[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-326977-105":59,"doc-detail-326977-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","solitary-plasmacytoma-of-the-pancreas-a-rare-case-report","Solitary plasmacytoma of the pancreas - A rare case report","","A plasmacytoma is a malignant proliferation of abnormal plasma cells arising in bone or soft tissue. In soft tissue, it may occur as solitary disease without systemic involvement, sometimes mimicking other pancreatic malignancies when located in the pancreas. This case describes a 62-year-old man diagnosed with solitary pancreatic plasmacytoma. The work emphasizes optimizing diagnosis and management by radiological imaging, particularly computed tomography (CT) and PET-CT, to distinguish it from entities such as pancreatic neuroendocrine tumors.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/solitary-plasmacytoma-of-the-pancreas-a-rare-case-report/326977/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/solitary-plasmacytoma-of-the-pancreas-a-rare-case-report/326977.png","ImageObject",300,407,{"name":92,"@type":93},"Anda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is solitary plasmacytoma of the pancreas and why is it challenging to diagnose?","Question",{"text":113,"@type":114},"It is a rare malignant growth of abnormal plasma cells localized to the pancreas without associated systemic multiple myeloma. It is challenging because pancreatic plasmacytomas can resemble other pancreatic tumors such as pancreatic neuroendocrine tumors, lymphomas, and adenocarcinomas.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How did imaging contribute to reaching the diagnosis in this case?",{"text":118,"@type":114},"CT and pancreatic-protocol CT characterized a heterogeneous mass and vascular/duodenal involvement. PET-CT showed an FDG-avid pancreatic mass consistent with plasmacytoma and suggested possible mesenteric and ascitic involvement.",{"name":120,"@type":111,"acceptedAnswer":121},"What role did pathology and additional tests play after imaging?",{"text":122,"@type":114},"Endoscopic ultrasound-guided fine-needle aspiration showed atypical plasma cells with kappa light-chain restriction, confirming plasmacytoma. Bone marrow biopsy, skeletal survey, and M-spike quantitation were performed to exclude systemic disease.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},326977,1790173265,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":52,"preview_page_count":4},962075006959,"https://ap-avatar.wpscdn.com/avatar/e0002397efbe92a78e?_k=1776741047341049297","Radiology Ca s e Reports 19 (2024) 1806 – 1809  \nAvailable online [at](at www.sciencedirect.com)[ www.sciencedirect.com](at www.sciencedirect.com)  \njournal [homepage:](homepage: www.elsevier.com/locate/radcr)[ www.elsevier.com/locate/radcr](homepage: www.elsevier.com/locate/radcr)  \n| Case Report\u003Cbr>Solitary plasmacytoma of the pancreas: A rare case report ✩\u003Cbr>Ryan C. Rizk, MS, Edmund M. Weisberg, MS, MBE∗, Elliot K. Fishman, MD\u003Cbr>The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 North Caroline St, Baltimore, MD 21287 USA |  |\n| --- | --- |\n| a r t i c l e i n f o | a b s t r a c t\u003Cbr>A plasmacytoma is a cancerous growth of abnormal plasma cells that arise within osseous or soft tissue structures. In soft tissue structures, plasmacytomas can present as solitary or multiple masses in the absence of systemic involvement. Solitary plasmacytomas can be subcategorized as extramedullary plasmacytoma (derived from plasma cells located in soft tissues) or osseous plasmacytoma (derived from plasma cells located in the bone marrow). Infrequently, these tumors can arise as extramedullary lesions from the pancreas and present similarly to other tumors, such as pancreatic neuroendocrine tumors (PNETs) . In this article, we report the case of a 62-year-old male with a diagnosis of solitary plasmacytoma of the pancreas. We focus on optimizing diagnosis and management through the application of radiological imaging modalities, specifically computed tomography (CT) scansand positron emission tomography-computed tomography (PET-CT) scans.\u003Cbr>© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.\u003Cbr>This is an open access article under the CC BY-NC-ND license\u003Cbr>([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/)) |\n| Article history:\u003Cbr>Received 9 September 2023 Revised 2 January 2024 Accepted 23 January 2024 |  |\n| Keywords:\u003Cbr>Pancreatic plasmacytomas Extramedullary plasmacytomas Axial skeleton\u003Cbr>Computed tomography Ultrasound-guided fine-needle aspiration |  |\n\ncreatic tumors seen are primary pancreatic plasmacytomas, without associated multiple myeloma (MM) of the bone marrow [2] . Pancreatic plasmacytomas pose a unique radiological challenge, given their similarity to other pancreatic neoplasms such as pancreatic neuroendocrine tumors (PNETs), lymphomas, and adenocarcinomas [1] . Here, we report a rare case of a 62-year-old male who presented with abdominal pain, nausea, and vomiting that was eventually diagnosed asa solitary plasmacytoma of the pancreas.  \n✩ Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Edmund M. Weisberg, MS, MBE, and Ryan C. Rizk, MS, have no competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Elliot K. Fishman, MD, receives grant funding from GE Healthcare and Siemens, and is a founder and stockholder, HipGraphics.  \n∗ Corresponding author.  \nE-mail address: [eweisbe1@jhmi.edu](eweisbe1@jhmi.edu) (E.M. Weisberg).  \nSocial media:  (R.C. Rizk),  (E.K. Fishman)  \n[https://doi.org/10.1016/j.radcr.2024.01.065](https://doi.org/10.1016/j.radcr.2024.01.065)  \n1930-0433/© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/))  \nCase presentation  \nA 62-year-old African American male with a past medical history of hypertension presented to the emergency department with nausea, vomiting, and abdominal pain. Upon physical examination, the patient’s abdomen was soft and distended with epigastric tenderness to palpation. Initial complete blood count, urinalysis, and lipase levels were unremarkable. Subseq","cbCaiqb1NWsSv2wR","https://ap.wps.com/l/cbCaiqb1NWsSv2wR","pdf",928995,"English","# Case Report\n## Case presentation","[{\"question\":\"What is solitary plasmacytoma of the pancreas and why is it challenging to diagnose?\",\"answer\":\"It is a rare malignant growth of abnormal plasma cells localized to the pancreas without associated systemic multiple myeloma. It is challenging because pancreatic plasmacytomas can resemble other pancreatic tumors such as pancreatic neuroendocrine tumors, lymphomas, and adenocarcinomas.\"},{\"question\":\"How did imaging contribute to reaching the diagnosis in this case?\",\"answer\":\"CT and pancreatic-protocol CT characterized a heterogeneous mass and vascular/duodenal involvement. PET-CT showed an FDG-avid pancreatic mass consistent with plasmacytoma and suggested possible mesenteric and ascitic involvement.\"},{\"question\":\"What role did pathology and additional tests play after imaging?\",\"answer\":\"Endoscopic ultrasound-guided fine-needle aspiration showed atypical plasma cells with kappa light-chain restriction, confirming plasmacytoma. Bone marrow biopsy, skeletal survey, and M-spike quantitation were performed to exclude systemic disease.\"}]","Solitary plasmacytoma of the pancreas - A rare case report | PDF",1789975898]