis on 2015 ACLS guideline changes, evaluates vasopressin removal, discusses alteplase use for suspected/confirmed pulmonary embolism, assesses sodium bicarbonate risk/benefit during shortages, and reviews targeted temperature management changes and cooling-related pharmacologic considerations.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How does the adult cardiac arrest algorithm address reversible causes?",{"text":118,"@type":114},"It focuses on treating reversible causes organized as H’s (including hypovolemia, hypoxemia, acidosis, hypo-/hyperkalemia, and hypothermia) and T’s (including tension pneumothorax, cardiac tamponade, toxins, and thrombosis—pulmonary and coronary).",{"name":120,"@type":111,"acceptedAnswer":121},"What key medication and protocol changes are highlighted in the 2015 ACLS update?",{"text":122,"@type":114},"Vasopressin was removed from the adult cardiac arrest algorithm; early epinephrine is suggested for non-shockable rhythms during cardiac arrest; alteplase is discussed for cardiac arrest due to suspected/confirmed pulmonary embolism; sodium bicarbonate considerations are addressed during a recent drug shortage; and targeted temperature management updates include pharmacologic considerations during cooling.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},370169,1790240487,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146},18829141979164,"https://eur-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Stayin’ Alive:  \nUpdates in ACLS and PostCardiac Arrest Management  \nCorey Witenko, PharmD, BCPS, BCCCP Clinical Pharmacy Manager, Surgical Intensive Care NewYork-Presbyterian Hospital/ Weill Cornell Medical Center  \nOctober 21, 2017  \nDisclosure  \nI have nothing to disclose concerning possible financial or personal relationships with commercial entities (or their competitors) that may be referenced in this presentation.  \nObjectives  \n• Review fundamentals in management of adult cardiac arrest, focusing on changes in the 2015 ACLS guidelines  \n• Discuss evidence utilizing vasopressin during cardiac arrest leading to its removal from theACLS algorithm  \n• Evaluate alteplase administration during cardiac arrest caused by suspected or confirmed pulmonary embolism  \n• Assess benefits and risks associated with sodium bicarbonate use during cardiac arrest given the recent drug shortage  \n• Discuss changes to targeted temperature management postcardiac arrest and pharmacologic considerations during cooling  \nCardiac Arrest  \n• Sudden cessation of cardiac activity where the victim becomes unresponsive, with no normal breathing and no signs of circulation  \n• 2016 statistics  \n• Out-of-hospital cardiac arrest (OHCA)  \n• Incidence: 350,000  \n• Survival to discharge: 12%  \n• In-hospital cardiac arrest (IHCA)  \n• Incidence: 209,000  \n• Survival to discharge: 24.8%  \nLink MS, et al. Circulation. 2015;132:S444-464.  \n[http://www.cpr.heart.org/AHAECC/CPRAndECC/General/UCM_477263_Cardiac-Arrest-Statistics.jsp](http://www.cpr.heart.org/AHAECC/CPRAndECC/General/UCM_477263_Cardiac-Arrest-Statistics.jsp)\\  \nAdult Cardiac Arrest Algorithm  \nLink MS, et al. Circulation. 2015;132:S444-464.  \nAdult Cardiac Arrest Algorithm  \nLink MS, et al. Circulation. 2015;132:S444-464.  \nTreat Reversible Causes  \nH’s  \nHypovolemia  \nHypoxemia  \nHydrogen ion (acidosis)  \nHypo-/  \nhyperkalemia  \nHypothermia  \nT’s  \nTension pneumothorax  \nTamponade (cardiac)  \nToxins  \nThrombosis (pulmonary)  \nThrombosis (coronary)  \nLink MS, et al. Circulation. 2015;132:S444-464.  \nHigh-Quality Evidence?  \n• Few randomized controlled human trials in cardiac arrest  \n• Retrospective  \n• Animal subjects  \n• Case reports/series  \n• Expert consensus  \n•  Cornerstone of therapy: high-quality CPR and early defibrillation  \n•  > 2 inches, 100-120 compressions/min  \n• Allow complete chest recoil  \n• Minimize interruptions  \nLink MS, et al. Circulation. 2015;132:S444-464.  \nMajor Changes in the 2015 Update  \nVasopressin removed from the Adult Cardiac Arrest Algorithm  \nBundle treatment of steroids, vasopressin, and epinephrine may provide some benefit in treating IHCA  \nPrognostication during CPR based on exhaled CO2 measurements  \nIn cardiac arrest with non-shockable rhythm, the early provision of epinephrine is suggested  \nLink MS, et al. Circulation. 2015;132:S444-464.  \nOverview  \nVasopressin removal from ACLS algorithm  \nAlteplase in cardiac arrest due to PE  \nSodium bicarbonate  \nTargeted temperature management","cbCaiv2we9ZKVehk","https://ap.wps.com/l/cbCaiv2we9ZKVehk","pdf",1459621,48,"English","# Objectives\n## Cardiac Arrest Fundamentals and Statistics\n## Adult Cardiac Arrest Algorithm\n### Treat Reversible Causes (H’s and T’s)\n### High-Quality Evidence and Core Therapy\n## Major Changes in the 2015 Update\n### Vasopressin and Bundled Therapies\n### CO2-Based Prognostication\n### Epinephrine in Non-Shockable Rhythms\n## Overview of Key Management Areas","[{\"question\":\"What are the objectives of this presentation on ACLS updates?\",\"answer\":\"The presentation reviews adult cardiac arrest management fundamentals with emphasis on 2015 ACLS guideline changes, evaluates vasopressin removal, discusses alteplase use for suspected/confirmed pulmonary embolism, assesses sodium bicarbonate risk/benefit during shortages, and reviews targeted temperature management changes and cooling-related pharmacologic considerations.\"},{\"question\":\"How does the adult cardiac arrest algorithm address reversible causes?\",\"answer\":\"It focuses on treating reversible causes organized as H’s (including hypovolemia, hypoxemia, acidosis, hypo-/hyperkalemia, and hypothermia) and T’s (including tension pneumothorax, cardiac tamponade, toxins, and thrombosis—pulmonary and coronary).\"},{\"question\":\"What key medication and protocol changes are highlighted in the 2015 ACLS update?\",\"answer\":\"Vasopressin was removed from the adult cardiac arrest algorithm; early epinephrine is suggested for non-shockable rhythms during cardiac arrest; alteplase is discussed for cardiac arrest due to suspected/confirmed pulmonary embolism; sodium bicarbonate considerations are addressed during a recent drug shortage; and targeted temperature management updates include pharmacologic considerations during cooling.\"}]","Stayin’ Alive - Updates in ACLS and Post-Cardiac Arrest Management | PDF",1790187140,121]