[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-424029-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-424029-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","social-support-metabolic-syndrome-and-white-matter-hyperintensities-in-mexican-americans","SOCIAL SUPPORT, METABOLIC SYNDROME, AND WHITE MATTER HYPERINTENSITIES IN MEXICAN AMERICANS","","Mexican Americans experience disproportionate cardiovascular burden, increasing vulnerability to brain impairment via white matter hyperintensities (WMH) and elevating dementia risk. Metabolic syndrome (MetS) is an early indicator of cardiovascular disease, and social support may represent a protective sociocultural factor. This study assessed the association between MetS and WMH and tested whether social support moderated that relationship in 1,050 Mexican American adults aged 50–91 using MRI and validated scales.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/social-support-metabolic-syndrome-and-white-matter-hyperintensities-in-mexican-americans/424029/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/social-support-metabolic-syndrome-and-white-matter-hyperintensities-in-mexican-americans/424029.png","ImageObject",300,407,{"name":42,"@type":43},"Rizky","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",10,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"How were metabolic syndrome and WMH assessed in the study?","Question",{"text":63,"@type":64},"MetS was diagnosed using Adult Treatment Panel III criteria, classifying participants as MetS+ or MetS-. WMH volumes were measured with a 3T MRI system, with higher values indicating more damage.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What statistical approaches were used to test the hypotheses?",{"text":68,"@type":64},"Linear regression examined independent effects of MetS and WMH volume, and an ANCOVA model assessed interactive effects involving social support. Models adjusted for age, sex, and education.",{"name":70,"@type":61,"acceptedAnswer":71},"Did social support change the relationship between metabolic syndrome and WMH?",{"text":72,"@type":64},"No. Although MetS+ was significantly associated with higher WMH volumes, the association did not vary significantly across levels of social support.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},424029,1791102748,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":116,"doc_module":4,"doc_module_name":25,"category_name":117,"show_sort_weight":118,"slug":119},9,"Religion & Spirituality",20,"religion-spirituality",{"id":118,"doc_module":4,"doc_module_name":25,"category_name":121,"show_sort_weight":118,"slug":122},"World Cup","world-cup",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":55,"slug":125},"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":26,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":97,"preview_page_count":4},962085564807,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","724 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.2466  \nSOCIAL SUPPORT, METABOLIC SYNDROME, AND WHITE MATTER HYPERINTENSITIES IN MEXICAN AMERICANS  \nZoraida Garcia1, Jordana Breton2, Lourdes RomañachÁlvarez2, and Elizabeth Muñoz1, 1. University of Texas at Austin, Austin, Texas, United States, 2. The University of Texas  \nat Austin, Austin, Texas, United States  \nInnovation in Aging, 2025, Vol. 9, No. S2 725  \nMexican Americans (MA) are disproportionally affected by poor cardiovascular health, making them susceptible to brain impairment through White Matter Hyperintensities (WMH), increasing dementia risk. Metabolic Syndrome (MetS) is an early marker of cardiovascular disease, and one potential sociocultural factor that may be protective against conditions of MetS among MA is social support. We examined the link between MetS and WMH and whether social support moderated this association.  \nOur sample consisted of 1,050 MA adults (ages 50-91) from the Health and Aging Brain Study: Health Disparities (HABS-HD) .  \nMetS was diagnosed using the Adult Treatment Panel III criteria (MetS+/MetS-), WMH volumes were measured through a 3T MRI System with higher values indicating more damage, and social support was calculated with the 12-item Interpersonal Support Evaluation List. We used linear regression to examine the independent effects of MetS and WMH volume, and an ANCOVA model to assess the interactive effects of social support on MetS and WMH volume. Models adjusted for age, sex, and education. Independent effects revealed that MetS+ status was significantly associated with higher WMH volumes (B = 0.32, p\u003C 0.05, R2=0.25). This association did not vary by levels of social support WMH (F[5,1041]=2.91, p=0.08, ηp2\u003C.001) . Results suggest that MetS+ exacerbates WMH, and that social support does not impact the link between MetS and WMH. Future studies should investigate other potential sociocultural resiliency factors that may buffer the impact of MetS on WMH in middle-aged and older MA adults.","cbCaijdf6I4kvrnT","https://ap.wps.com/l/cbCaijdf6I4kvrnT","pdf",1282342,"English","# Methods\n## Sample and measures\n## Statistical models\n# Results\n## MetS and WMH association\n## Moderation by social support\n# Implications\n## Future research directions","[{\"question\":\"How were metabolic syndrome and WMH assessed in the study?\",\"answer\":\"MetS was diagnosed using Adult Treatment Panel III criteria, classifying participants as MetS+ or MetS-. WMH volumes were measured with a 3T MRI system, with higher values indicating more damage.\"},{\"question\":\"What statistical approaches were used to test the hypotheses?\",\"answer\":\"Linear regression examined independent effects of MetS and WMH volume, and an ANCOVA model assessed interactive effects involving social support. Models adjusted for age, sex, and education.\"},{\"question\":\"Did social support change the relationship between metabolic syndrome and WMH?\",\"answer\":\"No. Although MetS+ was significantly associated with higher WMH volumes, the association did not vary significantly across levels of social support.\"}]","SOCIAL SUPPORT, METABOLIC SYNDROME, AND WHITE MATTER HYPERINTENSITIES IN MEXICAN AMERICANS | PDF",1790632705]